This document outlines objectives for reviewing the molecular basis of inheritance. It covers: (1) the experiments that provided evidence DNA is the genetic material, including those by Griffith, Avery, McCarty, MacLeod, Hershey and Chase, and Chargaff; (2) how Watson and Crick deduced the double helix structure of DNA and its significance; (3) DNA replication including the semiconservative model and roles of DNA polymerase and other proteins.