Evidence-Based  Back Pain Management Sohail Bajammal, MBChB, MSc, FRCS(C), PhD(c) Assistant Professor of Orthopaedics May 30, 2010
What got me into EBM…. What is a double blind study? Two orthopaedic surgeons reading an ECG
Double blind in orthopaedics?
EBM is not new……. “ ثم نرقى في البحث والمقاييس على التدريج والترتيب مع انتقاد المقدمات والتحفظ في النتائج ونجعل غرضنا في جميع ما نستقرئه ونتصفحه استعمال العدل لا اتباع الهوى ونتحرى في سائر ما نميزه وننتقده طلب الحق لا الميل مع الآراء” الحسن بن الهيثم
I will tell you  NOTHING   about back pain management
I will show you how YOU can  FIND   EVERYTHING   about back pain management
Objectives What is EBM? How to ask an answerable question? How to search for an answer? How to assess the quality of the evidence?
GCC EBHC
National & Gulf Center for EBHP
Statistically speaking… An hour presentation is  shorter than 5 days workshop (p<0.05)
What is EBM? Haynes et al.  BMJ  2002;324:1350 Clinical Circumstances Research Evidence Patients’ Preferences Clinical Expertise
5As of EBM
Is this a good question? What is the best treatment of acute back pain?
Asking a good question (PICO)! P opulation I ntervention C ontrol O utcome
Is this a good question? In adult patients younger than 50 years old with acute low back pain, does bedrest reduce the risk of recurrence of pain within one year compared with physiotherapy? P: Adult patients <50yr with acute LBP I: Bedrest C: Physiotherapy O: Recurrence of pain within one year
 
How would you search for answers? Ask the audience Ask a friend Flip through a textbook Google it up!
What’s wrong with textbooks? Excellent for the principles & basic knowledge Usually single authored chapters Likely biased, author’s opinion Not peer-reviewed Outdated (at least 4 years)
What’s wrong with googling?
What’s wrong with googling? Reliability & credibility of source Google Scholar is good
So what to do?
5S Hierarchy of Evidence Haynes RB. Evid Based Med 2006;11:162-164  RCTs, Cohort, Case control, Case series Expert Opinion: Classical Textbooks
Primary Sources Original articles Through databases: MEDLINE, EMBASE Using: PubMed, OVID You have to retrieve and appraise the articles Strength (pyramid) of evidence
Pyramid of Evidence http://library.downstate.edu/EBM2/2100.htm 
 
 
MeSH  (Medical Subject Headings)
 
It is a “strategy” Acute Low Back Pain OR &quot;Low Back Pain&quot;[Mesh] AND Low Back Ache Low Backache OR OR AND Treatment Management Therapy OR OR OR Surgery
PubMed Tutorials
 
 
 
 
Critical Appraisal
 
 
It’s time consuming
Secondary Sources Systematic Reviews
Syntheses The authors have done the work for you Hopefully : They asked a good question They searched the literature systematically (keywords & MeSH) They identified the studies and assessed their quality This is called  Systematic Review If they did statistical combination of results, this is called  Meta-analysis
How to search for “Syntheses”? Same databases: MEDLINE, EMBASE Cochrane Library
PubMed
 
Cochrane Library
 
 
 
Are all syntheses good? You still have to appraise the quality of these systematic reviews and meta-analyses It’s time consuming
Appraisal
 
So what’s next? Critically-Appraised  Journal Articles & Abstracts Evidence-Based  Guidelines & Textbooks
Synopses Physicians with training in research methodology: Read the articles Assess their quality Summarize them for you Many journals:  JBJS(A) Evidence-Based Orthopaedics Section ACP Journal Club Database of Abstracts of Reviews of Effects (DARE)
 
 
Summaries Evidence-based guidelines and textbooks Examples: UptoDate Clinical Evidence National Guideline Clearinghouse
http://clinicalevidence.bmj.com/
http://www.guideline.gov/
 
 
 
 
 
 
Systems This is the ultimate goal Computerized decision support Too sophisticated for us to think about now
All what we’ve talked about Research Evidence
To practice EBM, we need all the four Clinical Circumstances Research Evidence Patients’ Preferences Clinical Expertise
We need….. To apply the evidence as it applies to our local hospitals To involve the patients actively in the decision making To have our own studies: Different social, cultural, ethnic, and economical backgrounds
http://www.andrews-clinic-natural-therapies.co.uk/documents/54.html
Resources
http://eapps.ngha.med.sa/ebm/
http://ebmjeddah.info/
Information Overflow
MDLinx.com
http://plus.mcmaster.ca/EvidenceUpdates/
This presentation is available online www.uqu.edu.sa/ssbajammal المحاضرات
Summary EBM is not only research evidence 5As of EBM: Ask, Acquire, Appraise, Apply, Act Always ask a PICO question Search: Summaries    Synopses    Syntheses    Studies Keywords & MeSH headings Use Clinical Queries Appraise [email_address]

Evidence-based Back Pain Management (EBM in general)