This document defines and classifies different types of outcomes in healthcare research. It discusses short, intermediate, and long-term outcomes as well as care-related, patient-related, and performance-related outcomes. Positive outcomes in patient-centered outcomes research aim to incorporate diverse participants and address individual needs and preferences related to survival, function, and quality of life. Negative outcomes can occur when industry sponsors clinical research, introducing potential bias favoring their products. Proper outcomes measurement involves determining measures of interest, gathering data, analyzing results, interpreting outcomes, making changes, and remeasuring to evaluate effectiveness.