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IJRET: International Journal of Research in Engineering and Technology eISSN: 2319-1163 | pISSN: 2321-7308
__________________________________________________________________________________________
Volume: 03 Issue: 03 | Mar-2014, Available @ http://www.ijret.org 145
CLUSTERING OF MEDLINE DOCUMENTS USING SEMI-SUPERVISED
SPECTRAL CLUSTERING
AbinCherian1
, D.Saravanan2
, A.Jesudoss3
1
Department of Computer Application, 2, 3
Asst. Professor, MCA, Sathyabama University, Chennai-600119
Abstract
We are considering: local-content (LC) information, global-content (GC) information from PubMed and MESH (medical subject
heading-MS) for the clustering of bio-medical documents. The performances of MEDLINE document clustering are enhanced from
previous methods by combining both the LC and GC. We propose a semi-supervised spectral clustering method to overcome the
limitations of representation space of earlier methods.
Keywords- document clustering, semi-supervised clustering, spectral clustering
-------------------------------------------------------------------------***---------------------------------------------------------------------
1. INTRODUCTION
The major searching target over biomedical documents is
MEDLINE, which is covering around 5600 life science
journals published worldwide. We know that document
clustering is grouping similar documents together and
separating dissimilar documents automatically, contributes
greatly to manage and organize literatures, navigate and locate
searching results, and provide personalized information
services. Only local-content (LC) information of documents
from the data set to be clustered has been utilized for
clustering.
PubMed provides a set of related articles in the whole
MEDLINE collection which usually compares words from the
title, the abstract, and the medical subject heading for each
MEDLINE document.
2. EXISTING SYSTEM
There are two categories named constraint-based and distance
based in the existing method. Constraint-based methods have
user-provided labels or constraints to guide the algorithm
towards a more appropriate data partitioning. By modifying
the objective function for evaluating clustering’s, it is done.
Thus it includes satisfying constraints, enforcing constraints
during the clustering process, or initializing and constraining
the clustering based on labeled examples. An existing
clustering algorithm that uses a particular clustering distortion
measure is employed in the distance-based category. It is
trained to satisfy the labels or constraints in the supervised
data here.
2.1 Existing System Technique
K-mean’s clustering
1. Choose the number of different clusters, k.
2. Generate k clusters randomly and determine where the
cluster centers.
3. Assign each point to the nearest cluster center, where we
can define "nearest" wrt one of the distance measures
discussed.
4. Recompute the new cluster centers.
5. Repeat the previous steps until some convergence criterion
is met.
2.2 Existing System Drawbacks
1. True similarity would not be a simple linear relationship
between different similarities.
2. The quality of similarity in a data set may not be same for
all document pairs. Some pairs may be more reliable and need
more attention.
3. Existing system couldn’t manage with a suitable weighting
configuration to balance three or more different types of
similarities in integrating them.
3. PROPOSED SYSTEM-
To improve the clustering performance, Semi supervised
spectral clustering algorithms are used. The prior knowledge
to improve clustering is usually provided by labeled instances
or, more typically, by two types of constraints, i.e., must-link
(ML) and cannot-link (CL), where ML means that the two
corresponding examples should be in the same cluster and CL
means that the two corresponding examples which we are
considering should not be in the same cluster. We know that
the Spectral clustering is a well accepted method for clustering
nodes over a graph or an adjacency matrix, where clustering is
IJRET: International Journal of Research in Engineering and Technology eISSN: 2319-1163 | pISSN: 2321-7308
__________________________________________________________________________________________
Volume: 03 Issue: 03 | Mar-2014, Available @ http://www.ijret.org 146
a graph cut problem that can be solved by matrix trace
optimization.
3.1 Overall Diagram
3.2 Scope of the Project
By improving the performance, we have gone for alternative
methods where user can search Biomedical text in our project.
Usually, when user will search any text, it has to follow online
databases. For searching about biomedical text, user can
search documents from PubMed, Medline, PMC, Mesh, etc.
These databases contain bulk amount of data. The retrieving
of documents from these databases makes the performance
slow. For this, we can provide option where to get documents,
either from online databases or from our local database. We
will make clustering of all our local database documents and
can get documents from different clusters with the rank.
3.3 Proposed System Technique
Semi-supervised spectral clustering
We usually use Medline, PubMed or some other databases for
searching biomedical related documents. In all these databases
huge number of documents are available. While retrieving
those documents, performance will get slow .Hence we can
retrieve some selected documents in our local database. Thus
the performance could be increased. And if we go for second
time search, No need to go for online Database. Get it from
our local database only.
In our proposed algorithm, set of documents V (= {v1, v2, . . .
,vN}) has to be clustered. Let Sim(·, ·) be the function
showing similarity between two inputs, and for example,
Sim(M,M_) outputs similarity between two MeSH main
headings M and M_.We denote the LC similarity matrix
byWlwith the (i, j)- elementWlij, the GC similarity matrix by
Wgwith the (i, j)-element Wgij, and the semantic similarity
matrix by Wswith the (i, j)-element Wsij.
1. Get theurl for service given by the PubMed.
2. Right click on solution Explorer. Click add Service
Reference.
3. Paste the url taken from web browser or the service url of
PubMed
4. Click on go Button and in the namespace textbox, change
the name as eUtils.
5. Now the proxy of service will get added in project. By
using that proxy, we can call all the methods needed to
retrieve the Biomedical Documents.
3.4 Proposed System Advantages
1. Proposed system made the most of the noisy constraints to
improve the clustering performance.
2. It was viewed that ML constraints were highly powerful and
CL constraints were very promising.
4. CONCLUSIONS
We have presented a semi supervised spectral clustering
method, which can incorporate both ML and CL constraints,
for integrating different information for biomedical document
clustering. We have emphasized that our idea behind this
project is to incorporate different type of similarities, i.e., the
LC, MS and GC similarities. Semi-supervised clustering
realizes this new idea, providing a more flexible framework
than a method of linearly combining different similarities.
FUTURE ENHANCEMENT
We present an application which is used to search particular
biomedical documents related to our need .In this project
Users are accessing biomedical documents from different
clusters. As documents are well clustered and the well filtered,
retrieving performance will be increased with a ranking along.
IJRET: International Journal of Research in Engineering and Technology eISSN: 2319-1163 | pISSN: 2321-7308
__________________________________________________________________________________________
Volume: 03 Issue: 03 | Mar-2014, Available @ http://www.ijret.org 147
REFERENCES
[1]. M. Krallinger, A. Valencia, and L. Hirschman, “Linking
genes to literature: Text mining, information extraction,and
retrieval applications for biology,” Genome Biol., vol. 9, no.
S2, pp. S8–S14, Sep. 2008.
[2]. D.Saravanan, Dr.S.Srinivasan, ”Matrix Based Indexing
Technique for Video Data “, International journal of Computer
Science”, 9(5): 534-542, 2013,pp 534-542.
[3]. D.Saravanan, Dr.S.Srinivasan, “Video Image Retrieval
Using Data Mining Techniques “Journal of Computer
Applications, Volume V, Issue No.1. Jan-Mar 2012. Pages39-
42. ISSN: 0974-1925.
[4]. D.Saravanan, Dr.S.Srinivasan, “ A proposed New
Algorithm for Hierarchical Clustering suitable for Video Data
mining.”, International journal of Data Mining and Knowledge
Engineering”, Volume 3,
[5]. A. Rzhetsky, M. Seringhaus, and M. Gerstein, “Seeking a
new biology through text mining,” Cell, vol. 134, no. 1, pp. 9–
13, Jul. 2008.
[6]. R. Baeza-Yates and B. Ribeiro-Neto, Modern Information
Retrieval. Reading, MA: Addison-Wesley, 1999. Number 9,
July 2011.Pages 569
[7]. M. Lee, W. Wang, and H. Yu, “Exploring supervised and
unsupervised methods to detect topics in biomedical text,”
BMC Bioinformat., vol. 7, no. 1, p. 140, Mar. 2006.
[8]. G. Salton and M. McGill, Introduction to Modern
Information Retrieval. New York: McGraw-Hill, 1983.
[9]. J. Lin and W. Wilbur, “PubMed related articles: A
probabilistic topic based model for content similarity,” BMC
Bioinformat., vol. 8, no. 1, p. 423, Oct. 2007.
[10]. T. Theodosiou, N. Darzentas, L. Angelis, and C.
Ouzounis, “PuReDMCL: A graph-based PubMed document
clustering methodology,” Bioinformatics, vol. 24, no. 17, pp.
1935–1941, Sep. 2008.
[11]. S. J. Nelson, M. Schopen, A. G. Savage, J. L. Schulman,
and N. Arluk, “The MeSH translation maintenance system:
Structure, interface design, and implementation,” in Proc.
MEDINFO, 2004, pp. 67–69.
[12]. I. Yoo, X. Hu, and I.-Y. Song, “Biomedical ontology
improves biomedical literature clustering performance: A
comparison study,” Int. J. Bioinformat. Res. Appl., vol. 3, no.
3, pp. 414–428, Sep. 2007.
[13]. D.Saravanan, Dr.S.Srinivasan, “Data Mining
Framework for Video Data”, In the Proc.of International
Conference on Recent Advances in Space Technology
Services & Climate Change (RSTS&CC-2010), held at
SathyabamaUniversity, Chennai, November 13-15,
2010.Pages 196-198.

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Clustering of medline documents using semi supervised spectral clustering

  • 1. IJRET: International Journal of Research in Engineering and Technology eISSN: 2319-1163 | pISSN: 2321-7308 __________________________________________________________________________________________ Volume: 03 Issue: 03 | Mar-2014, Available @ http://www.ijret.org 145 CLUSTERING OF MEDLINE DOCUMENTS USING SEMI-SUPERVISED SPECTRAL CLUSTERING AbinCherian1 , D.Saravanan2 , A.Jesudoss3 1 Department of Computer Application, 2, 3 Asst. Professor, MCA, Sathyabama University, Chennai-600119 Abstract We are considering: local-content (LC) information, global-content (GC) information from PubMed and MESH (medical subject heading-MS) for the clustering of bio-medical documents. The performances of MEDLINE document clustering are enhanced from previous methods by combining both the LC and GC. We propose a semi-supervised spectral clustering method to overcome the limitations of representation space of earlier methods. Keywords- document clustering, semi-supervised clustering, spectral clustering -------------------------------------------------------------------------***--------------------------------------------------------------------- 1. INTRODUCTION The major searching target over biomedical documents is MEDLINE, which is covering around 5600 life science journals published worldwide. We know that document clustering is grouping similar documents together and separating dissimilar documents automatically, contributes greatly to manage and organize literatures, navigate and locate searching results, and provide personalized information services. Only local-content (LC) information of documents from the data set to be clustered has been utilized for clustering. PubMed provides a set of related articles in the whole MEDLINE collection which usually compares words from the title, the abstract, and the medical subject heading for each MEDLINE document. 2. EXISTING SYSTEM There are two categories named constraint-based and distance based in the existing method. Constraint-based methods have user-provided labels or constraints to guide the algorithm towards a more appropriate data partitioning. By modifying the objective function for evaluating clustering’s, it is done. Thus it includes satisfying constraints, enforcing constraints during the clustering process, or initializing and constraining the clustering based on labeled examples. An existing clustering algorithm that uses a particular clustering distortion measure is employed in the distance-based category. It is trained to satisfy the labels or constraints in the supervised data here. 2.1 Existing System Technique K-mean’s clustering 1. Choose the number of different clusters, k. 2. Generate k clusters randomly and determine where the cluster centers. 3. Assign each point to the nearest cluster center, where we can define "nearest" wrt one of the distance measures discussed. 4. Recompute the new cluster centers. 5. Repeat the previous steps until some convergence criterion is met. 2.2 Existing System Drawbacks 1. True similarity would not be a simple linear relationship between different similarities. 2. The quality of similarity in a data set may not be same for all document pairs. Some pairs may be more reliable and need more attention. 3. Existing system couldn’t manage with a suitable weighting configuration to balance three or more different types of similarities in integrating them. 3. PROPOSED SYSTEM- To improve the clustering performance, Semi supervised spectral clustering algorithms are used. The prior knowledge to improve clustering is usually provided by labeled instances or, more typically, by two types of constraints, i.e., must-link (ML) and cannot-link (CL), where ML means that the two corresponding examples should be in the same cluster and CL means that the two corresponding examples which we are considering should not be in the same cluster. We know that the Spectral clustering is a well accepted method for clustering nodes over a graph or an adjacency matrix, where clustering is
  • 2. IJRET: International Journal of Research in Engineering and Technology eISSN: 2319-1163 | pISSN: 2321-7308 __________________________________________________________________________________________ Volume: 03 Issue: 03 | Mar-2014, Available @ http://www.ijret.org 146 a graph cut problem that can be solved by matrix trace optimization. 3.1 Overall Diagram 3.2 Scope of the Project By improving the performance, we have gone for alternative methods where user can search Biomedical text in our project. Usually, when user will search any text, it has to follow online databases. For searching about biomedical text, user can search documents from PubMed, Medline, PMC, Mesh, etc. These databases contain bulk amount of data. The retrieving of documents from these databases makes the performance slow. For this, we can provide option where to get documents, either from online databases or from our local database. We will make clustering of all our local database documents and can get documents from different clusters with the rank. 3.3 Proposed System Technique Semi-supervised spectral clustering We usually use Medline, PubMed or some other databases for searching biomedical related documents. In all these databases huge number of documents are available. While retrieving those documents, performance will get slow .Hence we can retrieve some selected documents in our local database. Thus the performance could be increased. And if we go for second time search, No need to go for online Database. Get it from our local database only. In our proposed algorithm, set of documents V (= {v1, v2, . . . ,vN}) has to be clustered. Let Sim(·, ·) be the function showing similarity between two inputs, and for example, Sim(M,M_) outputs similarity between two MeSH main headings M and M_.We denote the LC similarity matrix byWlwith the (i, j)- elementWlij, the GC similarity matrix by Wgwith the (i, j)-element Wgij, and the semantic similarity matrix by Wswith the (i, j)-element Wsij. 1. Get theurl for service given by the PubMed. 2. Right click on solution Explorer. Click add Service Reference. 3. Paste the url taken from web browser or the service url of PubMed 4. Click on go Button and in the namespace textbox, change the name as eUtils. 5. Now the proxy of service will get added in project. By using that proxy, we can call all the methods needed to retrieve the Biomedical Documents. 3.4 Proposed System Advantages 1. Proposed system made the most of the noisy constraints to improve the clustering performance. 2. It was viewed that ML constraints were highly powerful and CL constraints were very promising. 4. CONCLUSIONS We have presented a semi supervised spectral clustering method, which can incorporate both ML and CL constraints, for integrating different information for biomedical document clustering. We have emphasized that our idea behind this project is to incorporate different type of similarities, i.e., the LC, MS and GC similarities. Semi-supervised clustering realizes this new idea, providing a more flexible framework than a method of linearly combining different similarities. FUTURE ENHANCEMENT We present an application which is used to search particular biomedical documents related to our need .In this project Users are accessing biomedical documents from different clusters. As documents are well clustered and the well filtered, retrieving performance will be increased with a ranking along.
  • 3. IJRET: International Journal of Research in Engineering and Technology eISSN: 2319-1163 | pISSN: 2321-7308 __________________________________________________________________________________________ Volume: 03 Issue: 03 | Mar-2014, Available @ http://www.ijret.org 147 REFERENCES [1]. M. Krallinger, A. Valencia, and L. Hirschman, “Linking genes to literature: Text mining, information extraction,and retrieval applications for biology,” Genome Biol., vol. 9, no. S2, pp. S8–S14, Sep. 2008. [2]. D.Saravanan, Dr.S.Srinivasan, ”Matrix Based Indexing Technique for Video Data “, International journal of Computer Science”, 9(5): 534-542, 2013,pp 534-542. [3]. D.Saravanan, Dr.S.Srinivasan, “Video Image Retrieval Using Data Mining Techniques “Journal of Computer Applications, Volume V, Issue No.1. Jan-Mar 2012. Pages39- 42. ISSN: 0974-1925. [4]. D.Saravanan, Dr.S.Srinivasan, “ A proposed New Algorithm for Hierarchical Clustering suitable for Video Data mining.”, International journal of Data Mining and Knowledge Engineering”, Volume 3, [5]. A. Rzhetsky, M. Seringhaus, and M. Gerstein, “Seeking a new biology through text mining,” Cell, vol. 134, no. 1, pp. 9– 13, Jul. 2008. [6]. R. Baeza-Yates and B. Ribeiro-Neto, Modern Information Retrieval. Reading, MA: Addison-Wesley, 1999. Number 9, July 2011.Pages 569 [7]. M. Lee, W. Wang, and H. Yu, “Exploring supervised and unsupervised methods to detect topics in biomedical text,” BMC Bioinformat., vol. 7, no. 1, p. 140, Mar. 2006. [8]. G. Salton and M. McGill, Introduction to Modern Information Retrieval. New York: McGraw-Hill, 1983. [9]. J. Lin and W. Wilbur, “PubMed related articles: A probabilistic topic based model for content similarity,” BMC Bioinformat., vol. 8, no. 1, p. 423, Oct. 2007. [10]. T. Theodosiou, N. Darzentas, L. Angelis, and C. Ouzounis, “PuReDMCL: A graph-based PubMed document clustering methodology,” Bioinformatics, vol. 24, no. 17, pp. 1935–1941, Sep. 2008. [11]. S. J. Nelson, M. Schopen, A. G. Savage, J. L. Schulman, and N. Arluk, “The MeSH translation maintenance system: Structure, interface design, and implementation,” in Proc. MEDINFO, 2004, pp. 67–69. [12]. I. Yoo, X. Hu, and I.-Y. Song, “Biomedical ontology improves biomedical literature clustering performance: A comparison study,” Int. J. Bioinformat. Res. Appl., vol. 3, no. 3, pp. 414–428, Sep. 2007. [13]. D.Saravanan, Dr.S.Srinivasan, “Data Mining Framework for Video Data”, In the Proc.of International Conference on Recent Advances in Space Technology Services & Climate Change (RSTS&CC-2010), held at SathyabamaUniversity, Chennai, November 13-15, 2010.Pages 196-198.