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HOCM
This document provides an overview of hypertrophic cardiomyopathy (HCM). It defines HCM as an increased left ventricular wall thickness of 15 mm or more that is not due to abnormal loading conditions. HCM is caused by mutations in sarcomere genes. Symptoms can include left ventricular outflow tract obstruction and complications such as heart failure, atrial fibrillation, and sudden cardiac death. The document discusses the diagnosis of HCM using echocardiography, cardiac MRI and other imaging tools. It also reviews treatments such as medications, surgical myectomy to relieve outflow tract obstruction, alcohol septal ablation, implantable cardioverter-defibrillators and heart transplantation.
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HOCM
- 1. HOCM MOHAMED A. GABR CARDIOTHORACICSURGERY SPECIALIST AT MUH MANSOURA UNIVERSITY 2019
- 2. DEFINITON HCM is definedby the ↑↑ LV wall thickness ≥15 mm in one or more LV myocardial segments. measured by any imaging technique that is not solely explained by abnormal loading conditions. HCM is genetically determined heart muscle disease caused by mutations in one of several sarcomere genes which encode components of the contractile apparatus.
- 3. LVOTO peak Doppler LVOT pressure gradient≥ 30 mm Hg Gradient ≥50 mm Hg : haemodyn. sig. LVOTO.
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- 31. COMPLICATIONS Death: Sudden andnon-sudden Atrial dilatation: AF Mitral valve disease: MR Myocardial infarction Pulmonary hypertension Heart block and BBB
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- 49. Combined TASM +Apical
- 52. COMPLICATIONS OF SM Conductiondisturbances: Complete heart block or RBBB Perioperative Myocardial Infarction Iatrogenic VSD Postoperative Pressure Gradients Residual Mitral Regurgitation Death
- 53. 3- INTERVENTIONAL ASA ICDMITRACLIP
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- 61. Makavos, G., Κairis,C., Tselegkidi, M. E., Karamitsos, T., Rigopoulos, A. G., Noutsias, M., & Ikonomidis, I. (2019). Hypertrophic cardiomyopathy: an updated review on diagnosis, prognosis, and treatment. Heart failure reviews, 1-21. Wan, B., Rahnavardi, M., Tian, D. H., Phan, K., Munkholm-Larsen, S., Bannon, P. G., & Yan, T. D. (2013). A meta-analysis of MitraClip system versus surgery for treatment of severe mitral regurgitation. Annals of cardiothoracic surgery, 2(6), 683. Mohr, F. W., Seeburger, J., & Misfeld, M. (2013). Keynote Lecture—Transmitral hypertrophic obstructive cardiomyopathy (HOCM) repair. Annals of cardiothoracic surgery, 2(6), 729. Yacoub, M. H., Afifi, A., Saad, H., Aguib, H., & ElGuindy, A. (2017). Current state of the art and future of myectomy. Annals of cardiothoracic surgery, 6(4), 307. Messmer, B. J. (2004). Extended myectomy for hypertrophic obstructive cardiomyopathy. Operative Techniques in Thoracic and Cardiovascular Surgery, 9(4), 268-277. Khouzam, R. N., & Naidu, S. S. (2014). Current status and future perspectives on alcohol septal ablation for hypertrophic obstructive cardiomyopathy. Current cardiology reports, 16(5), 478. Naidu, S. S. (Ed.). (2019). Hypertrophic Cardiomyopathy. Nguyen, A., & Schaff, H. V. (2017). Transaortic septal myectomy for obstructive hypertrophic cardiomyopathy. Operative Techniques in Thoracic and Cardiovascular Surgery, 22(4), 200-215. References
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