Matt Raible compares the Java web frameworks Micronaut, Quarkus, and Spring Boot for building REST APIs. He demonstrates how to quickly get started with each framework, secure APIs with OAuth 2.1 and JWTs, build Docker images, and go native with GraalVM. Performance tests show Quarkus has the fastest startup time while Spring Boot has the largest community support in areas like Stack Overflow questions, GitHub stars, and jobs on Indeed.