The Motivated and
Emotional Br ain

 Chapter 3
THE MOTIVATED AND EMOTIONAL BRAIN


 Why is the Brain Important?
                           Thinking Brain
    Brain            Cognitive and Intellectual Functions
                            “What task it is doing”




                          Motivated Brain
                         “Whether you want to do it”




                          Emotional Brain
                     “What your mood is while doing it”
The Motivated And Emotional
Br ain
          Three Principles
The Motivated Brain
Food Deprivation Activates the Ghrelin Release that Stimulates
the Hypothalamus to Create Hunger




Figure 3.2
The Emotional Brain
Good Event Activates The Dopamine Release That
Stimulates Positive Affect
Look Inside The Brain
Two Ways of Looking inside the Brain
• Surgeon’s View
• Functional Magnetic Resonance Imaging (fMRI)




                                       Figure 3.5
                                       Cross Section of the Brain Showing
                                       the Anatomic Position of the Key
                                       Brain Structures Involved in
                                       Motivation and Emotion
Motivational and Emotional States
         Associated with
Approach-Oriented Brain Structure
Br ain                        Associated Motivational or Emotional
Structure                                  Experience

Hypothalamus             Pleasurable feelings associated with feeding, drinking, mating
Medial forebr ain
bundle                   Pleasure, reinforcement

Orbitofrontal cor te x   Learning the incentive value of events, making choices
Sep tal area             Pleasure center associated with sociability, sexuality
Nucleus accumbens        Pleasurable experience of reward, hotspot for liking
Anterior cingulate
corte x                  Mood, volition, making choices

Cerebr al corte x
(Frontal lobes)          Making plans, setting goals, formulating intentions

Lef t prefrontal
cerebr al corte x        Approach motivational and emotional tendencies

Medial prefrontal        Learning response-outcome contingencies that underlie
cerebr al corte x        perceived control beliefs and mastery motivation
Hypothalamus
 Comprises less than 1% of the total volume of the brain
 “motivational giant”
 Stimulation generates wants for, and the pleasures associated
  with, water, food, and sexual partners
 Regulates the endocrine and automatic nervous system
 Therefore it is able to regulate the body’s internal environment
  so to adapt optimally to the external environment
   Ex. Internal (heart rate, hormone secretion) to cope with an External
    stressor
Medial Forebrain Bundle
 “Pleasure Center”
 Stimulation creates pleasure and leads
  animals to act as if they have just received (+)
  reinforcement
 In humans, stimulation produces general
  positive feelings
Orbitofrontal Cortex
 Processes incentive-related information
 Helps people make choices between options
 For example- which product to buy or what to
  drink
Septo-Hippocampal Circuit
 Forecasts the emotion associated with
  upcoming events in terms of both anticipated
  pleasure and anticipated anxiety
 Nucleus Accumbens- plays a critical role in
  the experience of pleasure form naturally
  occurring reinforces (good food, social
  acceptance)
 Includes Hippocampus (Avoidance-oriented)
Anterior Cingulate Cortex
 Involved in the control of day-to-day mood,
  volition, and choices
 Decreased activity is associated with sadness
  and depression
 Important to the mental activity underlying
  the act of “making a choice”
Medial Prefrontal Cortex
 Central role in the learning of response-
  outcome contingencies
 “When I study, I make good grades”
 Important to goal-directed, outcome seeking
  action
Left Prefrontal Cortex
 Prefrontal Cortex houses a person’s concious
  goals
 Goals routinely compete against one another
  (goal to eat vs. goal to lose weight)
 Positive approach oriented feelings
 Personality differences (more sensitive left vs.
  right prefrontal lobe)
Motivational and Emotional States
            Associated with
   Avoidance-Oriented Brain Structure




Brain Structure            Associated Motivational or Emotional
                           Experience



Right
prefrontal        Withdraw motivational and emotional tendencies
cerebr al cor tex
                           Detecting and responding to threat and danger
Amygdala
                           (e.g., via fear, anger, and anxiety)
Hippocampus                Behavior inhibition system during unexpected events
      Table 3.1 Motivational and Emotional States Associated with Specific Brain Structure
Right Prefrontal Cortex
 Negative and avoidance oriented feelings
 Negative emotionality
 Related to a personality oriented toward
  anxiety and avoidance orientations
Amygdala
 Detects and responds to threatening and
  emotionally significant events
 Regulates the emotions involved in self-
  preservation (fear, anger, anxiety)
 Each nuclei serves a different function
   Emotional anger

   Fear and defensive behavior
Hippocampus
 Operates as a “comparator” that instantly
  compares incoming sensory information with
  expected events (from memory)
 If events do not unfold as expected the
  hippocampus acts in “not okay” mode
   Activates septo-hippocampal circuit

   Generates an anxiety-ridden motivational state
    that takes control over behavior
Arousal
   Motivational and Emotional States Associated with
           Arousal-Oriented Brain Structure


Brain Structure       Associated Motivational or Emotional Experience
                           Alert/aroused cortex processes
                           information, makes a decision, and

Reticular formation   Arousal
                           responds appropriately




                                                     Figure 3.6
                                Anatomy (a) and Function (b) of the Reticular Formation
NEUROTRANSMITTER PATHWAYS IN
THE BRAIN

 Neurotransmitter Pathway
  : A cluster of neurons that communicate with other neurons
    by using one particular neurotransmitter

 Four Motivationally Relevant Neurotransmitter Pathways

  1. Dopamine
  2. Serotonin
  3. Norepinephrine
  4. Endorphin
Dopamine
Dopamine
Hormones In The Body


Essential Hormones underlying Motivation, Emotion, and Behavior
The World In Which Brain Lives

Ch03(1)

  • 1.
  • 2.
    THE MOTIVATED ANDEMOTIONAL BRAIN Why is the Brain Important? Thinking Brain Brain Cognitive and Intellectual Functions “What task it is doing” Motivated Brain “Whether you want to do it” Emotional Brain “What your mood is while doing it”
  • 3.
    The Motivated AndEmotional Br ain Three Principles
  • 4.
    The Motivated Brain FoodDeprivation Activates the Ghrelin Release that Stimulates the Hypothalamus to Create Hunger Figure 3.2
  • 5.
    The Emotional Brain GoodEvent Activates The Dopamine Release That Stimulates Positive Affect
  • 6.
    Look Inside TheBrain Two Ways of Looking inside the Brain • Surgeon’s View • Functional Magnetic Resonance Imaging (fMRI) Figure 3.5 Cross Section of the Brain Showing the Anatomic Position of the Key Brain Structures Involved in Motivation and Emotion
  • 7.
    Motivational and EmotionalStates Associated with Approach-Oriented Brain Structure Br ain Associated Motivational or Emotional Structure Experience Hypothalamus Pleasurable feelings associated with feeding, drinking, mating Medial forebr ain bundle Pleasure, reinforcement Orbitofrontal cor te x Learning the incentive value of events, making choices Sep tal area Pleasure center associated with sociability, sexuality Nucleus accumbens Pleasurable experience of reward, hotspot for liking Anterior cingulate corte x Mood, volition, making choices Cerebr al corte x (Frontal lobes) Making plans, setting goals, formulating intentions Lef t prefrontal cerebr al corte x Approach motivational and emotional tendencies Medial prefrontal Learning response-outcome contingencies that underlie cerebr al corte x perceived control beliefs and mastery motivation
  • 8.
    Hypothalamus  Comprises lessthan 1% of the total volume of the brain  “motivational giant”  Stimulation generates wants for, and the pleasures associated with, water, food, and sexual partners  Regulates the endocrine and automatic nervous system  Therefore it is able to regulate the body’s internal environment so to adapt optimally to the external environment  Ex. Internal (heart rate, hormone secretion) to cope with an External stressor
  • 9.
    Medial Forebrain Bundle “Pleasure Center”  Stimulation creates pleasure and leads animals to act as if they have just received (+) reinforcement  In humans, stimulation produces general positive feelings
  • 10.
    Orbitofrontal Cortex  Processesincentive-related information  Helps people make choices between options  For example- which product to buy or what to drink
  • 11.
    Septo-Hippocampal Circuit  Forecaststhe emotion associated with upcoming events in terms of both anticipated pleasure and anticipated anxiety  Nucleus Accumbens- plays a critical role in the experience of pleasure form naturally occurring reinforces (good food, social acceptance)  Includes Hippocampus (Avoidance-oriented)
  • 12.
    Anterior Cingulate Cortex Involved in the control of day-to-day mood, volition, and choices  Decreased activity is associated with sadness and depression  Important to the mental activity underlying the act of “making a choice”
  • 13.
    Medial Prefrontal Cortex Central role in the learning of response- outcome contingencies  “When I study, I make good grades”  Important to goal-directed, outcome seeking action
  • 14.
    Left Prefrontal Cortex Prefrontal Cortex houses a person’s concious goals  Goals routinely compete against one another (goal to eat vs. goal to lose weight)  Positive approach oriented feelings  Personality differences (more sensitive left vs. right prefrontal lobe)
  • 15.
    Motivational and EmotionalStates Associated with Avoidance-Oriented Brain Structure Brain Structure Associated Motivational or Emotional Experience Right prefrontal Withdraw motivational and emotional tendencies cerebr al cor tex Detecting and responding to threat and danger Amygdala (e.g., via fear, anger, and anxiety) Hippocampus Behavior inhibition system during unexpected events Table 3.1 Motivational and Emotional States Associated with Specific Brain Structure
  • 16.
    Right Prefrontal Cortex Negative and avoidance oriented feelings  Negative emotionality  Related to a personality oriented toward anxiety and avoidance orientations
  • 17.
    Amygdala  Detects andresponds to threatening and emotionally significant events  Regulates the emotions involved in self- preservation (fear, anger, anxiety)  Each nuclei serves a different function  Emotional anger  Fear and defensive behavior
  • 18.
    Hippocampus  Operates asa “comparator” that instantly compares incoming sensory information with expected events (from memory)  If events do not unfold as expected the hippocampus acts in “not okay” mode  Activates septo-hippocampal circuit  Generates an anxiety-ridden motivational state that takes control over behavior
  • 19.
    Arousal Motivational and Emotional States Associated with Arousal-Oriented Brain Structure Brain Structure Associated Motivational or Emotional Experience Alert/aroused cortex processes information, makes a decision, and Reticular formation Arousal responds appropriately Figure 3.6 Anatomy (a) and Function (b) of the Reticular Formation
  • 20.
    NEUROTRANSMITTER PATHWAYS IN THEBRAIN  Neurotransmitter Pathway : A cluster of neurons that communicate with other neurons by using one particular neurotransmitter  Four Motivationally Relevant Neurotransmitter Pathways 1. Dopamine 2. Serotonin 3. Norepinephrine 4. Endorphin
  • 21.
  • 22.
  • 23.
    Hormones In TheBody Essential Hormones underlying Motivation, Emotion, and Behavior
  • 24.
    The World InWhich Brain Lives