1) Packet-switched networks necessarily constrain throughput, introduce delays, and can lose packets due to processing, queuing, transmission, and propagation delays at each node along the transmission path.
2) The total nodal delay at each node equals the processing delay plus the queuing delay plus the transmission delay plus the propagation delay.
3) End-to-end delay is calculated by summing the total nodal delays across all nodes between the source and destination.