This document compares the static and dynamic seismic analysis of multi-story reinforced concrete buildings using the ETAB software. Two buildings, a 10-story and 25-story structure, located in seismic zone III are analyzed using the equivalent static analysis and response spectrum methods. Results show that the response spectrum method produces lower story drift, displacement, axial loads, and bending moments compared to the equivalent static analysis method. For the 10-story building, story drift is up to 25% lower, displacements are up to 26% lower, axial loads on columns are up to 8% lower, and beam end bending moments are up to 7% lower using the response spectrum method. Similarly, for the 25-story building, the response spectrum method