Cobalt-60 is produced by neutron activation of cobalt-59 in nuclear reactors. It is used as a gamma ray source in radiation therapy. A cobalt-60 therapy machine consists of a cobalt source head that houses the radioactive cobalt-60 source, a treatment table, and a collimator. The cobalt-60 source has a diameter of 1-3 cm and is enclosed in multiple metal layers for shielding. It is used to treat cancers in areas close to the skin like the head, neck, breast, and extremities. Advantages include treating lymph nodes, but disadvantages are the need for source replacement and lower dose rates compared to linear accelerators.