Central venous access devices (CVADs) are catheters inserted into thoracic central veins for various medical purposes, including inadequate peripheral access and hemodynamic monitoring. Different types of CVADs exist, such as nontunneled, tunneled, and peripherally inserted central catheters (PICCs), each with specific advantages and risks. Proper preprocedural preparation, insertion techniques, and guidelines for removal are essential for minimizing complications and ensuring patient safety.