The PwC Health Research Institute's report predicts medical cost trends in 2021 could range from 4% to 10%, influenced by factors such as deferred care during the Covid-19 pandemic, increased mental health utilizations, and the growth of telehealth services. The report also indicates potential changes in employer-sponsored insurance and healthcare spending due to economic impacts from the pandemic. Key issues highlighted include the rising costs of specialty drugs and the ongoing need for effective communication between healthcare providers and patients amidst these changes.