© 2018 Change Healthcare LLC and/or its subsidiaries or affiliates. All Rights Reserved. PROPRIETARY & CONFIDENTIAL 1© 2018 Change Healthcare LLC and/or its subsidiaries or affiliates. All Rights Reserved. PROPRIETARY & CONFIDENTIAL
© 2018 Change Healthcare LLC and/or its subsidiaries or affiliates. All Rights Reserved. PROPRIETARY & CONFIDENTIAL 2© 2018 Change Healthcare LLC and/or its subsidiaries or affiliates. All Rights Reserved. PROPRIETARY & CONFIDENTIAL
HOW AI WILL REINVENT HEALTHCARE
Alex Ermolaev, Director of AI, Change Healthcare
PROPRIETARY & CONFIDENTIAL 3
The Change Healthcare Intelligent Healthcare Network…
• Extensive product/services, expertise, data,
and connectivity
• Tying our success to our customer: providers, payers
and consumers
• Independent, unbiased, & relentless drive
towards better healthcare
• Delivering practical innovation through
technology and partners
2,100
Payer Connections
1 in 5
US Patient
Records
$2 trillion
Healthcare Claims
Nearly 14 billion
Healthcare Transactions
5,500
Hospitals & Health Systems
800,000
Physicians117,000
Dentists
600
Laboratoriesh
Pervasive across healthcare
© 2018 Change Healthcare LLC and/or its subsidiaries or affiliates. All Rights Reserved. PROPRIETARY & CONFIDENTIAL 4
AI Team Evolution
Crawl
• Several data
scientists spread
across the company
• No leverage
• No visibility
Walk
• CEO/Board
commitment
• Pipeline of
projects
Walk Faster
• Rapid
experimentation
• AI engineering
• One-click training
and deployment
Run
© 2018 Change Healthcare LLC and/or its subsidiaries or affiliates. All Rights Reserved. PROPRIETARY & CONFIDENTIAL 5
Why Apply AI to Healthcare?
US Industry by Revenue
R&D Budget
Number of AI Opportunities
Number of AI Startups
#1
#2
#1
#1
Most Important for Saving Lives#1
© 2018 Change Healthcare LLC and/or its subsidiaries or affiliates. All Rights Reserved. PROPRIETARY & CONFIDENTIAL 6
AI in Healthcare
Summary
Early Diagnosis Health Monitoring Medical Imaging
Medical
Intelligence
Precision Medicine
Personalized
Treatment Plans
Clinical Trials
Personalization
Smart Electronic
Health records
Payment Accuracy Patient Identification
and Retention
Optimized
Healthcare
System
© 2018 Change Healthcare LLC and/or its subsidiaries or affiliates. All Rights Reserved. PROPRIETARY & CONFIDENTIAL 7
Medical Intelligence
Early Diagnosis and
Disease Prediction
Health Monitoring
Devices
Computer-Aided
Detection
PROPRIETARY & CONFIDENTIAL 8
Sepsis Diagnostics
1.6M diagnoses/year (US)
25%-30% Mortality Rate
#3 Cause of Death
#1 Hospital Cost in US
Antibiotics increase survival rate
7.6% per hour
© 2018 Change Healthcare LLC and/or its subsidiaries or affiliates. All Rights Reserved. PROPRIETARY & CONFIDENTIAL 9
Sepsis Diagnostics (Continued)
Source: https://www.researchgate.net/publication/326661039_Applying_Artificial_Intelligence_to_Identify_Physiomarkers_Predicting_Severe_Sepsis_in_the_PICU
PROPRIETARY & CONFIDENTIAL 10
Medical Devices
© 2018 Change Healthcare LLC and/or its subsidiaries or affiliates. All Rights Reserved. PROPRIETARY & CONFIDENTIAL 11PROPRIETARY & CONFIDENTIAL
Brain
Subarachnoid Hemorrhage
Subdural hemorrhage
Extradural hemorrhage
Intraventricular hemorrhage
Parenchymal hemorrhage
Hydrocephalus
Midline shift
Descending transtentorial herniation
Ascending transtentorial herniation
Workflow Intelligence.AI
Intelligent Workflow driven by AI
Abdomen
Perforation / Free air
Bowel obstruction
Spinal epidural hemorrhage
Vertebral fracture
Chest
Pneumothorax
Aortic dissection
PE
Spinal epidural hemorrhage
Vertebral fracture
Neck
Retropharyngeal abscess
Spinal epidural hemorrhage
Vertebral fracture
Vertebral artery dissection
© 2018 Change Healthcare LLC and/or its subsidiaries or affiliates. All Rights Reserved. PROPRIETARY & CONFIDENTIAL 12
Personalization
Precision
Medicine
Personalized
Treatment Plans
Clinical
Trials
© 2018 Change Healthcare LLC and/or its subsidiaries or affiliates. All Rights Reserved. PROPRIETARY & CONFIDENTIAL 13
Personalized Treatment Plans
Source: https://www.media.mit.edu/publications/reinforcement-learning-for-designing-novel-clinical-trials-for-treating-cancer-patients/
© 2018 Change Healthcare LLC and/or its subsidiaries or affiliates. All Rights Reserved. PROPRIETARY & CONFIDENTIAL 14
Clinical Trials
Oncology Trials
3.4%
of oncology clinical trials
are completed
Patients Enrolled
5%
of cancer patients are
enrolled in clinical trials
Sources: http://blogs.sciencemag.org/pipeline/archives/2018/02/02/a-new-look-at-clinical-success-rates
https://www.beckershospitalreview.com/quality/just-5-of-cancer-patients-participate-in-clinical-trials-5-things-to-know.html
"I don't think it's an unwillingness on the patients' part. I don't
even think it's an unwillingness on the physician's part. It’s really
a system error...” Scott Delacroix, MD, told PBS NewsHour.
© 2018 Change Healthcare LLC and/or its subsidiaries or affiliates. All Rights Reserved. PROPRIETARY & CONFIDENTIAL 15
Optimized Healthcare System
Smart Electronic
Health records
Transaction Accuracy
And Streamlining
Patient Identification
and Retention
© 2018 Change Healthcare LLC and/or its subsidiaries or affiliates. All Rights Reserved. PROPRIETARY & CONFIDENTIAL 16
About 1/3 of Healthcare Spending is Wasted
Sources: https://advocacy.consumerreports.org/research/engaging-consumers-on-health-care-cost-and-value-issues/
© 2018 Change Healthcare LLC and/or its subsidiaries or affiliates. All Rights Reserved.
Medical Text
Understanding
Header ✓
Footer ✓
David A. Smith, M.D. ✓
Legalese ✓
Likely diagnoses ✓
Member info ✓
© 2018 Change Healthcare LLC and/or its subsidiaries or affiliates. All Rights Reserved. PROPRIETARY & CONFIDENTIAL 18
Problem: Medical Claims
1. Source: https://www.businesswire.com/news/home/20170626005391/en/Change-Healthcare-Analysis-Estimated-262-Billion-Healthcare
2. Source: Change Healthcare Internal Statistics
US Medical Claims:
$3T per year1
Claims Denied:
$262B per
year (9%)1
Cost of Rework:
$118 per claim1
Total Loss:
> $100B2
PROPRIETARY & CONFIDENTIAL 19
Example: Dual Enrollment
1 - CMS Fast Facts, January 2018: https://www.cms.gov/Research-Statistics-Data-and-Systems/Statistics-Trends-and-Reports/CMS-Fast-Facts/index.html
2- Kaiser Family Foundation: https://www.kff.org/medicare/state-indicator/medicare-beneficiaries-by-fpl/?currentTimeframe=0&sortModel=%7B%22colId%22:%22Location%22,%22sort%22:%22asc%22%7D
3- CMS, https://www.cms.gov/Medicare-Medicaid-Coordination/Medicare-and-Medicaid-Coordination/Medicare-Medicaid-Coordination-Office/DataStatisticalResources/Data-and-Statistical-Resources.html
Today
58.8M
Medicare beneficiaries
Live at or below
34%
of the federal poverty level
And only
10.6M
are dual-enrolled
© 2018 Change Healthcare LLC and/or its subsidiaries or affiliates. All Rights Reserved. PROPRIETARY & CONFIDENTIAL 20
AI in Healthcare
Summary
Early Diagnosis Health Monitoring Medical Imaging
Medical
Intelligence
Precision Medicine
Personalized
Treatment Plans
Clinical Trials
Personalization
Smart Electronic
Health records
Payment Accuracy Patient Identification
and Retention
Optimized
Healthcare
System
© 2018 Change Healthcare LLC and/or its subsidiaries or affiliates. All Rights Reserved. PROPRIETARY & CONFIDENTIAL 21
Healthcare AI Startups
Source: CBInsights
PROPRIETARY & CONFIDENTIAL 22
Embrace
Variety
Respect
Data
Understand
Workflow
AI in Healthcare Challenges
PROPRIETARY & CONFIDENTIAL 23
“In order to understand trust in the relationship
between humans and automation, we have to
explore trust in two dimensions: trust in the
technology and trust in the innovating firm.”
Source: https://hbr.org/2017/04/to-get-consumers-to-trust-ai-show-them-its-benefits
© 2018 Change Healthcare LLC and/or its subsidiaries or affiliates. All Rights Reserved. PROPRIETARY & CONFIDENTIAL 24© 2018 Change Healthcare LLC and/or its subsidiaries or affiliates. All Rights Reserved. PROPRIETARY & CONFIDENTIAL
Thank You!

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Global AI seattle How AI will Reinvent Healthcare

  • 1. © 2018 Change Healthcare LLC and/or its subsidiaries or affiliates. All Rights Reserved. PROPRIETARY & CONFIDENTIAL 1© 2018 Change Healthcare LLC and/or its subsidiaries or affiliates. All Rights Reserved. PROPRIETARY & CONFIDENTIAL
  • 2. © 2018 Change Healthcare LLC and/or its subsidiaries or affiliates. All Rights Reserved. PROPRIETARY & CONFIDENTIAL 2© 2018 Change Healthcare LLC and/or its subsidiaries or affiliates. All Rights Reserved. PROPRIETARY & CONFIDENTIAL HOW AI WILL REINVENT HEALTHCARE Alex Ermolaev, Director of AI, Change Healthcare
  • 3. PROPRIETARY & CONFIDENTIAL 3 The Change Healthcare Intelligent Healthcare Network… • Extensive product/services, expertise, data, and connectivity • Tying our success to our customer: providers, payers and consumers • Independent, unbiased, & relentless drive towards better healthcare • Delivering practical innovation through technology and partners 2,100 Payer Connections 1 in 5 US Patient Records $2 trillion Healthcare Claims Nearly 14 billion Healthcare Transactions 5,500 Hospitals & Health Systems 800,000 Physicians117,000 Dentists 600 Laboratoriesh Pervasive across healthcare
  • 4. © 2018 Change Healthcare LLC and/or its subsidiaries or affiliates. All Rights Reserved. PROPRIETARY & CONFIDENTIAL 4 AI Team Evolution Crawl • Several data scientists spread across the company • No leverage • No visibility Walk • CEO/Board commitment • Pipeline of projects Walk Faster • Rapid experimentation • AI engineering • One-click training and deployment Run
  • 5. © 2018 Change Healthcare LLC and/or its subsidiaries or affiliates. All Rights Reserved. PROPRIETARY & CONFIDENTIAL 5 Why Apply AI to Healthcare? US Industry by Revenue R&D Budget Number of AI Opportunities Number of AI Startups #1 #2 #1 #1 Most Important for Saving Lives#1
  • 6. © 2018 Change Healthcare LLC and/or its subsidiaries or affiliates. All Rights Reserved. PROPRIETARY & CONFIDENTIAL 6 AI in Healthcare Summary Early Diagnosis Health Monitoring Medical Imaging Medical Intelligence Precision Medicine Personalized Treatment Plans Clinical Trials Personalization Smart Electronic Health records Payment Accuracy Patient Identification and Retention Optimized Healthcare System
  • 7. © 2018 Change Healthcare LLC and/or its subsidiaries or affiliates. All Rights Reserved. PROPRIETARY & CONFIDENTIAL 7 Medical Intelligence Early Diagnosis and Disease Prediction Health Monitoring Devices Computer-Aided Detection
  • 8. PROPRIETARY & CONFIDENTIAL 8 Sepsis Diagnostics 1.6M diagnoses/year (US) 25%-30% Mortality Rate #3 Cause of Death #1 Hospital Cost in US Antibiotics increase survival rate 7.6% per hour
  • 9. © 2018 Change Healthcare LLC and/or its subsidiaries or affiliates. All Rights Reserved. PROPRIETARY & CONFIDENTIAL 9 Sepsis Diagnostics (Continued) Source: https://www.researchgate.net/publication/326661039_Applying_Artificial_Intelligence_to_Identify_Physiomarkers_Predicting_Severe_Sepsis_in_the_PICU
  • 10. PROPRIETARY & CONFIDENTIAL 10 Medical Devices
  • 11. © 2018 Change Healthcare LLC and/or its subsidiaries or affiliates. All Rights Reserved. PROPRIETARY & CONFIDENTIAL 11PROPRIETARY & CONFIDENTIAL Brain Subarachnoid Hemorrhage Subdural hemorrhage Extradural hemorrhage Intraventricular hemorrhage Parenchymal hemorrhage Hydrocephalus Midline shift Descending transtentorial herniation Ascending transtentorial herniation Workflow Intelligence.AI Intelligent Workflow driven by AI Abdomen Perforation / Free air Bowel obstruction Spinal epidural hemorrhage Vertebral fracture Chest Pneumothorax Aortic dissection PE Spinal epidural hemorrhage Vertebral fracture Neck Retropharyngeal abscess Spinal epidural hemorrhage Vertebral fracture Vertebral artery dissection
  • 12. © 2018 Change Healthcare LLC and/or its subsidiaries or affiliates. All Rights Reserved. PROPRIETARY & CONFIDENTIAL 12 Personalization Precision Medicine Personalized Treatment Plans Clinical Trials
  • 13. © 2018 Change Healthcare LLC and/or its subsidiaries or affiliates. All Rights Reserved. PROPRIETARY & CONFIDENTIAL 13 Personalized Treatment Plans Source: https://www.media.mit.edu/publications/reinforcement-learning-for-designing-novel-clinical-trials-for-treating-cancer-patients/
  • 14. © 2018 Change Healthcare LLC and/or its subsidiaries or affiliates. All Rights Reserved. PROPRIETARY & CONFIDENTIAL 14 Clinical Trials Oncology Trials 3.4% of oncology clinical trials are completed Patients Enrolled 5% of cancer patients are enrolled in clinical trials Sources: http://blogs.sciencemag.org/pipeline/archives/2018/02/02/a-new-look-at-clinical-success-rates https://www.beckershospitalreview.com/quality/just-5-of-cancer-patients-participate-in-clinical-trials-5-things-to-know.html "I don't think it's an unwillingness on the patients' part. I don't even think it's an unwillingness on the physician's part. It’s really a system error...” Scott Delacroix, MD, told PBS NewsHour.
  • 15. © 2018 Change Healthcare LLC and/or its subsidiaries or affiliates. All Rights Reserved. PROPRIETARY & CONFIDENTIAL 15 Optimized Healthcare System Smart Electronic Health records Transaction Accuracy And Streamlining Patient Identification and Retention
  • 16. © 2018 Change Healthcare LLC and/or its subsidiaries or affiliates. All Rights Reserved. PROPRIETARY & CONFIDENTIAL 16 About 1/3 of Healthcare Spending is Wasted Sources: https://advocacy.consumerreports.org/research/engaging-consumers-on-health-care-cost-and-value-issues/
  • 17. © 2018 Change Healthcare LLC and/or its subsidiaries or affiliates. All Rights Reserved. Medical Text Understanding Header ✓ Footer ✓ David A. Smith, M.D. ✓ Legalese ✓ Likely diagnoses ✓ Member info ✓
  • 18. © 2018 Change Healthcare LLC and/or its subsidiaries or affiliates. All Rights Reserved. PROPRIETARY & CONFIDENTIAL 18 Problem: Medical Claims 1. Source: https://www.businesswire.com/news/home/20170626005391/en/Change-Healthcare-Analysis-Estimated-262-Billion-Healthcare 2. Source: Change Healthcare Internal Statistics US Medical Claims: $3T per year1 Claims Denied: $262B per year (9%)1 Cost of Rework: $118 per claim1 Total Loss: > $100B2
  • 19. PROPRIETARY & CONFIDENTIAL 19 Example: Dual Enrollment 1 - CMS Fast Facts, January 2018: https://www.cms.gov/Research-Statistics-Data-and-Systems/Statistics-Trends-and-Reports/CMS-Fast-Facts/index.html 2- Kaiser Family Foundation: https://www.kff.org/medicare/state-indicator/medicare-beneficiaries-by-fpl/?currentTimeframe=0&sortModel=%7B%22colId%22:%22Location%22,%22sort%22:%22asc%22%7D 3- CMS, https://www.cms.gov/Medicare-Medicaid-Coordination/Medicare-and-Medicaid-Coordination/Medicare-Medicaid-Coordination-Office/DataStatisticalResources/Data-and-Statistical-Resources.html Today 58.8M Medicare beneficiaries Live at or below 34% of the federal poverty level And only 10.6M are dual-enrolled
  • 20. © 2018 Change Healthcare LLC and/or its subsidiaries or affiliates. All Rights Reserved. PROPRIETARY & CONFIDENTIAL 20 AI in Healthcare Summary Early Diagnosis Health Monitoring Medical Imaging Medical Intelligence Precision Medicine Personalized Treatment Plans Clinical Trials Personalization Smart Electronic Health records Payment Accuracy Patient Identification and Retention Optimized Healthcare System
  • 21. © 2018 Change Healthcare LLC and/or its subsidiaries or affiliates. All Rights Reserved. PROPRIETARY & CONFIDENTIAL 21 Healthcare AI Startups Source: CBInsights
  • 22. PROPRIETARY & CONFIDENTIAL 22 Embrace Variety Respect Data Understand Workflow AI in Healthcare Challenges
  • 23. PROPRIETARY & CONFIDENTIAL 23 “In order to understand trust in the relationship between humans and automation, we have to explore trust in two dimensions: trust in the technology and trust in the innovating firm.” Source: https://hbr.org/2017/04/to-get-consumers-to-trust-ai-show-them-its-benefits
  • 24. © 2018 Change Healthcare LLC and/or its subsidiaries or affiliates. All Rights Reserved. PROPRIETARY & CONFIDENTIAL 24© 2018 Change Healthcare LLC and/or its subsidiaries or affiliates. All Rights Reserved. PROPRIETARY & CONFIDENTIAL Thank You!