CardioTabs for a Healthy Heart

CardioTabs for a Healthy Heart

• 1.
  CardioTabs nutritional supplementsare developed by leaders in the field of preventive cardiology to provide their patients and yours with the right nutritional support for a healthy heart. CardioDaily (multivitamin and mineral supplement, now with 2,000 IU Vitamin D3)
• 2.
  Omega-3 Fish Oil(highly concentrated DHA/EPA supplement in a small (550 mg) softgel with burp and aftertaste-free enteric coating and lemon scent)
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  Omega-3 Fish OilPURITYMolecularDistillation (purification process)
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  Independently tested byFDA-registered laboratory
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  Free of anydetectable amounts of heavy metals like mercury, cadmium, and lead and pollutants such as dioxins and PCB’s.
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  DHA:EPA ratio similarto that found naturally in fatty fish (see following slide)
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  Small Pill –CardioTabs Omega-3 softgels are about half the size of common chain store brands
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  Enteric Coating –No fishy burp or aftertaste. Lemon scent eliminates fishy odor.DHA Content of Fish and Fish Oils
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  AJCN – Supplementingwith CardioTabs Omega-3 Fish Oil has Same Effect on Red Blood Cell Levels of DHA and EPA as Eating Fatty Fish (salmon and tuna)Both fish [salmon and tuna]and fish oil capsules [CardioTabs Omega-3 Fish Oil] had the same effect on the major long chain omega-6 and omega-3 fatty acids measured in the red blood cells or in plasma phospholipids.Researchers said they used CardioTabs Omega-3 Fish Oil because “its fatty acid composition is more reflective of that of salmon and tuna (i.e., it is DHA rich) than is that of most supplements, which typically are EPA rich.”Harris WS, Pottala JV, Sands SA, Jones PG. Comparison of the effects of fish and fish-oil capsules on the n-3 fatty acid content of blood cells and plasma phospholipids. Am J Clin Nutr 2007; 86: 1621-5.
• 10.
  Omega-3 ReferencesAHA 2002.American Heart Association Scientific Statement: Fish consumption, fish oil, omega-3 fatty acids, and cardiovascular disease. Circulation 2002; 106:2747-2757. 
• 11.
  Albert CM, CamposH, Stampfer MJ, et al. Blood levels of long-chain n-3 fatty acids and the risk of sudden death. NEJM 2002; 346:1113-1118.
• 12.
  AHRQ 2004. Agencyfor Healthcare Research and Quality, Evidence Report Number 94. Effects of omega-3 fatty acids on cardiovascular disease. March 2004. Available from ARHQ website. Belluzzi A, Brignola C, Campieri M, et al. Effect of an enteric-coated fish-oil preparation on relapses in crohns’ disease. NEJM 1996; 334:1557-60.
• 13.
  Bucher HC, HengstlerP, Schindler C, et al. N-3 polyunsaturated fatty acids in coronary heart disease: a meta-analysis of randomized controlled trials. Am J Med. 2002; 112:298–304. Burr ML, Fehily AM, Gilbert JF, et al. Effects of changes in fat, fish, and fibre intakes on death and myocardial reinfarction: diet and reinfarction trial (DART). Lancet 1989; 2:757–761.
• 14.
  Connor WE. Importanceof n-3 fatty acids in health and disease. Am J Clin Nutr 2000; 71(1 Suppl):171S–175S.
• 15.
  Department of Healthand Human Services, US Food and Drug Administration. Substances affirmed as generally recognized as safe: menhaden oil. FederalRegister. June 5, 1997. Vol. 62, No. 108: pp 30751–30757. 21 CFR Part 184 [Docket No. 86G-0289]. Available at: http://frwebgate5.access.gpo.gov/cgi-bin/PDFgate.cgi?WAISdocID=307943177881+1+2+0&WAISaction=retrieve. Accessed March 17, 2009.
• 16.
  Erkkila AT, LichtensteinAH, Mozaffarian D, et al. Fish intake is associated with a reduced progression of coronary artery atherosclerosis in postmenopausal women with coronary artery disease. Am J Clin Nutr 2004; 80(3):626-632.
• 17.
  GISSI Prevenzione Investigators.Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E after myocardial infarction: results of the GISSI-Prevenzione trial. GruppoItaliano per lo Studio dellaSopravvivenzanell'Infartomiocardico. Lancet 1999 Aug 7; 354(9177):447-55.
• 18.
  Harris WS, Pottala JV, Sands SA, Jones PG. Comparison of the effects of fish and fish-oil capsules on the n-3 fatty acid content of blood cells and plasma phospholipids. Am J Clin Nutr 2007; 86: 1621-5. Omega-3 References Cont. Hu FB, Bronner L, Willett WC, et al. Fish and omega-3 fatty acid intake and risk of coronary heart disease in women. JAMA. 2002; 287:1815–1821.  Innis SM. Dietary (n-3) fatty acids and brain development. J Nutr 2007; 137:855-859.
• 19.
  Krauss RM, EckelRH, Howard B, et al. AHA Dietary Guidelines: revision 2000: a statement for healthcare professionals from the Nutrition Committee of the American Heart Association. Circulation 2000; 102:2284–2299.
• 20.
  Lee JH, O’KeefeJH, Lavie CJ, et al. Omega-3 fatty acids for cardioprotection. Mayo Clin Proc 2008; 83(3):324-332.
• 21.
  Marchioli R, BarziF, Bomba E, et al. Early protection against sudden death by n-3 polyunsaturated fatty acids after myocardial infarction: time-course analysis of the results of the GruppoItaliano per lo Studio dellaSopravvivenzanell’InfartoMiocardico (GISSI)-Prevenzione. Circulation 2002; 105:1897–1903.
• 22.
  O’Keefe JH, HarrisWS. From Inuit to implementation: Omega-3 fatty acids come of age. Mayo Clin Proc 2000; 75:607-614.
• 23.
  Richardson, A.J., Montgomery,P. The Oxford-Durham study: a randomized, controlled trial of dietary supplementation with fatty acids in children with developmental coordination disorder. Pediatrics 2005 May; 115(5):1360-6.
• 24.
  Stone NJ. Fishconsumption, fish oil, lipids, and coronary heart disease. Circulation 1996; 94:2337–2340.
• 25.
  Yokoyama M, OrigasaH, Matsuzaki M, et al. Effects of eicosapentaenoic acid on major coronary events in hypercholesterolaemic patients (JELIS): a randomised open-label, blinded endpoint analysis. The Lancet 2007; 369:1090-1098. CardioDaily
• 26.
  CardioDailyNow with 2,000IU Vitamin D3
• 27.
  “Vitamin D deficiencyis a common, potent and easily treated CV risk factor” – James O’Keefe, MD
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  Safe, effective andaffordable combination
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  No Vitamin K(safe for patients on blood thinning meds), Iron, or Calcium
• 30.
  One, easy toswallow capsule – can be opened and sprinkled on food or in liquid for those who cannot swallow pillsCardioDaily ReferencesFletcher RH, Fairfield KM, Vitamins for chronic disease prevention in adults. JAMA. 2002 June 19;287 (23):3127-9.
• 31.
  Forman J, RimmE, Stmpfer M, Curhan G, Folate intake and the risk of incident hypertension among US women. JAMA. 2005;293:320-329.
• 32.
  Holick M, Sunlightand vitamin D for bone health and prevention of autoimmune disease, cancers, and cardiovascular disease. Am J Clin Nutr 2004;80:1678S-88S.
• 33.
  Lee J, O'KeefeJ, Bell D, Donald D, Hensrud, Holick M, Vitamin D Deficiency: An Important, Common, and Easily Treatable Cardiovascular Risk Factor? J Am Coll Cardiol 2008;52:1949-1956.
• 34.
  Robinson K, ArheartK,Refsum H, et al. Low circulating folate and vitamin B6 concentrations: Risk factors for stroke, peripheral vascular disease, and coronary artery disease: European COMAC Group. Circulation. 1998;97:437-443.
• 35.
  Title LM, CummingsPM, Diddens K, Genest JJ, Nassar B. Effects of folic acid and antioxidant vitamins on endothelial dysfunction in patients with coronary artery disease. JACC. 2000 Sep; 36(3):758-65.
• 36.
  Varosy PD, BrownerWS, Ensrud KE, Stone KL, Reid IR, Hillier T, Cummings ST. Vitamin D supplements use and the risk of coronary heart disease mortality in older women. Abstract presented at the 42nd Annual Conference on Cardiovascular Disease Epidemiology and Prevention. 2002 Apr.
• 37.
  Vieth R, etal. The urgent need to recommend an intake of vitamin D that is effective. Am J Clin Nutr 85:649-650;2007