How to read ICD episode?
ICD Follow Up Standard
• ICD/CRT-D: 3-6 Months Suggested
• Battery Voltage (and Impedance)
• Capacitor Charge Time
• Pacing and sensing threshold(s) for atrium, right and left ventricle (all leads)
• Pacing lead impedance(s) for all leads
• Shocking Impedances for defibrillation leads
• Arrhythmias detected by device
• % of pacing/sensing in each chamber
• Therapies required for termination of SVT/VT/VF
• Review of main programmed parameters
• Review of any device triggered alerts
• Review of hemodynamic measurements when available
* Wilkoff BL, Auricchio A, et al - HRS/EHRA Expert Consensus on the Monitoring of Cardiovascular Implantable Electronic Devices
(CIED): Description of Techniques, Indications, Personnel, Frequency and Ethical Considerations - May 14, 2008
Episodes Review
• Start with the VF episodes/Therapy Delivred Episodes
• Consider the device warnings
• For each episode check:
• if it is a “true” (clinical) VT/VF
• the detection
• the therapy
• Special Functions
• Other factors can influence your judgement
• Preceding symptoms
• Palpitations (irregular -> AF, regular -> SVT,
VT)
• Changes in medications
• Recent reprogramming
• Other diseases (co-morbidities)
Evaluate ICD shock
Almost everything at first Sight ...
1. Present Rhythm and
Rate
5. Episodes
4. Device
observations /
Warnings
3. Lead(s) Status
2. Battery and Capacitors
Stored Episode Review
Read episodes and analyze
•Related Patient symptoms
•Did discriminators give correct diagnosis?
•Appropriate or Inappropriate therapies?
•Single Episode or Multiple
Read episodes and analyze
•Check for Episode Initiation
•Check for terminations
Review ICD Shock Episode
Inappropriate Shock
Tachycardia
Absent
(Over sensing)
Intracardiac
T/P wave
Double count
Extracardiac
EMI
Myopotentials
Present
(Inappropriate SVT
detection)
The ICD EGM Signal
• Nearfield
• Electrodes are close in range
• EGM Source = Tip-to-Ring / Tip-to-Coil
• Narrow signal – less myocardium in range
• Used for arrhythmia detection
Farfield
Electrodes are further in range
EGM Source = Variable
More myocardium covered in range
Can resemble surface EKG
SINUS RHYTHM VT
ICD always uses a Near Field EGM source for sensing and
detection to avoid oversensing
ICD EGM Options
Extracardiac oversensing
Myopotentials
•Myopotentials are high-frequency, low-amplitude electrical transients generated
by skeletal muscles, including inter-costal muscles or the diaphragm.
Electrograms from a stored episode showing noise on the electrogram recorded between the SVC coil and pulse generator, and the absence of noise on the
V sense/pace signal (right ventricular tip to right ventricular ring).
Skeletal muscle oversensing
Different sensing configurations during isometric left arm exercise showing noise seen only when
the pulse generator was part of the recording suggesting that the signals are originating from in or
near the pocket.
•Provocative skeletal isometric exercise involving the upper extremities and abdominal muscles
•Absence of noise when can is removed from the sensing circuit
Diaphragmatic myo- potentials
diaphragmatic myopotentials presents as low-amplitude, high frequency signals
most of the time detected exclusively in the near-field channel with no alteration
in the shock electrogram.
(Top) Diaphragmatic myopotential oversensing during Valsalva manoeuvre with sensitivity
programmed in nominal: stored right ventricular and shock electrograms. (Bottom)
Abolishment of oversensing during Valsalva manoeuvre with sensitivity programmed in least:
stored right ventricular and shock electrograms.
NSVT EGM Recorded by Device due to oversensing :
(Early Lead Warning )
P wave oversensing- Due to lead Dislodgement
in Acute Phase Oversensing in Near Field EGM
ICD Ventricular Oversensing: Intracardiac Oversensing
TWOS: T wave Oversensing
Enhanced Filter and Special Sensing Parameters to Avoid
TWOS
DYNAMIC SENSITIVITY ADJUSTMENT
Features to minimize T-wave oversensing
Lead failure
Lead Problems :Lead failure
• It occurs during a small fraction (,8%) of the cardiac cycle
•The pacing-lead impedance may be abnormal and intermittent.
•signals are intermittent and have a Low frequency.
•Usually, at least some signals are not cyclic.
• Often, some intervals are nonphysiological, shorter than typical physiological
intervals.
• It often saturates the amplifier that often Signal amplitude may exceed the
range of the sensing amplifier and thus appear truncated.
Lead Noise vs True VT/VF Episodes
Proprietary and confidential — do not distribute
Clinical
presentation
Noise VF
RV Near Field channel
Discrimination
channel (RV coil –
can):
Rate Correlation NO YES
Technical complication Oversensing None
Decision of
SecureSense™
Inhibit therapy Deliver therapy
• Detects and differentiates
lead noise from a real VT/VF
thanks to a rate comparison
between the near field
channel and a new reference
channel (called
discrimination channel)
• Discrimination of lead noise
in VT zone as well as in VF
zone
• Also able to detect non-
sustained RV noises
Lead Noise Discriminator : Functional principles
• lead noise often generated by the following
complications :
Pace/Sense lead fracture
Insulator rupture
Loose set screw
Lead not seated properly in connector
How to read ICD episode_Dr Kush Bhagat.pptx
Tachycardia present
• VF? – Analyse EGM to verify
• VT? – Analyse EGM to differentiate SVT/VT
Shock
Tachycardia
Duration/
no. intervals
Ignore
non-
sustained
Detection
Enhance-ments
Discrimin-ation
Ignore
SVT
• Morphology onset,
stability, other logic
• Single/dual chamber
ATP
• Terminate VT
• Allow time  self-
term
• Terminate some
SVT
VT
Ignore slow
rhythms (VT,
SVT)
Heart rate
threshold
Characteristics real VT vs SVT
A-Fib/Flutter
Sinus Tach Other 1:1 SVT
200 bpm
200 bpm 200 bpm 200 bpm
VT
Fast V-V Cycle Length Due To…
Onset
Stability
EGM
Morphology
Sudden
Regular
Wide /
Different QRS
Gradual Sudden Sudden
Narrow/
Normal QRS
Narrow/
Normal QRS
Narrow/
Normal QRS
Irregular Regular
Regular
EGM to differentiate SVT/VT
• Single chamber ICD
– Unstable rhythm is more likely to
represent AF,
– Gradual acceleration is more compatible
with sinus tachycardia
– Sudden onset regular tachycardias – SVT
(AVNRT, AT, Afl) or VT
• Compare morphology of far-field channel
from sinus rhythm with the one in
arrhythmia
• Morphology of beats that immediately
follow shocks should not be relied on for
comparison because of possible EGM
distortion
ATP
EGM to differentiate SVT/VT
• ATP response
• In V=A Tachycardia, During ATP
– If AV dissociation – AT > AVNRT >> VT
– If retrograde AV blocks – AVNRT > VT
– Arrhythmia termination by ATP – supports VT >> AVRT, AVNRT
– If atrial acceleration to ATP (entrainment), then after ATP stops
• VAAV – AT
• VVA – VT
• VAV – Not helpful
EGM to differentiate SVT/VT
• Dual chamber ICD
– Atrial sensing
• V>A vs. V<A
• PVC vs. PAC initiated
• If V=A, Driving chamber
– A-A followed by V-V vs. V-V
followed by A-A
Chamber Onset
ATP
How to read ICD episode_Dr Kush Bhagat.pptx
Appropriate Shock
• Single shock
• Multiple shocks
– Ineffective Initial shocks – High DFT
– Incessant VT
– VT Storm
– Appropriate shocks for AF – If AF defibrillation ‘ON’
Multiple shocks / VT storm
Multiple shocks / VT storm
“VT Storm / Electrical Storm”
• Clustering episodes of VT/VF
in a short amount of time
• “Electrical Storm” defined as > 3
VT episodes treated by ICD
within a 24 hour period
• 10 – 20% of ICD patients
Electrical Storm:
≥3 VA/24 Hours
Reversible
Causes
AAD
Catheter
Ablation
Neural
Modulation
Palliation/
Replacement
Therapies
•K blocker
•Na blocker
•β blocker
•Triggers
•Substrate
modification
• Cooling
• Anesthesia
• Stellate blocks
• Denervation
surgery
•Team
approach
•Electrolytes
•Ischemia
•Inflammation
•Triggers
VT storm
• Treat ischemia or other precipitating factors such as HF
• Judicious use of a magnet or inactivation of ICD therapy
• Pharmacological therapy for VT (e.g. β-blockers, amiodarone); possible catheter
ablation
• IABP or hemodynamic support for hypotension
• Replace electrolytes (K+, Mg2+)
• Left stellate ganglionic blockade in selected patients
• Identify specific diseases that may need specific therapy (e.g. recurrent VT in
Brugada syndrome - isoproterenol and quinidine)
SYNCOPE WITH NO APPARENT SHOCK
How to read ICD episode_Dr Kush Bhagat.pptx
CASE EXALMPLES
Background
• 67-year-old man implanted with a single-chamber ICD for the management of
advanced ischemic cardiomyopathy complicated by repetitive episodes of non-
sustained VT.
• He was seen for evaluation of syncope and delivery of an electric shock.
FastPath Summery: Quick look overview
Episode Summary: Any VT/VF episode? Therapy delivered?
Diagnostics Summary: How many % paced or sensed?
Parameters: Zone, rate cut-off, # of interval for detection,
discriminators and therapies programmed
Parameters: ATP and dynamic sensitivity details
Episode Details:
Diagnosis of discriminators: VT or SVT?
What therapies have been delivered? ATP or shock?
Burst or Ramp ?
Successful or failed?
1
2
3
4 5
Observe from Tracing
Observe from Tracing
Sudden onset of a regular monomorphous tachycardia, with change in
morphology; probable VT; initial cycles classified unbinned because of
discordance between the instantaneous (fast) and average of the 4 previous
cycles (slow)
After 16 T classified cycles, the VT counter if full
First therapy corresponding to the VT zone; it is a ramp (pacing with cycles
shortening from 252 to 200 ms)
Instead of termination, the ventricular rhythm is markedly accelerated,
detected in the VF zone and become polymorphous
After 12 F classified cycles, an episode of VF is detected; the capacitors begin
to charge
2
3
4
5
1
6 7
Observe from Tracing
End of charge and delivery of 30 J shock
End of arrhythmia and return to sinus rhythm diagnosed
7
6
Comments
• This patient had ischemic cardiomyopathy with multiple episodes of
asymptomatic or nearly asymptomatic NSVT (4 to 20 cycles).
• Never experienced an episode of sustained VT or of syncope before the
implantation.
• After implant, he presented loss of consciousness and electric shock in
absence of apparent triggering factor.
• Interrogation revealed many episodes of NSVT, as well as a few episodes
treated by ATP and a single episode treated by a shock.
• Tracing revealed a proarrhythmic effect of the ramp and acceleration of
stable VT to a rapid, polymorphous ventricular arrhythmia causing syncope
and terminated by a life-saving electric shock.
• The priority in the management of these episodes of NSVT was to promote
their spontaneous termination, and to program a sufficient number of
cycles to avoid this undesirable outcome.
• If acceleration of an arrhythmia is an immediate risk, it should be terminated
with one maximum energy shock to avoid the delivery of multiple electric
shocks as this will compromise the survival in long-term.
• The device programming was, therefore, modified by an increase in the number
of cycles needed to fill the counters, from 16 to 30 in the VT, and from 12 to 30
in the VF zones. This should offer a wide enough margin and promote a
spontaneous termination without increasing significantly the risk of syncope,
should the tachyarrhythmia be sustained.
• The first therapy in the VT zone was a ramp, which may be surprising and
against the latest guidelines, which clearly favor the programming of bursts,
apparently more effective from the standpoint of the
terminations/accelerations ratio.
• Furthermore, the coupling and the decrement of that ramp were probably both
excessively aggressive, since the last pulse was delivered at the shortest
coupling interval of 200 ms.
• The programming was replaced by 3 bursts, followed by the highest amplitude
shocks in the VT zone.
Comments
Wr
Wrap-up Overview: What parameters have been changed?
• ICD is a medical breakthrough but has a complex functioning
• Adequate therapy prolongs survival but unnecessary therapy
increases morbidity and mortality
• Appropriate function requires adequate mechanical
components (Lead), electrical function (battery and
capacitor), software functioning (detection algorithms), and
substrate (appropriate DFT and safety margin)
• Knowledge and know-how of all 4 components of ICD therapy
is essential for the caregiver
Thank you

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How to read ICD episode_Dr Kush Bhagat.pptx

  • 1. How to read ICD episode?
  • 2. ICD Follow Up Standard • ICD/CRT-D: 3-6 Months Suggested • Battery Voltage (and Impedance) • Capacitor Charge Time • Pacing and sensing threshold(s) for atrium, right and left ventricle (all leads) • Pacing lead impedance(s) for all leads • Shocking Impedances for defibrillation leads • Arrhythmias detected by device • % of pacing/sensing in each chamber • Therapies required for termination of SVT/VT/VF • Review of main programmed parameters • Review of any device triggered alerts • Review of hemodynamic measurements when available * Wilkoff BL, Auricchio A, et al - HRS/EHRA Expert Consensus on the Monitoring of Cardiovascular Implantable Electronic Devices (CIED): Description of Techniques, Indications, Personnel, Frequency and Ethical Considerations - May 14, 2008
  • 3. Episodes Review • Start with the VF episodes/Therapy Delivred Episodes • Consider the device warnings • For each episode check: • if it is a “true” (clinical) VT/VF • the detection • the therapy • Special Functions • Other factors can influence your judgement • Preceding symptoms • Palpitations (irregular -> AF, regular -> SVT, VT) • Changes in medications • Recent reprogramming • Other diseases (co-morbidities)
  • 5. Almost everything at first Sight ... 1. Present Rhythm and Rate 5. Episodes 4. Device observations / Warnings 3. Lead(s) Status 2. Battery and Capacitors
  • 6. Stored Episode Review Read episodes and analyze •Related Patient symptoms •Did discriminators give correct diagnosis? •Appropriate or Inappropriate therapies? •Single Episode or Multiple Read episodes and analyze •Check for Episode Initiation •Check for terminations
  • 8. Inappropriate Shock Tachycardia Absent (Over sensing) Intracardiac T/P wave Double count Extracardiac EMI Myopotentials Present (Inappropriate SVT detection)
  • 9. The ICD EGM Signal • Nearfield • Electrodes are close in range • EGM Source = Tip-to-Ring / Tip-to-Coil • Narrow signal – less myocardium in range • Used for arrhythmia detection Farfield Electrodes are further in range EGM Source = Variable More myocardium covered in range Can resemble surface EKG SINUS RHYTHM VT ICD always uses a Near Field EGM source for sensing and detection to avoid oversensing
  • 12. Myopotentials •Myopotentials are high-frequency, low-amplitude electrical transients generated by skeletal muscles, including inter-costal muscles or the diaphragm. Electrograms from a stored episode showing noise on the electrogram recorded between the SVC coil and pulse generator, and the absence of noise on the V sense/pace signal (right ventricular tip to right ventricular ring).
  • 13. Skeletal muscle oversensing Different sensing configurations during isometric left arm exercise showing noise seen only when the pulse generator was part of the recording suggesting that the signals are originating from in or near the pocket. •Provocative skeletal isometric exercise involving the upper extremities and abdominal muscles •Absence of noise when can is removed from the sensing circuit
  • 14. Diaphragmatic myo- potentials diaphragmatic myopotentials presents as low-amplitude, high frequency signals most of the time detected exclusively in the near-field channel with no alteration in the shock electrogram. (Top) Diaphragmatic myopotential oversensing during Valsalva manoeuvre with sensitivity programmed in nominal: stored right ventricular and shock electrograms. (Bottom) Abolishment of oversensing during Valsalva manoeuvre with sensitivity programmed in least: stored right ventricular and shock electrograms.
  • 15. NSVT EGM Recorded by Device due to oversensing : (Early Lead Warning ) P wave oversensing- Due to lead Dislodgement in Acute Phase Oversensing in Near Field EGM
  • 16. ICD Ventricular Oversensing: Intracardiac Oversensing TWOS: T wave Oversensing
  • 17. Enhanced Filter and Special Sensing Parameters to Avoid TWOS DYNAMIC SENSITIVITY ADJUSTMENT
  • 18. Features to minimize T-wave oversensing
  • 20. Lead Problems :Lead failure • It occurs during a small fraction (,8%) of the cardiac cycle •The pacing-lead impedance may be abnormal and intermittent. •signals are intermittent and have a Low frequency. •Usually, at least some signals are not cyclic. • Often, some intervals are nonphysiological, shorter than typical physiological intervals. • It often saturates the amplifier that often Signal amplitude may exceed the range of the sensing amplifier and thus appear truncated.
  • 21. Lead Noise vs True VT/VF Episodes
  • 22. Proprietary and confidential — do not distribute Clinical presentation Noise VF RV Near Field channel Discrimination channel (RV coil – can): Rate Correlation NO YES Technical complication Oversensing None Decision of SecureSense™ Inhibit therapy Deliver therapy • Detects and differentiates lead noise from a real VT/VF thanks to a rate comparison between the near field channel and a new reference channel (called discrimination channel) • Discrimination of lead noise in VT zone as well as in VF zone • Also able to detect non- sustained RV noises Lead Noise Discriminator : Functional principles • lead noise often generated by the following complications : Pace/Sense lead fracture Insulator rupture Loose set screw Lead not seated properly in connector
  • 24. Tachycardia present • VF? – Analyse EGM to verify • VT? – Analyse EGM to differentiate SVT/VT
  • 25. Shock Tachycardia Duration/ no. intervals Ignore non- sustained Detection Enhance-ments Discrimin-ation Ignore SVT • Morphology onset, stability, other logic • Single/dual chamber ATP • Terminate VT • Allow time  self- term • Terminate some SVT VT Ignore slow rhythms (VT, SVT) Heart rate threshold
  • 26. Characteristics real VT vs SVT A-Fib/Flutter Sinus Tach Other 1:1 SVT 200 bpm 200 bpm 200 bpm 200 bpm VT Fast V-V Cycle Length Due To… Onset Stability EGM Morphology Sudden Regular Wide / Different QRS Gradual Sudden Sudden Narrow/ Normal QRS Narrow/ Normal QRS Narrow/ Normal QRS Irregular Regular Regular
  • 27. EGM to differentiate SVT/VT • Single chamber ICD – Unstable rhythm is more likely to represent AF, – Gradual acceleration is more compatible with sinus tachycardia – Sudden onset regular tachycardias – SVT (AVNRT, AT, Afl) or VT • Compare morphology of far-field channel from sinus rhythm with the one in arrhythmia • Morphology of beats that immediately follow shocks should not be relied on for comparison because of possible EGM distortion ATP
  • 28. EGM to differentiate SVT/VT • ATP response • In V=A Tachycardia, During ATP – If AV dissociation – AT > AVNRT >> VT – If retrograde AV blocks – AVNRT > VT – Arrhythmia termination by ATP – supports VT >> AVRT, AVNRT – If atrial acceleration to ATP (entrainment), then after ATP stops • VAAV – AT • VVA – VT • VAV – Not helpful
  • 29. EGM to differentiate SVT/VT • Dual chamber ICD – Atrial sensing • V>A vs. V<A • PVC vs. PAC initiated • If V=A, Driving chamber – A-A followed by V-V vs. V-V followed by A-A Chamber Onset ATP
  • 31. Appropriate Shock • Single shock • Multiple shocks – Ineffective Initial shocks – High DFT – Incessant VT – VT Storm – Appropriate shocks for AF – If AF defibrillation ‘ON’
  • 32. Multiple shocks / VT storm
  • 33. Multiple shocks / VT storm
  • 34. “VT Storm / Electrical Storm” • Clustering episodes of VT/VF in a short amount of time • “Electrical Storm” defined as > 3 VT episodes treated by ICD within a 24 hour period • 10 – 20% of ICD patients
  • 35. Electrical Storm: ≥3 VA/24 Hours Reversible Causes AAD Catheter Ablation Neural Modulation Palliation/ Replacement Therapies •K blocker •Na blocker •β blocker •Triggers •Substrate modification • Cooling • Anesthesia • Stellate blocks • Denervation surgery •Team approach •Electrolytes •Ischemia •Inflammation •Triggers
  • 36. VT storm • Treat ischemia or other precipitating factors such as HF • Judicious use of a magnet or inactivation of ICD therapy • Pharmacological therapy for VT (e.g. β-blockers, amiodarone); possible catheter ablation • IABP or hemodynamic support for hypotension • Replace electrolytes (K+, Mg2+) • Left stellate ganglionic blockade in selected patients • Identify specific diseases that may need specific therapy (e.g. recurrent VT in Brugada syndrome - isoproterenol and quinidine)
  • 37. SYNCOPE WITH NO APPARENT SHOCK
  • 40. Background • 67-year-old man implanted with a single-chamber ICD for the management of advanced ischemic cardiomyopathy complicated by repetitive episodes of non- sustained VT. • He was seen for evaluation of syncope and delivery of an electric shock.
  • 41. FastPath Summery: Quick look overview
  • 42. Episode Summary: Any VT/VF episode? Therapy delivered?
  • 43. Diagnostics Summary: How many % paced or sensed?
  • 44. Parameters: Zone, rate cut-off, # of interval for detection, discriminators and therapies programmed
  • 45. Parameters: ATP and dynamic sensitivity details
  • 46. Episode Details: Diagnosis of discriminators: VT or SVT? What therapies have been delivered? ATP or shock? Burst or Ramp ? Successful or failed?
  • 48. Observe from Tracing Sudden onset of a regular monomorphous tachycardia, with change in morphology; probable VT; initial cycles classified unbinned because of discordance between the instantaneous (fast) and average of the 4 previous cycles (slow) After 16 T classified cycles, the VT counter if full First therapy corresponding to the VT zone; it is a ramp (pacing with cycles shortening from 252 to 200 ms) Instead of termination, the ventricular rhythm is markedly accelerated, detected in the VF zone and become polymorphous After 12 F classified cycles, an episode of VF is detected; the capacitors begin to charge 2 3 4 5 1
  • 49. 6 7
  • 50. Observe from Tracing End of charge and delivery of 30 J shock End of arrhythmia and return to sinus rhythm diagnosed 7 6
  • 51. Comments • This patient had ischemic cardiomyopathy with multiple episodes of asymptomatic or nearly asymptomatic NSVT (4 to 20 cycles). • Never experienced an episode of sustained VT or of syncope before the implantation. • After implant, he presented loss of consciousness and electric shock in absence of apparent triggering factor. • Interrogation revealed many episodes of NSVT, as well as a few episodes treated by ATP and a single episode treated by a shock. • Tracing revealed a proarrhythmic effect of the ramp and acceleration of stable VT to a rapid, polymorphous ventricular arrhythmia causing syncope and terminated by a life-saving electric shock. • The priority in the management of these episodes of NSVT was to promote their spontaneous termination, and to program a sufficient number of cycles to avoid this undesirable outcome.
  • 52. • If acceleration of an arrhythmia is an immediate risk, it should be terminated with one maximum energy shock to avoid the delivery of multiple electric shocks as this will compromise the survival in long-term. • The device programming was, therefore, modified by an increase in the number of cycles needed to fill the counters, from 16 to 30 in the VT, and from 12 to 30 in the VF zones. This should offer a wide enough margin and promote a spontaneous termination without increasing significantly the risk of syncope, should the tachyarrhythmia be sustained. • The first therapy in the VT zone was a ramp, which may be surprising and against the latest guidelines, which clearly favor the programming of bursts, apparently more effective from the standpoint of the terminations/accelerations ratio. • Furthermore, the coupling and the decrement of that ramp were probably both excessively aggressive, since the last pulse was delivered at the shortest coupling interval of 200 ms. • The programming was replaced by 3 bursts, followed by the highest amplitude shocks in the VT zone. Comments
  • 53. Wr Wrap-up Overview: What parameters have been changed?
  • 54. • ICD is a medical breakthrough but has a complex functioning • Adequate therapy prolongs survival but unnecessary therapy increases morbidity and mortality • Appropriate function requires adequate mechanical components (Lead), electrical function (battery and capacitor), software functioning (detection algorithms), and substrate (appropriate DFT and safety margin) • Knowledge and know-how of all 4 components of ICD therapy is essential for the caregiver