1
Liver
Function
Test
Specific Learning objectives
At the end of the lecture students will be able to
• Describe the liver function test
• Uses of liver function test
Liver function test
• Liver function tests, also known as liver chemistries, help
determine the health of your liver by measuring the
levels of proteins, liver enzymes, and bilirubin in blood.
They can also monitor the progression or treatment of
an existing disease.
• Depending on the test, either higher- or lower-than-
typical levels of these enzymes or proteins can indicate a
problem with your liver.
• A liver function test is often recommended in the
following situations:
• to check for damage from liver infections, such
as hepatitis Band hepatitis C, especially if it’s suspected
you were exposed to a virus that causes hepatitis
• to monitor the side effects of certain medications
because some medications are known to affect the liver,
including:
• NSAIDsTrusted Source
• statins
• antibiotics
• antiseizure medications
• tuberculosis drugs
• if you already have liver disease, to monitor the disease
and how well a particular treatment is working
• experiencing the symptoms of a liver disorder or have a
family history of a liver disease, such as fattyliver
disease
• have certain medical conditions, such as:
• high triglycerides
• diabetes
• high blood pressure
• anemia
• drink alcohol frequently
• gallbladder disease
Major functions of liver
1.Metabolic functions : Liver actively participates in
carbohydrate, lipid, protein, mineral and vitamin
metabolisms.
2. Excretory functions : Bile pigments, bile salts and
cholesterol are excreted in the bile into intestine.
3. Protective functions and detoxification : Kupffer cells
of liver perform phagocytosis to eliminate foreign
compounds. Ammonia is detoxified to urea. Liver is
responsible for the metabolism of xenobiotics
4. Hematological functions : Liver participates in the
formation of blood (particularly in the embryo), synthesis
of plasma proteins (including blood clotting factors) and
destruction of erythrocytes.
5. Storage functions : Glycogen, vitamins A, D and B12
and trace element iron are stored in liver
Types of liver function tests
Liver function tests are used to measure specific enzymes
and proteins in blood.
• Alanine transaminase (ALT) test
• Aspartate aminotransferase (AST) test
• Alkaline phosphatase (ALP) test
• Albumin test
• Bilirubin test
Alanine transaminase (ALT) test
• Alanine transaminase (ALT)is used by your body to
metabolize protein. If the liver is damaged or not
functioning properly, ALT can be released into the blood.
This causes ALT levels to increase. A higher result than
what’s typical on this test can be a sign of liver damage.
• It’s estimated that about 10 percent of people in the United
States have elevated ALT levels.
Aspartate aminotransferase (AST) test
• Aspartate aminotransferase (AST) is an enzyme found
in several parts of your body, including your:
• heart
• brain
• pancreas
• liver
• muscles
• When the liver is damaged, AST can be released into
the bloodstream. A high result on an AST test might
indicate a problem with the liver or muscles.
Alkaline phosphatase (ALP) test
• Alkaline phosphatase (ALP)is an enzyme found in your bones,
bile ducts, and liver.
• An ALP test is typically ordered in combination with several
other tests.
• An ALP test can be used to evaluate the bile duct system of
the liver.
Albumin test
• Albumin is the main protein made by your liver. It performs
many important bodily functions.
• For example, albumin nourishes your tissues and transports
hormones, vitamins, and other substances throughout your
body. An albumin test measures how well your liver is making
this particular protein.
Bilirubin test
• Bilirubin is a waste product from the breakdown of red blood
cells. It’s ordinarily processed by the liver. It passes through
the liver before being excreted through your stool.
• A damaged liver can’t properly process bilirubin. This leads to
an atypically high level of bilirubin in the blood. Certain
inherited diseases can raise bilirubin levels, even when liver
function works as expected.
Preparation for a liver function test
Give complete instructions on how to prepare for the blood
sample portion of the test.
• Certain medications and foods may affect levels of these
enzymes and proteins in your blood.
• Doctor may ask you to avoid some types of medications, or
they may ask you to avoid eating anything for a period of
time before the test.
• Be sure to continue drinking water prior to the test.
• may want to wear a shirt with sleeves that can easily be
rolled up to make it easier for the medical expert to collect
the blood sample.
liver function test performed
• The healthcare technician will clean your skin before
the test to decrease the likelihood that any
microorganisms on your skin will cause an infection.
• They’ll likely wrap an elastic strap on your arm. This
will help your veins become more visible.
• They’ll then use a needle to draw samples of blood
from your arm.
• After the draw, the
technician will place some
gauze and a bandage over
the puncture site.
• Your blood sample will be
sent to a laboratory for
testing.
Expected Question
Essay Situation Question
Explain liver function test
Short Question
Explain the type of liver function test
Explain normal range of test
THANK YOU

Liver Function Test_Nursing.pptx for nursing

  • 1.
  • 2.
    Specific Learning objectives Atthe end of the lecture students will be able to • Describe the liver function test • Uses of liver function test
  • 3.
    Liver function test •Liver function tests, also known as liver chemistries, help determine the health of your liver by measuring the levels of proteins, liver enzymes, and bilirubin in blood. They can also monitor the progression or treatment of an existing disease. • Depending on the test, either higher- or lower-than- typical levels of these enzymes or proteins can indicate a problem with your liver.
  • 4.
    • A liverfunction test is often recommended in the following situations: • to check for damage from liver infections, such as hepatitis Band hepatitis C, especially if it’s suspected you were exposed to a virus that causes hepatitis
  • 5.
    • to monitorthe side effects of certain medications because some medications are known to affect the liver, including: • NSAIDsTrusted Source • statins • antibiotics • antiseizure medications • tuberculosis drugs • if you already have liver disease, to monitor the disease and how well a particular treatment is working
  • 6.
    • experiencing thesymptoms of a liver disorder or have a family history of a liver disease, such as fattyliver disease • have certain medical conditions, such as: • high triglycerides • diabetes • high blood pressure • anemia • drink alcohol frequently • gallbladder disease
  • 7.
    Major functions ofliver 1.Metabolic functions : Liver actively participates in carbohydrate, lipid, protein, mineral and vitamin metabolisms. 2. Excretory functions : Bile pigments, bile salts and cholesterol are excreted in the bile into intestine. 3. Protective functions and detoxification : Kupffer cells of liver perform phagocytosis to eliminate foreign compounds. Ammonia is detoxified to urea. Liver is responsible for the metabolism of xenobiotics
  • 8.
    4. Hematological functions: Liver participates in the formation of blood (particularly in the embryo), synthesis of plasma proteins (including blood clotting factors) and destruction of erythrocytes. 5. Storage functions : Glycogen, vitamins A, D and B12 and trace element iron are stored in liver
  • 9.
    Types of liverfunction tests Liver function tests are used to measure specific enzymes and proteins in blood. • Alanine transaminase (ALT) test • Aspartate aminotransferase (AST) test • Alkaline phosphatase (ALP) test • Albumin test • Bilirubin test
  • 10.
    Alanine transaminase (ALT)test • Alanine transaminase (ALT)is used by your body to metabolize protein. If the liver is damaged or not functioning properly, ALT can be released into the blood. This causes ALT levels to increase. A higher result than what’s typical on this test can be a sign of liver damage. • It’s estimated that about 10 percent of people in the United States have elevated ALT levels.
  • 11.
    Aspartate aminotransferase (AST)test • Aspartate aminotransferase (AST) is an enzyme found in several parts of your body, including your: • heart • brain • pancreas • liver • muscles • When the liver is damaged, AST can be released into the bloodstream. A high result on an AST test might indicate a problem with the liver or muscles.
  • 12.
    Alkaline phosphatase (ALP)test • Alkaline phosphatase (ALP)is an enzyme found in your bones, bile ducts, and liver. • An ALP test is typically ordered in combination with several other tests. • An ALP test can be used to evaluate the bile duct system of the liver.
  • 13.
    Albumin test • Albuminis the main protein made by your liver. It performs many important bodily functions. • For example, albumin nourishes your tissues and transports hormones, vitamins, and other substances throughout your body. An albumin test measures how well your liver is making this particular protein.
  • 14.
    Bilirubin test • Bilirubinis a waste product from the breakdown of red blood cells. It’s ordinarily processed by the liver. It passes through the liver before being excreted through your stool. • A damaged liver can’t properly process bilirubin. This leads to an atypically high level of bilirubin in the blood. Certain inherited diseases can raise bilirubin levels, even when liver function works as expected.
  • 17.
    Preparation for aliver function test Give complete instructions on how to prepare for the blood sample portion of the test. • Certain medications and foods may affect levels of these enzymes and proteins in your blood. • Doctor may ask you to avoid some types of medications, or they may ask you to avoid eating anything for a period of time before the test.
  • 18.
    • Be sureto continue drinking water prior to the test. • may want to wear a shirt with sleeves that can easily be rolled up to make it easier for the medical expert to collect the blood sample.
  • 19.
    liver function testperformed • The healthcare technician will clean your skin before the test to decrease the likelihood that any microorganisms on your skin will cause an infection. • They’ll likely wrap an elastic strap on your arm. This will help your veins become more visible. • They’ll then use a needle to draw samples of blood from your arm.
  • 20.
    • After thedraw, the technician will place some gauze and a bandage over the puncture site. • Your blood sample will be sent to a laboratory for testing.
  • 21.
    Expected Question Essay SituationQuestion Explain liver function test Short Question Explain the type of liver function test Explain normal range of test
  • 22.