Hand hygiene is cleaning hands to reduce harmful microorganisms and prevent infection transmission. It is important because healthcare workers can spread infections on their hands. Proper hand hygiene includes washing hands with soap and water or using an alcohol-based hand rub, especially before and after contact with patients. Healthcare workers should clean their hands in various situations to prevent the spread of infections like multidrug-resistant organisms. Patients should also practice hand hygiene before eating and after using the bathroom.