Saad Rashid Usmani
Nuclear medicine and radiotherapy
Radiation Therapy
The use of high-energy rays to
damage cancer cells, stopping
them from growing and
dividing.
Grenz: 10-15 kVp
Contact: 50 kVp
Superficial: 50-150 kVp
Orthovoltage: 150-500 kVp
Super Voltage: 500 to 1,000 kV
Mega voltage: more than 1 Mev
3
Radiation Therapy
Cobalt-60
Machines
linear accelerator
The overall diameter of a 60Co source is 1 to 3
centimeters.
Radioactive 60Co enclosed in multiple layers of
welded metal to prevent contamination of the
environment and to absorb β- particles
produced by the decay process.
6
60Co Source
linear accelerator
Smaller source with less penumbra for the
same beam intensity
Less hazard of contamination should a
source ever become exposed to the
environment.
Advantages:
Cobalt 60 sources have an activity of 750-9000 Ci.
Typically 3000-9000 Ci used in radiation therapy.
9
60Co Activity
Half-life: the time necessary for a radioactive material
to decay to half or 50% of its original intensity.
10
Half-life
The half-life of 60Co is
5.26 years
12
Cobalt-60 Production
Cobalt-60, or Co-60, is an unstable isotope of cobalt.
It is radioactive.
Co-60 is made by a process called neutron activation.
In activation, a cobalt (cobalt-59) put into an operating
nuclear reactor and exposed to the neutron flux.
The cobalt-59 will absorb a neutron and become
cobalt-60, and the sample (now called a source) is then
withdrawn from the reactor and put into a heavily
shielded casket for storage.
Neutron activation
of Cobalt 59
linear accelerator
linear accelerator
linear accelerator
linear accelerator
linear accelerator
linear accelerator
linear accelerator
linear accelerator
Cobalt machine consists of
following major system
Cobalt source head
Treatment table
Collimator
linear accelerator
Cobalt source head
This is the main part of the system because it contain the
source
20cm to 25cm is the thickness of head of most cobalt units.
Uses a counterweight to balance the lead
shielding in the head of the machine housing,
(similar to the beam stopper on linac): absorbs
a significant amount of radiation transmitted
through patient.
60Co Shielding
It consists of a steel shell filled with
lead for shielding purposes and a
device for bringing the source in
front of an opening in the head
from which the useful beam
emerges.
Also, a heavy metal alloy sleeve is
provided to form an additional
primary shield when the source is in
the off position.
Cerrobend (Lipowitz metal):
50% Bismuth
26.7% Lead
13.3% tin
10% Cadmium (a toxic metal can get into
bloodstream)
A thickness of 7.2 cm of Cerrobend needed, 6 cm lead.
27
60Co Shielding
Dose maximum (Dmax): when a greater
percentage of dose occurs below the skin
surface
Dmax is the depth of maximum buildup, in
which 100% of the dose is deposited.
For 60Co, Dmax occurs at 0.5 cm below the skin
surface.
28
Dose Maximum
On and off position of
source
linear accelerator
Collimator
Types of collimator present that can make beam with rectangular cross
section area
linear accelerator
Treatment table
The patient lies on
couch which can be
moves upwards
downwards and side
ways also so that
tumor is positioned
and the beam will
pass through the
tumor
linear accelerator
The 60Co unit is commonly used today to treat cancers
of the head and neck area, breast, spine, and
extremities.
Areas just below the skin surface.
Ideal in treating lymph nodes.
A 60Co beam can provide an adequate distribution of
dose by using parallel opposed fields.
37
Application
Disadvantages as compare to
linear accelerator
Required to stored high activity source, and on going
cost of source replacement
The source diameter is 2 cm as compare to linear
accelerator target is is big so have got big penumbra
Low dose rate as compare to linear accelerator
Limited photon energy as compare to linear
accelerator
Any Question 
     Thank 
    you   
        
     

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linear accelerator

  • 1. Saad Rashid Usmani Nuclear medicine and radiotherapy
  • 2. Radiation Therapy The use of high-energy rays to damage cancer cells, stopping them from growing and dividing.
  • 3. Grenz: 10-15 kVp Contact: 50 kVp Superficial: 50-150 kVp Orthovoltage: 150-500 kVp Super Voltage: 500 to 1,000 kV Mega voltage: more than 1 Mev 3 Radiation Therapy
  • 6. The overall diameter of a 60Co source is 1 to 3 centimeters. Radioactive 60Co enclosed in multiple layers of welded metal to prevent contamination of the environment and to absorb β- particles produced by the decay process. 6 60Co Source
  • 8. Smaller source with less penumbra for the same beam intensity Less hazard of contamination should a source ever become exposed to the environment. Advantages:
  • 9. Cobalt 60 sources have an activity of 750-9000 Ci. Typically 3000-9000 Ci used in radiation therapy. 9 60Co Activity
  • 10. Half-life: the time necessary for a radioactive material to decay to half or 50% of its original intensity. 10 Half-life
  • 11. The half-life of 60Co is 5.26 years
  • 12. 12 Cobalt-60 Production Cobalt-60, or Co-60, is an unstable isotope of cobalt. It is radioactive. Co-60 is made by a process called neutron activation. In activation, a cobalt (cobalt-59) put into an operating nuclear reactor and exposed to the neutron flux. The cobalt-59 will absorb a neutron and become cobalt-60, and the sample (now called a source) is then withdrawn from the reactor and put into a heavily shielded casket for storage.
  • 22. Cobalt machine consists of following major system Cobalt source head Treatment table Collimator
  • 25. This is the main part of the system because it contain the source 20cm to 25cm is the thickness of head of most cobalt units. Uses a counterweight to balance the lead shielding in the head of the machine housing, (similar to the beam stopper on linac): absorbs a significant amount of radiation transmitted through patient.
  • 26. 60Co Shielding It consists of a steel shell filled with lead for shielding purposes and a device for bringing the source in front of an opening in the head from which the useful beam emerges. Also, a heavy metal alloy sleeve is provided to form an additional primary shield when the source is in the off position.
  • 27. Cerrobend (Lipowitz metal): 50% Bismuth 26.7% Lead 13.3% tin 10% Cadmium (a toxic metal can get into bloodstream) A thickness of 7.2 cm of Cerrobend needed, 6 cm lead. 27 60Co Shielding
  • 28. Dose maximum (Dmax): when a greater percentage of dose occurs below the skin surface Dmax is the depth of maximum buildup, in which 100% of the dose is deposited. For 60Co, Dmax occurs at 0.5 cm below the skin surface. 28 Dose Maximum
  • 29. On and off position of source
  • 32. Types of collimator present that can make beam with rectangular cross section area
  • 35. The patient lies on couch which can be moves upwards downwards and side ways also so that tumor is positioned and the beam will pass through the tumor
  • 37. The 60Co unit is commonly used today to treat cancers of the head and neck area, breast, spine, and extremities. Areas just below the skin surface. Ideal in treating lymph nodes. A 60Co beam can provide an adequate distribution of dose by using parallel opposed fields. 37 Application
  • 38. Disadvantages as compare to linear accelerator Required to stored high activity source, and on going cost of source replacement The source diameter is 2 cm as compare to linear accelerator target is is big so have got big penumbra Low dose rate as compare to linear accelerator Limited photon energy as compare to linear accelerator
  • 40.      Thank      you                  