This document discusses various nerve blocks used for mandibular anesthesia, including the inferior alveolar nerve block, Gow-Gates technique, Vazirani-Akinosi closed-mouth block, and mental nerve block. It describes the nerves anesthetized, areas anesthetized, indications, contraindications, landmarks, techniques, and potential complications for each block. The inferior alveolar nerve block and Gow-Gates technique provide the most extensive mandibular anesthesia while the mental nerve block specifically targets the area innervated by the mental nerve. Proper administration of these blocks requires identifying the correct anatomical landmarks and depositing the local anesthetic in the appropriate location near the target nerve.