DR.NAVIN AGRAWAL
Right Heart Catheterization
Left Ventricular Pressure
 Systole
 Isovolumetric contraction


From MV closure to AoV opening

 Ejection


Peak systolic
pressure

From AoV opening to AoV closure

 Diastole
 Isovolumetric relaxation


From AoV closure to MV opening

 Filling






From MV opening to MV closure
Early Rapid Phase
Slow Phase
Atrial Contraction (“a” wave”)

End diastolic
pressure
Peak systolic LV pressure
End diastolic LV pressure
Fixed aortic obstruction
Simultaneous pressure tracings from the left ventricle and the aorta in a patient with aortic
stenosis.

Brown J , Morgan-Hughes N J Contin Educ Anaesth Crit
Care Pain 2005;5:1-4
Continuing Education in Anaesthesia, Critical Care & Pain | Volume 5 Number 1 2005 © The
Board of Management and Trustees of the British Journal of Anaesthesia 2005
???
Left ventricular(LV) catheter pullback to aorta in a patient with hyperrtrophic
cardiomyopathy . There is a significant systolic gradient within the left ventricular
cavity and the LV outflow tract and aortic pressure waveforms exhibit a spike-and –
dome contour.
Left ventricular (LV) and femoral artery (FA) presure tracings in a woman with
hypertrophic cardiomyopathy and asymmertric septal hypertrophy illustration
the increase in gradient and develop a spike-and –dome configuration in the
arterial pressure waveform following an extrasystolic beat . Arterial pulse
pressure clearly narrows in postextrasystolic beat. The narrowing of pulse
pressure is known as Brockenbrough-Braunwald sign
Left ventricular(LV) and femoral artery (FA) pressure tracings . Valsalva
manuver producesa marked increase in the gradient , as well as a change in
the femoral arterial pressure waveform to a spike-and –dome configuration
Simultaneous left ventricular and aortic pressure tracings at rest and after provocation with
intravenous isoprenaline.

Serino W , Sigwart U Heart 1998;79:629-630

Copyright © BMJ Publishing Group Ltd & British Cardiovascular Society. All rights reserved.
Left ventricular (LV) and left brachial artery(LBA) pressure tracings in a 64year-old woman with hypertrophic caridomyopathy . A: The effect of a
spontaneous change from nodal rhythm to sinus rhythm. The short arrow
showed LVEDP. With restoration of sinus shythm abd a presumed decrease in
the obstruction. The loss of atrial kick in patients with a stiff ventricle leads to
an acute reduction in cardiac output.
Left ventricular (LV) micromanometer ad aortic (Ao) pressure tracings in a
68-year-old woman with advanced dilated cardiomyopathy . Marked
slowing of the rates of left ventricular pressure rise and fall give the LV
pressure tracing a triangular appearance
Hemodynamic Principles
PAW and LV Tracings during
Inspiration and Expiration

RV and LV Tracings during
Inspiration and Expiration
Hemodynamic Principles
Which of the following is the
most likely explanation for
these findings?
A. Chronic recurrent PE.
B. Constrictive pericarditis.
C. Atrial septal defect with a large shunt
and right heart failure.
D. Chronic pericarditis now presenting
with tamponade.
E. Chronic hepatitis with cirrhosis.

PAW and LV
Tracings during
Inspiration and
Expiration

RV and LV
Tracings during
Inspiration and
Expiration
Hemodynamic Principles
Which of the following is the
most likely explanation for
these findings?
A. Chronic recurrent PE.
B. Constrictive pericarditis.
C. Atrial septal defect with a large shunt
and right heart failure.
D. Chronic pericarditis now presenting
with tamponade.
E. Chronic hepatitis with cirrhosis.

PAW and LV
Tracings during
Inspiration and
Expiration

RV and LV
Tracings during
Inspiration and
Expiration
Hemodynamic Principles

A.
B.
C.
D.
E.

She has valvular aortic stenosis.
She has hypertrophic cardiomyopathy with obstruction.
She has an intraventricular pressure gradient.
She has a bicuspid aortic valve with mild stenosis.
She has a pressure gradient but it is likely an artifact.
Hemodynamic Principles

A.
B.
C.
D.
E.

She has valvular aortic stenosis.
She has hypertrophic cardiomyopathy with obstruction.
She has an intraventricular pressure gradient.
She has a bicuspid aortic valve with mild stenosis.
She has a pressure gradient but it is likely an artifact.
Dicrotic pressure changes
Dicrotic pressure changes
this part here is the dicrotic notch
Arterial Pressure Monitoring
Abnormalities in Central Aortic Tracing
 Spike and dome configuration
 Hypertrophic obstructive cardiomyopathy

Spike

Dome

Davidson CJ, et al. Cardiac Catheterization. In: Heart Disease: A Textbook of Cardiovascular Medicine,
Edited by E. Braunwald, 5th ed. Philadelphia: WB Saunders Company, 1997
Right Heart Catheterization
Left Ventricular Pressure
 Systole
 Isovolumetric contraction


From MV closure to AoV opening

 Ejection


Peak systolic
pressure

From AoV opening to AoV closure

 Diastole
 Isovolumetric relaxation


From AoV closure to MV opening

 Filling






From MV opening to MV closure
Early Rapid Phase
Slow Phase
Atrial Contraction (“a” wave”)

End diastolic
pressure
Peak systolic LV pressure
End diastolic LV pressure
Fixed aortic obstruction
Simultaneous pressure tracings from the left ventricle and the aorta in a patient with aortic
stenosis.

Brown J , Morgan-Hughes N J Contin Educ Anaesth Crit
Care Pain 2005;5:1-4
Continuing Education in Anaesthesia, Critical Care & Pain | Volume 5 Number 1 2005 © The
Board of Management and Trustees of the British Journal of Anaesthesia 2005
???
Left ventricular(LV) catheter pullback to aorta in a patient with hyperrtrophic
cardiomyopathy . There is a significant systolic gradient within the left ventricular
cavity and the LV outflow tract and aortic pressure waveforms exhibit a spike-and –
dome contour.
Arterial Pressure Monitoring
Central Aortic and Peripheral Tracings
 Pulse pressure =

Systolic – Diastolic
 Mean aortic pressure
typically < 5 mm Hg
higher than mean
peripheral pressure
 Aortic waveform varies
along length of the aorta
 Systolic wave increases in amplitude while diastolic wave

decreases
 Mean aortic pressure constant
 Dicrotic notch less apparent in peripheral tracing
Davidson CJ, et al. Cardiac Catheterization. In: Heart Disease: A Textbook of Cardiovascular Medicine,
Edited by E. Braunwald, 5th ed. Philadelphia: WB Saunders Company, 1997
PWV
stiffer arteries → increased PWV
→ earlier arrival of reflected waves →
augmentation of systolic rather than
diastolic pressure→increased pulse pressure
Dehydration-Hypovolemia
Effects of respiration
ANACROTIC
SHOULDER
Pulsus paradoxus
Pulsus alternans
Pericardial effusion
Cardiomyopathy
CHF
Advancing Your Right Heart
Catheter
 Advance the SGC to

about 20cm and inflate
the balloon tip.
 Initial chamber  the
right atrium.
 Initial pressure waveform
3 positive deflections, the
a, c and v waves
 There will be an x and y
descent
Right Atrial Pressure Tracing
 a wave –atrial systole
 c wave – occurs with the

closure of the tricuspid
valve and the initiation of
atrial filling
 v wave – occurs with
blood filling the atrium
while the tricuspid valve
is closed
Timing of the positive deflections
 a wave – occurs after
the P wave (60-80
msec)during the PR
interval
 c wave – when present
occurs at the end of the
QRS complex (RST
junction)
 v wave – Peak occurs
after the T wave
Right Atrial Chamber
1. Height of the v wave

atrial compliance
volume of blood returning
2. Height of the a wave
The pressure needed to
eject forward blood flow

 The v wave is usually smaller

than the a wave in the right
atrium
Right Heart Pressures Tracings
Right Atrial Chamber
1. Height of the v wave

atrial compliance
volume of blood returning
2. Height of the a wave
The pressure needed to
eject forward blood flow

 The v wave is usually smaller

than the a wave in the right
atrium
Right atrial hemodynamic pathology
 Elevated a wave
 Tricuspid stenosis
 Decreased RV

compliance


e.g. pulm htn, pulmonic
stenosis

 Cannon a wave
 AV asynchrony –

atrium contracts against
a closed tricuspid valve


e.g. AVB, Vtach

X descent
Prominent –Tamponade,RV
ischemia,(ASD)
Absent – Atrial
arrhythmias,TR,RA ischemia

 Absent a wave

 Atrial fibrillation or

standstill
 Atrial flutter

 Elevated v wave
 Tricuspid regurgitation
 RV failure
 Reduced atrial compliance


e.g. restrictive myopathy

Y descent
Prominent –CCP/RCM/TR
Absent – TS/Tamponade/RV
ischemia
Right atrial hemodynamic pathology

Note the Cannon a wave that is
occurring during AV dysynchrony
– atrial contraction is occurring
against a closed tricuspid valve.

Note the large V wave that
occurs with Tricuspid
regurgitation
Hemodynamic Pathology
 Tricuspid Stenosis
 Large jugular venous a

waves on noted on
exam
 Notable elevated a
wave with the presence
of a diastolic gradient >5mmHg gradient is
considered signficant
Prominent Rt V wave
 V> 15 mmHg
 Difference of V and RA

mean >5 mmHg
 Ration of V to RA
mean>1.5
Advancing Your Right Heart
Catheter
 Continue advancing the catheter
into the right ventricle
 The right and left ventricular

pressure tracings are similar.
 The right ventricular has a shorter
duration of systole
 Diastolic pressure in the right
ventricle is characterized by an
early rapid filling phase, then slow
filling phase followed by the atrial
kick or a wave

a
Normal RV waveform artifact
 Note the notch on the
top of RV pressure
waveform
 This represents

“ringing” of a fluid-filled
catheter
 Ringing can also be
noted on the diastolic
portion of the waveform
Advancing Your Right Heart
Catheter
 Advancing out the RVOT to the
pulmonary artery
 There is a systolic wave indicating

ventricular contraction followed by
closure of the pulmonic valve and
then a gradual decline in pressure
until the next systolic phase.
 Closure of the pulmonic valve is
indicated by the dicrotic notch
Timing of the PA pressure
 Peak systole correlates
with the T wave
 End diastole correlates
with the QRS complex
Hemodynamic Pathology
 Pulmonic Stenosis
 Notable large gradient

across the pulmonic
valve during PA to RV
pullback.
 Notable extreme
increases in RV systolic
pressures and a
damped PA pressure
Right atrial hemodynamic pathology

Note the Cannon a wave that is
occurring during AV dysynchrony
– atrial contraction is occurring
against a closed tricuspid valve.

Note the large V wave that
occurs with Tricuspid
regurgitation
Hemodynamic Pathology
 Tricuspid Stenosis
 Large jugular venous a

waves on noted on
exam
 Notable elevated a
wave with the presence
of a diastolic gradient >5mmHg gradient is
considered signficant
Prominent Rt V wave
 V> 15 mmHg
 Difference of V and RA

mean >5 mmHg
 Ration of V to RA
mean>1.5
Hemodynamic Pathology

Mitral Stenosis
This patient underwent mitral valvuloplasty resulting in a reduction of
the resting gradient by 10mmHg and an increase in CO from 3.7 to
5.5LPM and a valve area from about 1.1 to 2.9 cm2
E
F
G
A
B
C
D
E
F
G
H
I

-PCWP tracing
J

-PCWP
K
L
M
N
NORMAL PRESSURE TRESSINGS – RA, RV , PA, PCWP
peak

100

a

0
Dip

NORMAL PRESSURE TRACING – Ventricle.
Peak systolic

end diastolic

NORMAL ARTERIAL PRESSURE TRACINGS
Kussmaul’s Sign

CATHSAP6: Coronary Angiography and Intervention
Mitral stenosis with 20 mm
gradient. Atrial fibrillation.
Note slow “y” descent and lack
of “a” waves (atrial fib.).

Name this pathology.
97
Probable Mitral
Regurgitation.
Large “v” waves, which could also
be due to atrial fibrillation or
CHF.

Name this pathology.
98
40
Right atrium

20

0
40

20

0

Right ventricle
40

20

0

Pulmonary artery
40

20

0

Pulmonary capillary wedge
NORMAL PRESSURE
TRACINGS – LA , LV ,
AORTA
Collection of cath tracings by navin
Collection of cath tracings by navin

Collection of cath tracings by navin

  • 1.
  • 2.
    Right Heart Catheterization LeftVentricular Pressure  Systole  Isovolumetric contraction  From MV closure to AoV opening  Ejection  Peak systolic pressure From AoV opening to AoV closure  Diastole  Isovolumetric relaxation  From AoV closure to MV opening  Filling     From MV opening to MV closure Early Rapid Phase Slow Phase Atrial Contraction (“a” wave”) End diastolic pressure
  • 3.
  • 4.
  • 5.
  • 6.
    Simultaneous pressure tracingsfrom the left ventricle and the aorta in a patient with aortic stenosis. Brown J , Morgan-Hughes N J Contin Educ Anaesth Crit Care Pain 2005;5:1-4 Continuing Education in Anaesthesia, Critical Care & Pain | Volume 5 Number 1 2005 © The Board of Management and Trustees of the British Journal of Anaesthesia 2005
  • 7.
  • 8.
    Left ventricular(LV) catheterpullback to aorta in a patient with hyperrtrophic cardiomyopathy . There is a significant systolic gradient within the left ventricular cavity and the LV outflow tract and aortic pressure waveforms exhibit a spike-and – dome contour.
  • 9.
    Left ventricular (LV)and femoral artery (FA) presure tracings in a woman with hypertrophic cardiomyopathy and asymmertric septal hypertrophy illustration the increase in gradient and develop a spike-and –dome configuration in the arterial pressure waveform following an extrasystolic beat . Arterial pulse pressure clearly narrows in postextrasystolic beat. The narrowing of pulse pressure is known as Brockenbrough-Braunwald sign
  • 10.
    Left ventricular(LV) andfemoral artery (FA) pressure tracings . Valsalva manuver producesa marked increase in the gradient , as well as a change in the femoral arterial pressure waveform to a spike-and –dome configuration
  • 11.
    Simultaneous left ventricularand aortic pressure tracings at rest and after provocation with intravenous isoprenaline. Serino W , Sigwart U Heart 1998;79:629-630 Copyright © BMJ Publishing Group Ltd & British Cardiovascular Society. All rights reserved.
  • 12.
    Left ventricular (LV)and left brachial artery(LBA) pressure tracings in a 64year-old woman with hypertrophic caridomyopathy . A: The effect of a spontaneous change from nodal rhythm to sinus rhythm. The short arrow showed LVEDP. With restoration of sinus shythm abd a presumed decrease in the obstruction. The loss of atrial kick in patients with a stiff ventricle leads to an acute reduction in cardiac output.
  • 13.
    Left ventricular (LV)micromanometer ad aortic (Ao) pressure tracings in a 68-year-old woman with advanced dilated cardiomyopathy . Marked slowing of the rates of left ventricular pressure rise and fall give the LV pressure tracing a triangular appearance
  • 14.
    Hemodynamic Principles PAW andLV Tracings during Inspiration and Expiration RV and LV Tracings during Inspiration and Expiration
  • 15.
    Hemodynamic Principles Which ofthe following is the most likely explanation for these findings? A. Chronic recurrent PE. B. Constrictive pericarditis. C. Atrial septal defect with a large shunt and right heart failure. D. Chronic pericarditis now presenting with tamponade. E. Chronic hepatitis with cirrhosis. PAW and LV Tracings during Inspiration and Expiration RV and LV Tracings during Inspiration and Expiration
  • 16.
    Hemodynamic Principles Which ofthe following is the most likely explanation for these findings? A. Chronic recurrent PE. B. Constrictive pericarditis. C. Atrial septal defect with a large shunt and right heart failure. D. Chronic pericarditis now presenting with tamponade. E. Chronic hepatitis with cirrhosis. PAW and LV Tracings during Inspiration and Expiration RV and LV Tracings during Inspiration and Expiration
  • 17.
    Hemodynamic Principles A. B. C. D. E. She hasvalvular aortic stenosis. She has hypertrophic cardiomyopathy with obstruction. She has an intraventricular pressure gradient. She has a bicuspid aortic valve with mild stenosis. She has a pressure gradient but it is likely an artifact.
  • 18.
    Hemodynamic Principles A. B. C. D. E. She hasvalvular aortic stenosis. She has hypertrophic cardiomyopathy with obstruction. She has an intraventricular pressure gradient. She has a bicuspid aortic valve with mild stenosis. She has a pressure gradient but it is likely an artifact.
  • 19.
  • 20.
    Dicrotic pressure changes thispart here is the dicrotic notch
  • 21.
    Arterial Pressure Monitoring Abnormalitiesin Central Aortic Tracing  Spike and dome configuration  Hypertrophic obstructive cardiomyopathy Spike Dome Davidson CJ, et al. Cardiac Catheterization. In: Heart Disease: A Textbook of Cardiovascular Medicine, Edited by E. Braunwald, 5th ed. Philadelphia: WB Saunders Company, 1997
  • 23.
    Right Heart Catheterization LeftVentricular Pressure  Systole  Isovolumetric contraction  From MV closure to AoV opening  Ejection  Peak systolic pressure From AoV opening to AoV closure  Diastole  Isovolumetric relaxation  From AoV closure to MV opening  Filling     From MV opening to MV closure Early Rapid Phase Slow Phase Atrial Contraction (“a” wave”) End diastolic pressure
  • 24.
  • 25.
  • 26.
  • 27.
    Simultaneous pressure tracingsfrom the left ventricle and the aorta in a patient with aortic stenosis. Brown J , Morgan-Hughes N J Contin Educ Anaesth Crit Care Pain 2005;5:1-4 Continuing Education in Anaesthesia, Critical Care & Pain | Volume 5 Number 1 2005 © The Board of Management and Trustees of the British Journal of Anaesthesia 2005
  • 28.
  • 29.
    Left ventricular(LV) catheterpullback to aorta in a patient with hyperrtrophic cardiomyopathy . There is a significant systolic gradient within the left ventricular cavity and the LV outflow tract and aortic pressure waveforms exhibit a spike-and – dome contour.
  • 32.
    Arterial Pressure Monitoring CentralAortic and Peripheral Tracings  Pulse pressure = Systolic – Diastolic  Mean aortic pressure typically < 5 mm Hg higher than mean peripheral pressure  Aortic waveform varies along length of the aorta  Systolic wave increases in amplitude while diastolic wave decreases  Mean aortic pressure constant  Dicrotic notch less apparent in peripheral tracing Davidson CJ, et al. Cardiac Catheterization. In: Heart Disease: A Textbook of Cardiovascular Medicine, Edited by E. Braunwald, 5th ed. Philadelphia: WB Saunders Company, 1997
  • 33.
    PWV stiffer arteries →increased PWV → earlier arrival of reflected waves → augmentation of systolic rather than diastolic pressure→increased pulse pressure
  • 34.
  • 35.
  • 36.
  • 37.
  • 38.
  • 40.
    Advancing Your RightHeart Catheter  Advance the SGC to about 20cm and inflate the balloon tip.  Initial chamber  the right atrium.  Initial pressure waveform 3 positive deflections, the a, c and v waves  There will be an x and y descent
  • 41.
    Right Atrial PressureTracing  a wave –atrial systole  c wave – occurs with the closure of the tricuspid valve and the initiation of atrial filling  v wave – occurs with blood filling the atrium while the tricuspid valve is closed
  • 42.
    Timing of thepositive deflections  a wave – occurs after the P wave (60-80 msec)during the PR interval  c wave – when present occurs at the end of the QRS complex (RST junction)  v wave – Peak occurs after the T wave
  • 43.
    Right Atrial Chamber 1.Height of the v wave atrial compliance volume of blood returning 2. Height of the a wave The pressure needed to eject forward blood flow  The v wave is usually smaller than the a wave in the right atrium
  • 44.
  • 46.
    Right Atrial Chamber 1.Height of the v wave atrial compliance volume of blood returning 2. Height of the a wave The pressure needed to eject forward blood flow  The v wave is usually smaller than the a wave in the right atrium
  • 47.
    Right atrial hemodynamicpathology  Elevated a wave  Tricuspid stenosis  Decreased RV compliance  e.g. pulm htn, pulmonic stenosis  Cannon a wave  AV asynchrony – atrium contracts against a closed tricuspid valve  e.g. AVB, Vtach X descent Prominent –Tamponade,RV ischemia,(ASD) Absent – Atrial arrhythmias,TR,RA ischemia  Absent a wave  Atrial fibrillation or standstill  Atrial flutter  Elevated v wave  Tricuspid regurgitation  RV failure  Reduced atrial compliance  e.g. restrictive myopathy Y descent Prominent –CCP/RCM/TR Absent – TS/Tamponade/RV ischemia
  • 48.
    Right atrial hemodynamicpathology Note the Cannon a wave that is occurring during AV dysynchrony – atrial contraction is occurring against a closed tricuspid valve. Note the large V wave that occurs with Tricuspid regurgitation
  • 49.
    Hemodynamic Pathology  TricuspidStenosis  Large jugular venous a waves on noted on exam  Notable elevated a wave with the presence of a diastolic gradient >5mmHg gradient is considered signficant
  • 50.
    Prominent Rt Vwave  V> 15 mmHg  Difference of V and RA mean >5 mmHg  Ration of V to RA mean>1.5
  • 51.
    Advancing Your RightHeart Catheter  Continue advancing the catheter into the right ventricle  The right and left ventricular pressure tracings are similar.  The right ventricular has a shorter duration of systole  Diastolic pressure in the right ventricle is characterized by an early rapid filling phase, then slow filling phase followed by the atrial kick or a wave a
  • 52.
    Normal RV waveformartifact  Note the notch on the top of RV pressure waveform  This represents “ringing” of a fluid-filled catheter  Ringing can also be noted on the diastolic portion of the waveform
  • 53.
    Advancing Your RightHeart Catheter  Advancing out the RVOT to the pulmonary artery  There is a systolic wave indicating ventricular contraction followed by closure of the pulmonic valve and then a gradual decline in pressure until the next systolic phase.  Closure of the pulmonic valve is indicated by the dicrotic notch
  • 54.
    Timing of thePA pressure  Peak systole correlates with the T wave  End diastole correlates with the QRS complex
  • 55.
    Hemodynamic Pathology  PulmonicStenosis  Notable large gradient across the pulmonic valve during PA to RV pullback.  Notable extreme increases in RV systolic pressures and a damped PA pressure
  • 56.
    Right atrial hemodynamicpathology Note the Cannon a wave that is occurring during AV dysynchrony – atrial contraction is occurring against a closed tricuspid valve. Note the large V wave that occurs with Tricuspid regurgitation
  • 57.
    Hemodynamic Pathology  TricuspidStenosis  Large jugular venous a waves on noted on exam  Notable elevated a wave with the presence of a diastolic gradient >5mmHg gradient is considered signficant
  • 58.
    Prominent Rt Vwave  V> 15 mmHg  Difference of V and RA mean >5 mmHg  Ration of V to RA mean>1.5
  • 59.
    Hemodynamic Pathology Mitral Stenosis Thispatient underwent mitral valvuloplasty resulting in a reduction of the resting gradient by 10mmHg and an increase in CO from 3.7 to 5.5LPM and a valve area from about 1.1 to 2.9 cm2
  • 60.
  • 61.
  • 62.
  • 64.
  • 65.
  • 66.
  • 67.
  • 68.
  • 69.
  • 70.
  • 71.
  • 72.
  • 73.
  • 74.
  • 75.
  • 76.
  • 77.
  • 78.
    NORMAL PRESSURE TRESSINGS– RA, RV , PA, PCWP
  • 90.
  • 91.
    Peak systolic end diastolic NORMALARTERIAL PRESSURE TRACINGS
  • 92.
    Kussmaul’s Sign CATHSAP6: CoronaryAngiography and Intervention
  • 97.
    Mitral stenosis with20 mm gradient. Atrial fibrillation. Note slow “y” descent and lack of “a” waves (atrial fib.). Name this pathology. 97
  • 98.
    Probable Mitral Regurgitation. Large “v”waves, which could also be due to atrial fibrillation or CHF. Name this pathology. 98
  • 103.
  • 104.
  • 105.
  • 106.
  • 108.