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Healthcare in the Era of
Digital Disruption
Nawanan Theera-Ampornpunt, M.D., Ph.D.
January 29, 2020
www.SlideShare.net/Nawanan
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2003 M.D. (First-Class Honors)
2011 Ph.D. (Health Informatics), Univ. of Minnesota
Deputy Dean for Operations
Lecturer, Department of Clinical Epidemiology & Biostatistics
Faculty of Medicine Ramathibodi Hospital
Mahidol University
Interests: Health IT for Quality of Care, Social Media
IT Management, Security & Privacy
nawanan.the@mahidol.ac.th
SlideShare.net/Nawanan
นวนรรน ธีระอัมพรพันธุ์ (Nawanan Theera-Ampornpunt)
Line ID: NawananT
Introduction
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What words come to mind when you hear...
Digital Health
Transformation
4https://medium.com/@marwantarek/it-is-the-perfect-storm-ai-cloud-bots-iot-etc-4b7cbb0481bc
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http://www.ibtimes.com/google-deepminds-alphago-program-defeats-human-go-champion-first-time-ever-2283700
http://deepmind.com/ http://socialmediab2b.com
An Era of Smart Machines
6englishmoviez.com
Rise of the Machines?
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Digitizing Healthcare?
http://www.bloomberg.com/bw/stories/2005-03-27/cover-image-the-digital-hospital
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“Big data is like teenage sex:
everyone talks about it,
nobody really knows how to do it,
everyone thinks everyone else is doing it,
so everyone claims they are doing it...”
-- Dan Ariely @danariely (2013)
Substitute “Big data” with “AI”, “Blockchain”, “IoT”
of your choice.
-- Nawanan Theera-Ampornpunt (2018)
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Hype vs. Hope
Jeremy Kemp via http://en.wikipedia.org/wiki/Hype_cycle
http://www.gartner.com/technology/research/methodologies/hype-cycle.jsp
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Gartner Hype Cycle 2017
https://www.gartner.com/smarterwithgartner/top-trends-in-the-gartner-hype-cycle-for-emerging-technologies-2017/
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“Smart” Machines?
https://www.bbc.com/news/business-47514289
https://www.standardmedia
.co.ke/article/2001318679/e
thiopian-airlines-crash-
investigators-reach-
conclusion
12
A Real-Life Personal Story of
My Failure (as a Doctor and as
a Son) in Misdiagnosing
My Mom
Would AI Help?
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• Nothing is certain in medicine &
health care
• Large variations exist in patient
presentations, clinical course,
underlying genetic codes, patient &
provider behaviors, biological
responses & social contexts
Why Clinical Judgment Is Still Necessary?
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• Most diseases are not diagnosed by
diagnostic criteria, but by patterns of
clinical presentation and perceived
likelihood of different diseases given
available information (differential
diagnoses)
• Human is good at pattern
recognition, while machine is good at
logic & computations
Why Clinical Judgment Is Still Necessary?
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• Machines are (at best) as good as
the input data
–Not everything can be digitized or
digitally acquired
–Not everything digitized is accurate
(“Garbage In, Garbage Out”)
• Experience, context & human touch
matters
Why Clinical Judgment Is Still Necessary?
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Digitization 
Digital Transformation
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Let’s take a look at
these pictures...
18Image Source: https://en.wikipedia.org/wiki/Industrial_robot (KUKA Roboter GmbH)
“Smart” Manufacturing
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Image Sources: http://isarapost.net/home/?p=17760
http://www.telecomjournalthailand.com/ตอบโจทย์โมเดลทางธุรกิจ/
“Smart” Banking
20ER - Image Source: nj.com
Healthcare (On TV)
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(At an undisclosed hospital)
Healthcare (Reality)
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• Life-or-Death
• Difficult to automate human decisions
– Nature of business
– Many & varied stakeholders
– Evolving standards of care
• Fragmented, poorly-coordinated systems
• Large, ever-growing & changing body of
knowledge
• High volume, low resources, little time
Why Healthcare Isn’t (Yet) “Smart”?
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But...Are We That Different?
Input Process Output
Transfer
Banking
Value-Add
- Security
- Convenience
- Customer Service
Location A Location B
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Input Process Output
Assembling
Manufacturing
Raw Materials Finished
Goods
Value-Add
- Innovation
- Design
- QC
But...Are We That Different?
25
But...Are We That Different?
Input Process Output
Patient Care
Health care
Sick Patient Well Patient
Value-Add
- Technology & medications
- Clinical knowledge & skills
- Quality of care; process improvement
- Information
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• Large variations & contextual dependence
Why Health care Isn’t Like Any Others?
Input Process Output
Patient
Presentation
Decision-
Making
Biological
Responses
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“To computerize
the hospital”
“To go paperless”
“To become a
Digital Hospital”
“To Have
EHRs”
Why Adopting Health IT?
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• “Don’t implement technology just for
technology’s sake.”
• “Don’t make use of excellent technology.
Make excellent use of technology.”
(Tangwongsan, Supachai. Personal communication, 2005.)
• “Health care IT is not a panacea for all that ails
medicine.” (Hersh, 2004)
Some “Smart” Quotes
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Being Smart #1:
Stop Your
“Drooling Reflex”!!
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Being Smart #2:
Focus on Information &
Process Improvement,
Not Technology
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If not “Digital Hospital”
or “Paperless Hospital”
Then What Should We
Aspire to Be?
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“Smart Hospital”
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So How is
a “Smart Hospital”
Different from a Digital or
Paperless Hospital?
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Smart Healthcare For Policymakers?
Image Source: http://healthdata.moph.go.th/kpi/2557/ProvinceKpiTopicListAll.php?provincecode=99
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Smart Healthcare For Health Promoters?
Image Source: http://www.hiso.or.th/hiso/picture/reportHealth/ThaiHealth2014/thai2014_3.pdf
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Smart Healthcare For Clinicians?
Image Source: http://www.medscape.com/viewarticle/780298
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Smart Healthcare For Patients & Consumers?
Image Source: Agence France-Presse/Getty Images
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So What Exactly Is Smart Healthcare?
Image Source: http://cdn2.hubspot.net/hub/134568/file-1208368053-jpg/6-blind-men-hans.jpg
39https://www.youtube.com/watch?v=gxz9ZVvduGc
Connecting People to a Healthy Future
With Personalized Care – Kaiser Permanente
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Back to
something simple...
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To treat & to care
for their patients
to their best
abilities, given
limited time &
resources
Image Source: http://en.wikipedia.org/wiki/File:Newborn_Examination_1967.jpg (Nevit Dilmen)
What Clinicians Want?
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Why Aren’t We Talk About These Words?
http://hcca-act.blogspot.com/2011/07/reflections-on-patient-centred-care.html
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The Goal of Health Care
The answer is already obvious...
“Health”
“Care”
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• Safe
• Timely
• Effective
• Patient-Centered
• Efficient
• Equitable
Institute of Medicine, Committee on Quality of Health Care in America. Crossing the quality
chasm: a new health system for the 21st century. Washington, DC: National Academy
Press; 2001. 337 p.
High Quality Care
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Information Is Everywhere in Healthcare
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WHO (2009)
Components of Health Systems
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WHO (2009)
WHO Health System Framework
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(IOM, 2001)(IOM, 2000) (IOM, 2011)
Landmark Institute of Medicine Reports
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• Humans are not perfect and are bound to
make errors
• Highlight problems in U.S. health care
system that systematically contributes to
medical errors and poor quality
• Recommends reform
• Health IT plays a role in improving patient
safety
Summary of These Reports
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Image Source: (Left) http://docwhisperer.wordpress.com/2007/05/31/sleepy-heads/
(Right) http://graphics8.nytimes.com/images/2008/12/05/health/chen_600.jpg
To Err is Human 1: Attention
51Image Source: Suthan Srisangkaew, Department of Pathology, Facutly of Medicine Ramathibodi Hospital
To Err is Human 2: Memory
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• Cognitive Errors - Example: Decoy Pricing
The Economist Purchase Options
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• Print & web subscription $125
Ariely (2008)
16
0
84
The Economist Purchase Options
• Economist.com subscription $59
• Print subscription $125
• Print & web subscription $125
68
32
# of
People
# of
People
To Err is Human 3: Cognition
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• It already happens....
(Mamede et al., 2010; Croskerry, 2003; Klein,
2005)
• What if health IT can help?
What If This Happens in Healthcare?
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• Medication Errors
–Drug Allergies
–Drug Interactions
• Ineffective or inappropriate treatment
• Redundant orders
• Failure to follow clinical practice guidelines
Common Errors
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Being Smart #3:
“To Err is Human”
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External Memory
Knowledge Data
Long Term Memory
Knowledge Data
Inference
DECISION
PATIENT
Perception
Attention
Working
Memory
CLINICIAN
Elson, Faughnan & Connelly (1997)
Clinical Decision Making
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Example of “Alerts & Reminders”
Reducing Errors through Alerts & Reminders
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Being Smart #4:
Link IT Values to
Quality (Including Safety)
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Health IT
Health
Information
Technology
Goal
Value-Add
Means
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ภาพรวมของงานด้าน Health IT
Intra-Hospital IT
• Electronic Health Records &
Health IT for Quality & Safety
• Digital Transformation
• AI, Data Analytics
• Hospital IT Quality
Improvement (HA-IT)
Inter-Hospital IT
• Health Information
Exchange (HIE)
Extra-Hospital IT
• Patients: Personal
Health Records (PHRs)
• Public Health: Disease
Surveillance & Analytics
Patient
at Home
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Strategic
Operational
ClinicalAdministrative
LIS
Health Information ExchangeBusiness
Intelligence
Word
Processor
Social
Media
PACS
Personal Health Records
Clinical Decision Support Systems
Computerized Physician Order Entry
Electronic Health Records
Admission-Discharge-Transfer
Master Patient Index
Enterprise Resource Planning
Vendor-Managed Inventory
Customer Relationship Management
4 Quadrants of Hospital IT
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ภาพรวมของงานด้าน Health IT
Intra-Hospital IT
• Electronic Health Records &
Health IT for Quality & Safety
• Digital Transformation
• AI, Data Analytics
• Hospital IT Quality
Improvement (HA-IT)
Inter-Hospital IT
• Health Information
Exchange (HIE)
Extra-Hospital IT
• Patients: Personal
Health Records (PHRs)
• Public Health: Disease
Surveillance & Analytics
Patient
at Home
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YouTube: TEDxMahidolU Nawanan
https://www.youtube.com/watch?v=MuoDaJAqQ6c
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Hospital A Hospital B
Clinic D
Policymakers
Patient at
Home
Hospital C
HIE Platform
Health Information Exchange (HIE)
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Areas of Health Informatics
Patients &
Consumers
Providers &
Patients
Healthcare
Managers, Policy-
Makers, Payers,
Epidemiologists,
Researchers
Copyright  Nawanan Theera-Ampornpunt (2018)
Clinical
Informatics
Public
Health
Informatics
Consumer
Health
Informatics
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Incarnations of Health IT
Clinical
Informatics
Public
Health
Informatics
Consumer
Health
Informatics
HIS/CIS
EHRs
Computerized Physician
Order Entry (CPOE)
Clinical Decision
Support Systems
(CDS) (including AI)
Closed Loop
Medication
PACS/RIS
LIS
Nursing
Apps
Disease Surveillance
(Active/Passive)
Business
Intelligence &
Dashboards
Telemedicine
Real-time Syndromic
Surveillance
mHealth for Public
Health Workers &
Volunteers
PHRs
Health Information
Exchange (HIE)
eReferral
mHealth for
Consumers
Wearable
Devices
Social
Media
Copyright  Nawanan Theera-Ampornpunt (2018)
67
Where We Are Today...
Copyright  Nawanan Theera-Ampornpunt (2018)
Clinical
Informatics
Public
Health
Informatics
Consumer
Health
Informatics
Technology that
focuses on the sick,
not the healthy
Silos of data
within hospitalPoor/unstructured
data quality
Lack of health data
outside hospital
Poor data
integration across
hospitals/clinics
Poor data integration
for monitoring &
evaluation
Poor data quality (GIGO)
Finance leads
clinical outcomes
Poor IT change
management
Cybersecurity
& privacy risks
Few real examples
of precision
medicine
Little access
to own
health data
Poor patient
engagement
Poor accuracy
of wearables Lack of evidence
for health values
Health literacy
Information 
Behavioral
change
Few standards
Lack of health IT
governance
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Healthtech Startup Ecosystem
www.facebook.com/HealthTechThailand/ No endorsements implied
69WHO & ITU
Achieving Health Information Exchange (HIE)
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https://www.hfocus.org/content/2016/02/11783
https://www.hfocus.org/content/2016/03/11968
https://www.hfocus.org/content/2016/09/12671
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Myths
• We don’t need standards
• Standards are IT people’s jobs
• We should exclude vendors from this
• We need the same software to share data
• We need to always adopt international
standards
• We need to always use local standards
Theera-Ampornpunt (2011)
Myths & Truths about Standards
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Being Smart #5:
Go for Systems that Use
Standards, Not a Unified,
Conquer-the-World System
Image Source: https://www.businessinsider.in/google-let-users-play-with-thanos-destructive-
power/articleshow/69054170.cms
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• CDS as a replacement or supplement of
clinicians?
– The demise of the “Greek Oracle” model (Miller & Masarie, 1990)
The “Greek Oracle” Model
The “Fundamental Theorem” Model
Friedman (2009)
Wrong Assumption
Correct Assumption
Clinical Decision Support Systems (CDS)
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Being Smart #6:
Don’t Replace
Human Users.
Use ICT to Help Them
Perform Smarter & Better.
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Envisioning a Smart Health Thailand

Healthcare in the Era of Digital Disruption (January 29, 2020)