Death By Eating

Detoxing Heavy Metals Integrative Approaches in Medicine Harold Ravins, DDS The Center for Holistic Dentistry

Advances in Holistic Dentistry Find hidden infections in the mouth Not considered usual dental problems Not the primary indicator of a health problem How? Good quality X-rays Bite analysis T-scan Comprehensive exam Bio-electrical Impedance Dental acupuncture Heavy metal fecal test Energetic testing Other detection methods

Determination of Hg Toxicity Practical experience 200 patients tested for heavy metals 99% showed toxic levels of Hg Discuss harmful effects of Hg to patients Give them educational literature Recommend fecal test Patients usually decide for themselves to have amalgams removed

Mercury Situation in Dentistry ADA claims no scientific proof of leakage into the body However: FDA agrees that Hg is very toxic Dentists are required comply with hazardous waste remove for Hg Test show high levels with amalgams Amalgams banned in Europe $2500 fine by EPA if office windows are opened

Shouldn’t we be concerned about the established relationship between toxins, cancer, heart disease, and other chronic illnesses?... Especially now that cancer is the #1 cause of death and the #1 cause of death among our children ages 1-15! Why are we not addressing TOXINS! Toxins?

What can we do? Inform ourselves as health care providers what toxins are and how they damage biological systems Develop ways to evaluate, measure and inform our patients Develop simple, safe and effective means to do this Let’s practice healing … Not Medicating

In the News 45 States Have Issued Mercury Advisories: coal-fired power plants Source: News-Leader.com – Quoted from the EPA and Department of Natural Resources Mercury and Fish Advisories Issued for Nine More Waterways Source: De Ridder Beauregard Daily News –Quoted from The Louisiana Department of Health and Hospitals Environmental Quality Dangerous Lead Levels Found in More Homes Source: Cincinnati Enquirer – Quoted from the EPA Lead Linked to Premature Deaths in Adults: Early Exposure = 46% Higher Mortality Source: The Baltimore Sun – Quoted from the CDC

In the News (Cont’d) California Sues Over Heavy-Metal Fish Source: Business Report – Quoted from the California Attorney General Lead Poisoning Alert Source: pediatrics.about.com – Quoted from the FDA Mercury Air Level is Worry for Ohio Source: Akron Beacon Journal – Quoted from the EPA EPA Doubles Estimates of Children with Mercury in Blood Source: Access North Georgia – Quoted from the EPA Mercury List Longer Each Year Source: The News-Press – Quoted from Dept. of Environmental Protection

In the News (Cont’d) CDC Vaccine Data Leads Scientists to Shocking Discovery: Possible Autism/Neurological Link Source: Yahoo News – Quoted from the CDC Chromated Copper Arsenate: CCA-Treated Lumber Poses Danger from Arsenic Toxicol Sci. 2004 Jun;79(2):287-95 EPA: Amount of Toxins in Air, Water and Land Increased at Record Rate… Source: Axis of Logic – Quoted from the EPA FDA Warns Pregnant Women to Limit Tuna Richard Simmons -Los Angeles Times 3/2004

Major Heavy Metal Toxins Mercury Lead Cadmium Aluminum Arsenic Nickel

Metal Toxicity Mechanisms Neurotoxic: damage brain structures; lower IQ; down-regulates dopamine activity Nephrotoxic Immune dysregulation Cardiovascular Bone & tissue deposits Dysbiosis; fungal mycotoxins Endocrine disruption; thyroid, adrenal, sex h Cognitive problems; ADHD, Alz, depression Metabolic dysregulation; energy decline, etc

Health Care Professionals Education for your patients’ sake A plea to stay abreast of new modalities for patient care Be informed of what our industrialized society is doing to our patients’ health Be open to complementary treatments New diagnostic tests to assess toxicity Know that your patients are more informed and asking for our help for treatment and prevention of toxic pollutants Look toward innovation, science, research and validation of the best methods to give your patients what they demand

Time-Lapse Microphotography of Toxic Effects on Human Cells Normal Cell Growth Toxic Cell Damage and Death

Lead-induced Hypertension: Role of Oxidative Stress Chronic, low-level lead exposure causes hypertension in both animals and humans Inactivation of endogenous nitric oxide Reactive oxygen species (ROS) lowers enzyme activity Functional deficiency in nitric oxide Increase sympathetic activity & plasma norepinephrine Lead-induced inhibition of vascular smooth muscle ACE, angiotensin II, aldosterone, thromboxane Ref: Vaziri ND, “Lead-induced Hypertension: Role of Oxidative Stress,” Curr Hypertens Rep. 2004 Aug;6(4):314-20

Random Blood Sampling of Dr. Ellithorpe’s Patients: Presence Excessively High Heavy Metals Percent of Patients N=251

Sources of Toxic Metals - Aluminum Eating small amounts of aluminum in food Breathing aluminum dust in air Drinking contaminated water near: Waste Sites Manufacturing plants Areas naturally high in aluminum Antacids Cooking utensils - minimal Source: Agency for Toxic Substances & Disease Registry

Sources of Toxic Metals - Arsenic Eating food, drinking water or breathing air containing arsenic Breathing contaminated air Breathing sawdust, burning smoke Living near hazardous waste sites Living near high levels of arsenic in rock Source: Agency for Toxic Substances & Disease Registry

Sources of Toxic Metals - Cadmium Breathing contaminated air Battery manufacturing Metal soldering or welding Eating foods containing cadmium: Shellfish, Liver, Kidney meats Breathing cigarette smoke Drinking contaminated water Breathing contaminated air Burning of fossil fuels, municipal waste Source: Agency for Toxic Substances & Disease Registry

Sources of Toxic Metals - Mercury Eating fish or shellfish Breathing vapors from: Spills, incinerators, industry Dental work, medical treatments Breathing contaminated air or skin contact: Dental, health services, chemical, other industries using mercury Source: Agency for Toxic Substances & Disease Registry

Sources of Toxic Metals - Lead Eating food, drinking water that contains lead Lead base paints Working where lead is used Health care products containing lead Hobbies which lead is used: Glass staining Source: Agency for Toxic Substances & Disease Registry

Global Chronic Low Level Metal Toxicity Recognized by: US Environmental Protection Agency (EPA) Food & Drug Administration (FDA) Centers for Disease Control (CDC) State Health Departments Treatment standards are needed Preventative measures Comprehensive medicine with proven results Reduction of crisis management

There are NO Safe Levels of Heavy Metals Low levels are becoming dangerous Low levels accumulate Low levels become stored Low levels become higher Multiple toxins compound the danger

Death Rates of Participants with Low Pb Levels in NHANES III Survey Percent Increase in Mortality Ref: Lustberg, Mark and Silbergeld, Ellen. Blood lead levels and mortality. Arch Intern Med, 2002, 162: 2443-2449 Blood Lead Levels ( µg/dL)

NHANES-III Survey Results Estimated 29 million people (15% of adult population over age 20) had Pb levels of at least 20 µg/dL from 1976-1980. 30 µg/dL Pb is considered toxic Ref: Lustberg, Mark and Silbergeld, Ellen. Blood lead levels and mortality. Arch Intern Med, 2002, 162: 2443-2449 .

Heavy Metals Heavy metals and other toxins cause cell membrane damage through the production of free radicals and oxidative stress.

Human Cell Schematic Cell Membrane Mitochondria Nucleus Cytoplasm

The cell contains all of Life’s processes. Of particular importance Is the mitochondria , which are the sites of energy production

The Cell and Mitochondria Membrane

Cell Membrane Mitochondria Membrane (Outer) Mitochondria Membrane (Inner)

Oxidative Damage to Cell Membranes Healthy Membrane Oxidative Stress Damage

Chelation Therapy Modes DMPS; IV, transdermal DMSA; oral Penicillinamine EDTA IV Oral Rectal Suppositories Others Oral supplements

Recommended Modality CaNa 2 EDTA Chelation Suppositories

Detoxamin ® CaNa 2 EDTA Suppositories

Why CaNa 2 EDTA Suppositories? Non-invasive Safe Broad specificity metal chelation Easy to use Low cost Less time consuming Convenient

CaNa 2 EDTA Chelation (Detoxamin) FDA approved for lead detoxification Also chelates other metals Suppository form Can be used in combination with IV, oral, transdermal, topical or as stand alone therapy IV Chelation Expensive Time consuming – 3-5 hours Invasive Greater risk

Pharmacokinetic Pre-clinical Results Over 8 hours 1.5 hours Half-Life 13.6 3.7 Blood to Tissue Ratio 36.3 % 100% Absolute Bioavailability Rectal (Suppositories) Intravenous

Specimen Collection Summary Pre-Detoxamin CaNa 2 -EDTA Suppositories Comprehensive stool analysis with Fecal Metals analysis Post-Detoxamin CaNa 2 -EDTA Suppositories Comprehensive Stool Analysis with Fecal Metals analysis after the 90 th suppository

Protocol Challenge for Heavy Metals 1.5 gm CaNa 2 EDTA Detoxamin suppositories 2 - 750 mg suppositories at night Fecal test - send to Doctors Data, St Charles, Illinois, ( 800-323-2784) Typically several heavy metals are present Average 6-12 Elevated 1-4 Recommend Detoxamin suppositories at bedtime Monday through Thursday nights x 90 suppositories Consistently used – will be finished in 6 months

Protocol (Cont’d) Repeat the same challenge and compare results Maintenance – 1 suppository last 5 nights of each month Recommend Vitamin/mineral supplement RepairACell or one of your choice

Why Detoxamin: CaNa 2 EDTA Suppositories? Clinically proven Unparalleled safety EDTA - US FDA approved for Pb detox Consumer friendly Low cost Can treat large patient population, home use Less time consuming than IV chelation Broad specificity metal chelation Easy to use and convenient Effective in children, adolescents and adults

Comparison of IV Chelation and Detoxamin Yes Yes Clinically proven No Yes Easy to administer No Yes Greater risk No Yes Expensive No Yes Time consuming No Yes Invasive Detoxamin IV Chelation

Detoxamin Safety Comprehensive Metabolic Panel Albumin - Total Protein Total Bilirubin - Sodium Calcium - AST (SGOT) Chloride - Urea Nitrogen (BUN) Creatinine, Serum - Bicarbonate (CO 2) Glucose - ALT (SGPT) Alkaline Phosphatase - C-Reactive Protein Potassium No statistical difference in above lab parameters between pre and post treatment with Detoxamin in all subjects

Practical Clinical Case Study 55 y/o • W • F • 131 lbs. • School Teacher • Chronic LBP • Fatigue • Hypothyroid Outcome: 7/04 – Excellent energy • Exercise 3x/day – water aerobics • Back pain stable • Reduced need for medications. Patient K.M . Ni Pb Hg Cd Date 13 27 18 1.0 2/05 17 27 2.6 1.0 2/04 9.5 43 30 1.7 5/03

Practical Clinical Case Study 42 y/o • W • F • 145 lbs. • Photographer • Fibromyalgia • Chronic Fatigue • Hypothyroid Outcome: 11/04 – Energy good • Exercises daily (45 min.) with mild to moderate pain of fibromyalgia • Increased daily activities F.K. Ni Hg Pb Cd Ar Date 18 8.9 12 3.2 45 5/03 25 15 7.4 2.1 4.5 12/02 49 24 20 2.5 220 8/02

Practical Clinical Case Study 52 y/o • M • 175 lbs. • Electrician • Chronic Anxiety Panic Attacks • Hypertension • LBP Outcome: 10/04 – Anxiety greatly improved • Reduced need for auxiolytic medication • Improved BP • Reduced anti-hypertensive medication • LBP improved • Exercises daily (30 min.) Patient M.O. 7.7 16 3.8 0.7 5/04 1.6 20 9.8 1.4 10/03 12 12 1.6 1.0 12/04 3.6 18 4.4 0.9 2/03 Ni Pb Hg Cd Date 8.4 27 5.2 1.2 10/02

Detoxamin Excretion of Toxic Metals in Feces * Significantly different from Day 0 (p<0.05) Mean Values mg/kg

Detoxamin Excretion of Toxic Metals in Feces (Cont’d) Mean Value mg/kg * Significantly different from Day 0 (p<0.05) Nickel

Detoxamin Excretion of Toxic Metals in Urine Mean Values µg/g creatinine * Significantly different from Day 0 (p<0.05) * * * * * *

Detoxamin Safety (Cont’d) Observations within study Dosage form is gentle Little biological burden In general, very well tolerated Historical events Over 450,000 doses administered within the past five years Minor complaints with first few applications Loose stools Rectal gas Headache Lethargy Joint pain

Detoxamin Clinical Pilot Study Summary Significant excretions observed Fecal Ar, Pb, Cd, Ni Urine Ar, Pb, Hg, Cd, Ni Average change in pre and post DMSA Fifty percent for Al, Ar, Pb, Hg, Ni No difference with Cd

Effects of Detoxamin on Elevated Lead Urine Levels in Children In connection with Columbia and Fordham U Purpose: To demonstrate gradual lead reduction in blood and urine Conducted in Dominican Republic Residential neighborhood near battery recycling plant 20 children identified with blood levels over 10 µg/dL Initial mean blood determination of 66.6 µg/dL Pb Note: Blood levels of > 10 µg/dL are of CDC concern Treatment with 1000mg Detoxamin suppositories

Effects of Detoxamin on Elevated Lead Urine Levels in Children 325.6 µg/dL Treatment Day N=20

Effects of Detoxamin on Elevated Lead Urine Levels in Children - Summary Significant excretion of Pb was observed after only one initial dose of Detoxamin (325.6 µg/dL or 78 times more Pb excreted above baseline of 4.2µg/dL) Gradual Pb excretion occurred continually of a 30 day period

Detoxamin Instructions for use Administration Self application rectal suppository One per evening or one every other evening Evacuate bowels before application Three to six months duration Recommendations Eat evening meals 3-4 hours prior to Detoxtamin Protein rich with low sugar content Take quality multi-vitamin/mineral supplement in AM Maintenance Six Detoxamin suppositories per month For more information call 1-877-656-4553 – www.Detoxamin.com

Comparison of IV Chelation and CaNa 2 EDTA Suppositories Yes Yes FDA approved Yes Yes Clinically proven Yes Yes Broad spectrum metal removal Yes No Increased safety Yes No Inexpensive Yes No Quick and easy to use Yes No Non-Invasive Rectal Suppositories IV Chelation

Death By Eating

More Related Content

Similar to Death By Eating

More from hiratufail

Recently uploaded

Death By Eating