Uploaded bySubham Kumar Vishwakarma
Hematinics
This document discusses hematinics, which are nutrients that help form blood cells. It defines hematinics as iron, vitamin B12, and folate, and notes deficiencies can cause anemia. Various oral and parenteral hematinic preparations are listed, along with side effects like constipation. Interactions between hematinics and other drugs are described, such as penicillamine decreasing iron absorption. Hematopoietic growth factors that stimulate red blood cell production, like erythropoietin, are also mentioned.
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Hematinics
- 1. SHUBHAM KUMAR VISHWAKARMA 5thsem B.Pharm
- 26. Haematuria-- presence ofblood in urine
- 34. A hematinic isa nutrient required for the formation of blood cells in the process of hematopoiesis. The main hematinics are iron, B12, and folate. Deficiency in hematinics can lead to anaemia. In cases of hematinic deficiency, hematinics can be administered as medicines, in order to increase the hemoglobin content of the blood. Erythropoietin (EPO) is a hormone that stimulates erythropoiesis
- 35. How the interactionoccurs Your medicine contains aluminum, calcium, iron, lanthanum, magnesium, and/or zinc, which are cations that may bind to your antibiotic in your digestive tract. This prevents your body from absorbing the antibiotic. What might happen: The blood levels of your antibiotic may be decreased, which will decrease the effectiveness in treating your infection. Allergi Liver disfunction
- 36. • Amoxicilline &clavulenic acid 3 g ( beeta lactmase inhibitor) antibiotic • Use in bacterial infection • Eg UIT, wound healing
- 38. • Mean corpuscular volume(MCV) laboratory test • completeblood count (CBC) • mean corpuscular hemoglobin concentration (MCHC) test
- 39. • Stomach &intestinal problem eg ulcer, colitis • Tetracycline antibiotics • Thyroid medication (levo thyroxine) • Antibiotics – ciprofloxacine , quinolones , levofloxacine • Iron Metabolism Disorder causing Increased Iron Storage • Ulcerated Colon
- 40. Iron salts areoften available in combinations with "absorption stimulating" additives (e.g. ascorbic acid) and as gastric juice-resistant and slow-release preparations. These special preparations probably do not offer any relevant advantage compared to mono- preparations.
- 41. • Penicillamine interactswith IRON Penicillamine is used for Wilson's disease and rheumatoid arthritis. Iron might decrease how much penicillamine your body absorbs and decrease the effectiveness of penicillamine. To avoid this interaction take iron two hours before or two hours after taking penicillamine.
- 42. Side Effects Constipation, diarrhea,stomach cramps, or upset stomach may occur. These effects are usually temporary and may disappear as your body adjusts to this medication Iron may cause your stools to turn black, an effect that is not harmful.
- 70. Hematinics classification Oral preparations Ferrousgluconate Ferrous sulphate Ferrous fumarate Colloidal ferric hydroxide Carbonyl iron sulphate Ferrous succinate Ferrous glycine Ferric glycerophosphate Ferrous ammonium citrate Ferrous aminoate Ferric hydroxide polymaltose
- 71. Parenteral Iron dextran lron sorbitolcitrate complex Iron sucrose Iron dextrin (polymaltose) Vitamin B12 Cyanocobalamin Methylcobalamin Hydroxycobalamin
- 72. • Hematopoietic GrowthFactors • Erythropoietin • Darbepoietin
- 77.