The talk by Tomasz Kowal highlights the synergy between Elixir and Elm for web application development, emphasizing concepts like single source of truth and one-directional flows. It discusses the unique strengths of each language, particularly Elixir's focus on web applications and fault tolerance via Erlang, and Elm's static typing and simplicity for browser-based programming. The presentation suggests that using multiple programming languages can enhance problem-solving in interactive web environments.