This document outlines how to build a successful experimentation program. It discusses setting clear business metrics and prioritizing user problems through qualitative research. Key steps include forming hypotheses tied to user problems, prioritizing hypotheses using frameworks like ICE (Impact, Confidence, Ease), designing and testing experiments, and analyzing results to determine if the experiment solved problems and moved metrics. The success of an experimentation program depends on strong hypotheses, prioritization frameworks, and the speed of experimentation.