Chapter 10 of 'Hands-On Ethical Hacking and Network Defense' focuses on web application vulnerabilities, describing key components like static and dynamic web pages, and tools used to attack web servers. It highlights common vulnerabilities such as cross-site scripting (XSS), SQL injection, and the importance of securing web applications against attacks that can compromise user data or server integrity. Additionally, it discusses various technologies and languages used in web development, including CGI, ASP, PHP, and JavaScript.