Free radical injury
Dr.T.Arivazhagan
Department of Pathology
•Highly reactive chemical entities
•Has single unpaired electron in their outer orbit
•These are highly toxic under some conditions
•Generally unstable
1. Loss of one electron from a non radical
2. Gain of one electron from non radical
Types
1. oxygen centered free radical
- Superoxide, Hydroxyl ions
2. Sulfur centered free radical
- Thiyl radicals
3. Carbon centered free radical
4. Nitrogen centered free radical
Fenton reaction
Free radical injury
Free radical injury
Free radical injury
Free radical injury
Free radical injury

Free radical injury