Bootstrap is an open-source front-end framework for building responsive mobile-first sites and apps. It contains HTML and CSS templates for common elements like navigation, buttons, forms, and a grid system, as well as optional JavaScript plugins. Bootstrap's main advantages are that it is easy to use, responsive, mobile-first, and compatible with all modern browsers. The core Bootstrap files include bootstrap.css for styling, bootstrap.js for JavaScript plugins, and glyphicons for icons. It also requires jQuery. Developers can include Bootstrap from a CDN or download it from the Bootstrap website.