Checking in on healthcare data
analytics
Christopher Naugler
Associate Professor
Pathology and Laboratory Medicine
University of Calgary
Healthcare data
• Transformative changes:
– Accrual of large historic datasets
– Interoperability of systems
– Data warehouses
• Opportunities
– Provide epidemiological data
– Assess value in health spending
– Provide new insights for increasing value
Challenges
• Traditional analytic techniques not scalable to
big data
• Trans border data flows into the United States
and the USA PATRIOT Act
• Need bricks and mortar big data solutions
• Lack of infrastructure
• Lack of expertise
What is big data in pathology?
• Genome sequences: bioinformatics
– Shah NH. Translational bioinformatics embraces big data.
Yearbook of Medical Informatics 2011:7:130-134.
• Imaging analysis and storage
– Mohammed EA, Far BH, Naugler C. Peripheral Blood Smear
Image Analysis: A comprehensive review. Journal of Pathology
Informatics 2014;5:9
• Massive lab/clinical datasets
– Mohammed EA, Far BH, Naugler C. Applications of the
MapReduce Programming Framework to Clinical Big Data
Analysis: Current Landscape and Future Trends. BioData
Mining, in press
Example – Calgary Laboratory data
• Since 2010: 125,000,000 lab tests
• Each with 100+ pieces of metadata
– 1.25 x 1010
data elements
• Linkage to demographic, pharmacy,outcomes
data
– 1.25 x 1012
data elements
15-10-05 6
Calgary TSH Test
Edmonton TSH Test
Total expenditures by specialty
•Naugler C, Thomas R, Turin TC, Guo M, Vaska M. Am J Clin Pathol in press
Laboratory testing costs by physician
Numberofprimarycarephysicians
Yearly cost of laboratory tests ($CDN)
Redundant laboratory tests
• Morgen E, Naugler C. Am J Clin Pathol in press
Abnormal Rate per Number of
Tests
ROCs for FIT screening
PSA testing in the
city of Calgary
Gorday, W, Sadzradeh H, de
Koning L, Naugler C.
Sociodemographic variables
associated with PSA testing.
Clin Biochem 2014;47:164-169.
Colon Cancer
Screening
• There is marked
variation in
screening rates
throughout Calgary,
related to a number
of sociodemographic
factors
• Crouse AL, Sadrzadeh H, de
Koning L, Naugler C. Clin
Biochem 2015;48:105-109.
Contact
• Christopher.naugler@cls.ab.ca

Checking in on Healthcare Data Analytics

  • 1.
    Checking in onhealthcare data analytics Christopher Naugler Associate Professor Pathology and Laboratory Medicine University of Calgary
  • 2.
    Healthcare data • Transformativechanges: – Accrual of large historic datasets – Interoperability of systems – Data warehouses • Opportunities – Provide epidemiological data – Assess value in health spending – Provide new insights for increasing value
  • 3.
    Challenges • Traditional analytictechniques not scalable to big data • Trans border data flows into the United States and the USA PATRIOT Act • Need bricks and mortar big data solutions • Lack of infrastructure • Lack of expertise
  • 4.
    What is bigdata in pathology? • Genome sequences: bioinformatics – Shah NH. Translational bioinformatics embraces big data. Yearbook of Medical Informatics 2011:7:130-134. • Imaging analysis and storage – Mohammed EA, Far BH, Naugler C. Peripheral Blood Smear Image Analysis: A comprehensive review. Journal of Pathology Informatics 2014;5:9 • Massive lab/clinical datasets – Mohammed EA, Far BH, Naugler C. Applications of the MapReduce Programming Framework to Clinical Big Data Analysis: Current Landscape and Future Trends. BioData Mining, in press
  • 5.
    Example – CalgaryLaboratory data • Since 2010: 125,000,000 lab tests • Each with 100+ pieces of metadata – 1.25 x 1010 data elements • Linkage to demographic, pharmacy,outcomes data – 1.25 x 1012 data elements
  • 6.
  • 7.
  • 8.
  • 9.
    Total expenditures byspecialty •Naugler C, Thomas R, Turin TC, Guo M, Vaska M. Am J Clin Pathol in press
  • 10.
    Laboratory testing costsby physician Numberofprimarycarephysicians Yearly cost of laboratory tests ($CDN)
  • 11.
    Redundant laboratory tests •Morgen E, Naugler C. Am J Clin Pathol in press
  • 12.
    Abnormal Rate perNumber of Tests
  • 14.
    ROCs for FITscreening
  • 15.
    PSA testing inthe city of Calgary Gorday, W, Sadzradeh H, de Koning L, Naugler C. Sociodemographic variables associated with PSA testing. Clin Biochem 2014;47:164-169.
  • 16.
    Colon Cancer Screening • Thereis marked variation in screening rates throughout Calgary, related to a number of sociodemographic factors • Crouse AL, Sadrzadeh H, de Koning L, Naugler C. Clin Biochem 2015;48:105-109.
  • 17.