Mechanisms of Drug Action (PH 1.8) - Complete Pharmacology Flowcharts

Mechanisms of Drug Action (PH 1.8) - Complete Pharmacology Flowcharts

• 1.
  📋 TABLE OFCONTENTS 1 ADRENALINE 2 ATROPINE 3 NEOSTIGMINE 4 PROPRANOLOL 5 PRAZOSIN 6 ENALAPRIL 7 LOSARTAN 8 AMLODIPINE 9 DIGOXIN 10 FUROSEMIDE 11 NITROPRUSSIDE 12 DIAZEPAM Sympathomimetic Anticholinergic Cholinesterase Inhibitor β-Blocker α₁-Blocker ACE Inhibitor ARB Calcium Channel Blocker Cardiac Glycoside Loop Diuretic Vasodilator Benzodiazepine PHARMACOLOGY FLOWCHARTS Complete Collection: Mechanisms of Drug Action www.clinpharma.weebly.com ↑
• 2.
  13 FLUOXETINE 14 MORPHINE 15 ASPIRIN 1 ADRENALINE Class: Sympathomimetic Use:Anaphylaxis, Cardiac arrest Action: Stimulates α and β receptors SSRI Opioid NSAID ADRENALINE 1 Binds to α and β Adrenergic Receptors 2 α₁ Receptors (Blood vessels) 3 β₁ Receptors (Heart) 4 β₂ Receptors (Lungs) 5 Vasoconstriction 6 ↑Heart Rate ↑Force 7 Bronchodilation 8 ↑Blood Pressure ↑Cardiac Output Better Breathing 9
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  2 ATROPINE Class: Anticholinergic Use:Bradycardia, Poisoning Action: Blocks muscarinic receptors ATROPINE 1 Blocks Muscarinic Receptors 2 Prevents Acetylcholine Action 3 ↓Parasympathetic Activity 4 ↑Heart Rate 5 Dry Mouth 6 Dilated Pupils 7
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  3 NEOSTIGMINE Class: CholinesteraseInhibitor Use: Myasthenia gravis Action: Increases acetylcholine NEOSTIGMINE 1 Inhibits Acetylcholinesterase 2 ↓ACh Breakdown 3 ↑ACh at Synapse 4 ↑Cholinergic Activity 5 ↑Muscle Contraction ↑Parasympathetic Effects 6
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  4 PROPRANOLOL Class: β-Blocker Use:Hypertension, Angina Action: Blocks β receptors PROPRANOLOL 1 Blocks β₁ and β₂ Receptors 2 Prevents Adrenaline/ Noradrenaline Action 3 β₁ Block (Heart) 4 β₂ Block (Lungs/Vessels) 5 ↓Heart Rate ↓Force 6 May cause Bronchospasm 7 ↓Blood Pressure ↓Oxygen Demand 8
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  5 PRAZOSIN Class: α₁-Blocker Use:Hypertension, BPH Action: Blocks α₁ receptors PRAZOSIN 1 Blocks α₁ Receptors 2 ↓Calcium Entry 3 Smooth Muscle Relaxation 4 Blood Vessel Dilation 5 Prostate Relaxation 6 ↓Blood Pressure Better Urine Flow 7
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  6 ENALAPRIL Class: ACEInhibitor Use: Hypertension, Heart failure Action: Blocks angiotensin formation ENALAPRIL 1 Inhibits ACE Enzyme 2 ↓Angiotensin II Formation 3 ↑Bradykinin Levels 4 Vasodilation ↓Aldosterone 5 Dry Cough (Side Effect) 6 ↓Blood Pressure ↓Fluid Retention 7
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  7 LOSARTAN Class: ARB(Angiotensin Receptor Blocker) Use: Hypertension Action: Blocks angiotensin receptors LOSARTAN 1 Blocks AT₁ Receptors 2 Prevents Angiotensin II Effects 3 No Vasoconstriction 4 ↓Aldosterone 5 ↓Blood Pressure No Cough 6
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  8 AMLODIPINE Class: CalciumChannel Blocker Use: Hypertension, Angina Action: Blocks calcium channels AMLODIPINE 1 Blocks L-type Calcium Channels 2 ↓Calcium Entry into Cells 3 Smooth Muscle Relaxation 4 Vasodilation (Mainly Arteries) 5 ↓Blood Pressure ↓Heart Workload 6
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  9 DIGOXIN Class: CardiacGlycoside Use: Heart failure, AF Action: Increases heart contractility DIGOXIN 1 Inhibits Na⁺/K⁺ Pump 2 ↑Sodium Inside Cell 3 ↑Calcium Inside Cell 4 ↑Heart Contractility 5 ↓Heart Rate (Vagal effect) 6 Improved Pumping Better Cardiac Output 7
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  10 FUROSEMIDE Class: LoopDiuretic Use: Edema, Hypertension Action: Increases urine output FUROSEMIDE 1 Blocks NKCC2 in Loop of Henle 2 ↓Salt Reabsorption 3 ↓Water Reabsorption 4 ↑Urine Output 5 K⁺ Loss 6 ↓Blood Volume ↓Blood Pressure 7
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  11 NITROPRUSSIDE Class: Vasodilator Use:Hypertensive emergency Action: Direct vessel relaxation NITROPRUSSIDE 1 Releases NO (Nitric Oxide) 2 ↑cGMP in Smooth Muscle 3 Muscle Relaxation 4 Arterial Dilation 5 Venous Dilation 6 Rapid ↓BP Watch for CN⁻ toxicity 7
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  12 DIAZEPAM Class: Benzodiazepine Use:Anxiety, Seizures Action: Enhances GABA DIAZEPAM 1 Binds to GABA-A Receptor 2 Enhances GABA Effect 3 ↑Chloride Entry into Neurons 4 ↓Neuron Activity 5 Anti-anxiety 6 Sedation 7 Anti-seizure 8
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  13 FLUOXETINE Class: SSRI(Selective Serotonin Reuptake Inhibitor) Use: Depression Action: Increases serotonin FLUOXETINE 1 Blocks Serotonin Reuptake 2 ↑Serotonin in Brain Synapses 3 Enhanced Serotonin Signaling 4 Brain Changes (Takes 2-4 weeks) 5 Mood Improvement 6
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  14 MORPHINE Class: Opioid Use:Severe pain Action: Blocks pain signals MORPHINE 1 Binds to μ-Opioid Receptors 2 Spinal Cord Action 3 Brain Action 4 ↓Pain Signal Transmission 5 ↓Pain Perception 6 PAIN RELIEF 7 Side Effects: Respiratory Depression Constipation 8
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  15 ASPIRIN Class: NSAID(Non-Steroidal Anti-Inflammatory Drug) Use: Pain, Fever, Antiplatelet Action: Blocks prostaglandin synthesis PharmFlow - Complete Pharmacology Flowcharts Collection PH 1.8: Demonstrate Mechanism of Drug Action using CAL Compiled by Dr. Shivankan Kakkar, MD ASPIRIN 1 Inhibits COX Enzymes 2 Blocks Prostaglandin Production 3 ↓PGE₂ 4 ↓TXA₂ 5 ↓PGI₂ 6 ↓Pain ↓Fever 7 ↓Platelet Clumping 8 ↓Inflammation 9