MINIMALLY INVASIVE ENDODONTICS
V.NIVEDHA
CONTENTS:
 Introduction
 Preserving structural integrity
 Minimally invasive access strategies
 New concepts
 Shaping of root canal system
 Disinfection and its considerations
 Restoration strategies
CONTENTS:
 Is root strengthening a possibility
 Conclusion
 References
INTRODUCTION:
 Technological advances in optics, instrumentation, materials, robotics, and
computer systems over the last decades have introduced new strategies and
possibilities to the medical profession.
 These innovations are clearly beneficial to patients by dramatically improving
morbidity and mortality outcomes associated with many surgical procedures.
 Compared to medicine, such a shift to a non-invasive approach to surgery in
dentistry has been more moderate and cautious, perhaps with the exception of
endodontic and periodontal microsurgery
 The concept of minimally invasive endodontics calls for the treatment and
prevention of pulpal pathoses and apical periodontitis, while causing the least
amount of change to the dental hard tissues.
 This preserves the strength and function of the endodontically treated tooth with
the intent that it will last the patient’s lifetime.
 These skills include working with new instruments and irrigants for cleaning the
system; utilising advanced imaging modalities and computer software for
demonstrating both the complexities of the root canal system and improving the
accuracy of techniques;
 employing increased magnification and lighting for visualising the pulpal space as
well as applying new materials that enhance the prognosis for restoring structure
and retaining the natural dentition.
PRESERVING STRUCTURAL INTEGRITY
 It is apparent that remaining structural integrity of the tooth is a key factor that
determines prognosis as it relates to future function of the tooth after restoration
 Maintaining strength and stiffness that resists structural deformation becomes the
recognised goal of all restorative procedures, especially in endodontics.
 Appreciation for the biomechanical behaviour of dentin, as the limiting strength factor
of any restorative complex, requires the recognition that dentin is weakened unequally
by our restorative procedures
 The stiffness of cusps was assessed when comparing traditional cavity preparations
to endodontic access openings on bicuspid teeth.
 It was found that endodontic access openings by themselves have only a small (5%)
impact on tooth stiffness as opposed to any restorative preparation that removes the
tooth’s marginal ridges (for example, a MOD preparation) reducing cuspal stiffness
by 63%.
 The study identified approximately a 20% loss of tooth strength with each prepared
surface.
 These findings highlight that marginal ridges are a key factor in retaining tooth
strength.
 Another fundamental understanding of dentin behaviour within remaining structure
comes with the abandonment of the widely held clinical perception that
endodontically treated teeth are more brittle and hence more vulnerable to fracture.
 Conversely, the predominant reason that endodontically treated teeth are more
prone to fracture relates more than any other attribute to the structural loss of those
root treated teeth requiring restoration.
 Collectively, these studies show minimal dehydration effects from pulpal removal
and demonstrate biomechanical behaviours in strength and toughness testing that are
similar to vital dentin.
 Unfortunately, structural loss alone cannot answer every clinical question that
relates to dentin failure.
 The relevance of fatigue as a main mechanism for tooth fracture and the resistance
of dental tissues to both the initiation and propagation of cracks is an important
research area.
 Recently, investigations have focused on the impact of chemical factors such as
irrigants and medicaments on dentin; the effects of bacteria on the matrix of dentin;
structural loss; the effect of post and core restorations and the results of age changes
in dentin.
 Of note, there is a reduction of up to 50% in the tensile strength and fatigue strength
of coronal dentin in seniors (over 55 years) when compared to that of young adults.
 Similarly, the resistance to propagation of fatigue cracks in dentin decreases with
increasing patient age and the incremental rate of crack extension is up to 100 times
greater in seniors
BIOMECHANICAL BEHAVIOUR OF DENTIN
 When endodontically treated teeth fail under function, that outcome is determined
primarily by two aetiologies.
 Those causes stated most simply are: 1) the degree of stress experienced by the
tooth under load, and 2) the inherent biomechanical properties of the remaining
structure responsible for resisting fracture.
 It appears that, among technical elements of root canal therapy, access preparation
and post preparation are most relevant in rendering the tooth more susceptible to
significant destabilisation.
 Unfortunately, only a minimal number of long-term controlled clinical studies are
available to assess the relationship between restoration, especially with posts, tooth
fracture and the biomechanical behaviour of restored dentin
Minimally invasive endodontics
 The mechanical demands of human mastication create an endless number of
impacting variables and only those long-term clinical outcomes remain the gold
standard for evidence.
 Teeth that physically fail through a vertical or unrestorable root fracture do not have
to undergo endodontic treatment to experience this outcome.
 It has been demonstrated in the dental literature that all teeth, especially molars, can
fracture without any endodontic treatment, and while some state this is not a
common finding there are others who declare that the incidence is under-reported.
 However, when fracture occurs, it will inevitably have a devastating effect on both
the periodontal attachment and the bone adjacent to the fracture.
 Once a fracture begins in the root and continues it is characterised by involvement
of the root canal in the fracture progression;
 bacterial contamination of the failed section; food-debris, cements, necrotic tissue
and bacteria; as well as inflammation associated with a reactive periodontium.
 Studies involving Chinese populations have reported that fractures may occur
within teeth with vital pulps in individuals with excessive or repetitive oral chewing
habits.
 This is in agreement with Yeh who also suggested heavy masticatory forces as a
cause for root fracture.
 In addition, root fractures seem to be more prevalent in seniors and male
populations; pre-existing attrition is often a component of the condition.
MINIMALLY INVASIVE ACCESS STRATEGIES
 Root canal anatomy and the complexity of human pulpal systems provide
significant challenges for endodontic therapy.
 The first priority of effective therapy is to access, shape and clean the system in a
manner that will allow efficient and total filling of the root canal space, while
leaving the tooth with sufficient strength to function successfully.
 For almost a century endodontic textbooks have taught the student of dentistry to
expose the pulp chambers of teeth with ‘straight-line’ access to the orifice(s) of the
root canal.
 Access cavities were to be prepared and expanded so that their smallest dimensions
were dictated by the separation of the orifices on the pulpal floor and their widest
dimensions were at the occlusal.
 In this era of enhanced lighting and magnification, as well as highly flexible rotary
instruments, this approach to a doctrinaire access paradigm is being questioned as
perhaps overly invasive of the tooth and an approach that may condemn a tooth to
structural failure.
New concepts
TRUSS
ACCESS
NINJA ACCESS
X ENTRY
ACCESS
Dr.Buchanan
Soffit
a soffit, which is a small piece
of roof around the entire
coronal portion of the
pulp chamber
The idea that a round bur can be
dropped below this soffit and
drawn coronally to un roof the
chamber is predicated on large
pulp chambers and exceptional
hand skills. Clinically, it is
impossible
Attempting to remove the pulp
chamber roof does not
accomplish any real endodontic
objective, and invariably gouges
the walls that are responsible for
long-term survival of the tooth
The primary reason to maintain
the soffit is to avoid the collateral
damage that usually occurs,
namely the gouging of the
lateral walls.
 Recently, maintaining structural integrity of the peri-cervical area of the tooth
(about four mm above and below the alveolar crest) has been emphasised.
 Maintenance of the peri-cervical dentin (PCD), especially in molars is felt to be
critical to their long-term survivability and optimum function.
 Some argue that in treatment planning for endodontics, on a molar tooth
especially, clinicians must consider the significantly higher overall compressive
forces that create a situation requiring a different set of rules for the calculation of
ferrule, post and core design, resistance to fracturing, and most importantly,
endodontic access and removal of radicular dentin during endodontic sha,ping.
 In keeping with this philosophy of minimal invasion of bulk dentin structure, the use
of round burs and Gates-Glidden burs is now discouraged.
 While both of these types of instruments have been essential in endodontics for
decades, they are now recognised in endodontic treatment as instruments that
commonly gouge the endodontic access and the coronal third of the root canal , those
areas adjacent to the cemento-enamel junction (CEJ) of the tooth with critical
structural prerequisites.
 Gouging of the access and coronal canal space must be avoided in order to preserve
maximal resistance to structural flexure and ultimate failure.
 By directing the conservation of dentin and protecting dentin above and below the
PCD the practitioner ensures a more viable and proven method to reinforce the
endodontically treated tooth..
Minimally invasive endodontics
SHAPING OF ROOT CANAL SPACE
 Root canals are sometimes depicted as smooth hollow tubes that are more or less
tapered in shape.
 These misleading images do not reflect the intricate anatomical structure and
complexity of root canal systems.
 They are often asymmetrical or oval in cross section, they branch, dilacerate and
divide and the canal walls show concavities and convexities.
 Complex root canal anatomy should be considered one of the most significant
challenges in creating root canal shapes that will support good obturation outcomes
and
 leave sufficient remaining strength in the root. After biomechanical
instrumentation, the completed root canal shapes need to withstand the internal
compressive forces of obturation; provide sufficient resistance form to contain
softened and compressible filling materials and retain enough strength for
mastication
 Consequently, current shaping strategies employed by today’s clinicians align with
two general trends in contemporary endodontic practice.
 A significant number of practitioners believe that enhanced apical instrumentation
and larger apical diameters with minimal taper in the canal shape leads to
weakening of the root structure and a loss.
 They advocate smaller apical preparations, continuous taper, and a preparation that
promotes resistance form, a tight apical seal and a conservative approach to
creating sufficient shape for adequate disinfection
Minimally invasive endodontics
 Smaller apical sizes preserve dentin.
 The arguments are strategic and technique-driven, albeit often supported by inferred
outcomes.
 The impetus for smaller apical sizes has been directed at the disinfection and
obturation phase of endodontic therapy.
 On the other hand, there is a significant body of literature that presents evidence
that larger apical canal diameters are important to shape the apical canal wall, flush
debris, allow deeper irrigation to the terminus and decrease remaining bacterial
contamination in the system
Minimally invasive endodontics
 Some researchers have suggested file diameters ranging from #35-#45 to accomplish
significant bacterial reduction.
 Others have shown that minimal sizes can accomplish this task as adequately as
larger diameters.
 What is remarkably clear from the evidence is that no matter which school of thought
one ascribes to, it is not possible that any apical preparation technique will render the
terminus entirely free of bacterial contamination in an infected canal.
 In essence, structural considerations in shaping continue to remain a compelling
argument for conservative shapes.
 Weine et al. and others have described and elucidated the structural damage and
preparation errors that can occur while shaping root canals with stainless steel
instruments to large sizes.
 Transportation, ledging, apical perforation and loss of the original canal position are
all well recognised shaping errors that often lead to loss of working length, ledging
and damage to the apical terminus leading to weakening of the root structure at its
most fragile levels.
 There is now a large body of conclusive research quantifying the use of rotary and
hand nickel-titanium instruments first described by Walia who report that the use of
this super-elastic metal alloy offers less straightening and better centered preparations
compared to traditional stainless steel instruments in preparing the wide range of
anatomical variability seen in teeth.
 These studies have focused on the geometry of shape produced by these instruments
alone or in combination with stainless steel; including conicity, taper, flow and
maintenance of original canal position.
 Most of these studies have recorded the degree of change from original position and
have measured the loss of original canal positions based on the definitions by Weine.
 In comparing stainless steel versus nickel-titanium, researchers have focused on both
the metallurgy of the systems and the systems themselves.
 Collectively these studies suggest that Nickel-titanium technology alone or in
combination with the conservative use of stainless steel instruments provides shapes
that are better centered, maintaining the original canal positions with greater
conservation of dentin and safer radicular preparations.
DISINFECTION AND OTHER CONSIDERATIONS
IN MINIMALLY INVASIVE ENDODONTICS
 In order to address the microbiologic aetiology of endodontic disease, that is,
periapical inflammation, disinfection is and will always remain, a key element of
the overall treatment strategy.
 At first glance, any minimally invasive approach to root canal treatment is at
conflict with disinfection.
 Microbiological studies in vitro, however, do not provide a definitive answer as to
the required preparation size for antimicrobial efficacy
Minimally invasive endodontics
 More recently a clinical study rekindled the notion of a preparation ‘three sizes larger
than the initial size’;
 however, a large clinical data set does not support any particular canal shape as being
associated with apical healing or retention of a root canal-treated tooth.
 Current cleaning and shaping methods appear to be unlikely to predictably remove all
bio-burden from the root canal system.
 Therefore, and particularly under the conditions of smaller apical preparation sizes,
the search continues for techniques to enhance irrigation efficacy.
 The possibilities for physical means that enable enhanced disinfection vary from
ultrasonic or sonic activation up to and including laser activation
 The effect of a modified access cavity design has only recently been tested in
extracted teeth.
 Using a combined micro-computed tomography and load-to-failure approach,
Krishan et al.found that in premolars shaping was not impacted and load to failure
was significantly higher for teeth with minimal access cavity designs.
 While the idea of minimally invasive endodontics has been promoted recently, there
is a scarcity of independent evaluations for such a strategy.
 For example, root canal preparation instruments sometimes associated with this
strategy such as V-Taper (SS White, Lakewood, NJ, USA) and Endo-EZE AET
(Ultradent, South Jordan UT, USA) have not been shown to actually perform in a
superior way to traditional rotary instrumentation in the laboratory.
 Another aspect of this discussion is the finding of micro-cracks induced by various
rotary shaping procedures in canal preparation..
 In recent years several investigations have illustrated such micro-cracks in extracted
teeth.
 While it is not clear at this point if such cracks are generated in vivo, it may be
reasonable to develop instruments that reduce vibration and rotational stresses
during intracanal procedures in an effort to lessen additional loads on a structurally
weakened root
 Micro-computed tomography studies not only show overall canal shaping outcomes
but have also demonstrated that hard tissue debris is compacted into unshaped canal
areas rendering them potentially inaccessible to irrigation.
 It is likely future root canal preparation techniques will have to focus on balancing
disinfection capacity and iatrogenic damage with enhanced debridement and
disinfection.
RESTORATION STRATEGIES FOR MAXIMUM
PROTECTION AND MINIMAL INVASION
 In extensive reviews of evidence surrounding the restoration of endodontically treated
teeth, preserving intact coronal and radicular tooth structure, especially maintaining
the peri-cervical structure to allow a substantial ‘ferrule effect’, is considered to be
crucial for the optimal biomechanical behaviour of restored teeth.
 Encircling the parallel walls of remaining dentin with the crown margin allows a
ferrule that provides a protective effect by reducing stresses within a tooth.
 The presence of a 1.5 to 2 mm ferrule has a positive effect on fracture resistance of
endodontically treated teeth.
 Teeth with a ferrule of one mm of vertical tooth structure doubled the resistance to
fracture compared with teeth restored without a ferrule.
 Even if the clinical situation does not permit a circumferential ferrule, an
incomplete ferrule is considered a better option than a complete lack of ferrule.
 However, it can be generally concluded that providing an adequate ferrule lessens
the destabilising impact of the post and core system and the final restoration in the
long-term performance of restored root treated teeth.
 When it comes to severely damaged teeth with little or no coronal structure, in
order to provide space for a ferrule, orthodontic extrusion should be considered
rather than surgical crown lengthening.
 This approach preserves more tooth structure and ensures a more favourable
biomechanical behaviour of remaining dentin structure.
 If neither of the alternative methods for providing a ferrule for the restoration can
be performed, currently available evidence suggests that a poor treatment outcome
and the ultimate the loss of the tooth has a high probability.
IS ROOT STRENGTHENING A POSSIBILITY
 The past decade has seen a considerable change in clinical strategies for using and
placing posts.
 An advancing principle promoting minimally invasive therapy directs the nominal
use of posts in endodontically treated teeth.
 That principle, based on evidence, affirms that retaining tooth structure is more
valuable than the use of a post in almost every circumstance where adequate
structure exists for a ferrule.
 The long-term success of endodontic treatment has always been highly dependent
on the restorative treatment that follows. A restored tooth must be structurally
sound and the sealed state of the root canal system must be maintained.
 Most endodontically treated teeth today are restored with adhesive materials.
 Adhesive bonding provides an immediate seal of the pulpal spaces and some
immediate toughening of the tooth.
 These materials are generally not dependent on gross mechanical retention, so tooth
structure can be preserved and these materials can certainly be termed minimally
invasive
Minimally invasive endodontics
DIDIERDIETSCHICLASSIFICATION
Minimally invasive endodontics
 Conventional thought has been that posts do not ‘reinforce’ the root. Early
restorative protocols considered this true for metal posts, but there is now a growing
body of evidence that bonded fibre posts can be placed with no removal of dentin
structure, may protect the root and make it more resistant to fracture.
 Fibre-reinforced resin posts were introduced over 20 years ago with the intent to
provide more elastic support to the core.
 The reduced stress transfer to tooth structure lowered the likelihood of root
fracture. In addition, posts made of materials with a modulus of elasticity similar to
dentin were considered more resilient; able to absorb similar impact forces, and
distribute the forces of mastication in a more protective manner to remaining dentin
than stiffer metallic posts.
 Based on the aforementioned evidence, it may be premature to describe adhesive
technology as ‘reinforcing’ or ‘root strengthening’ but in terms of distributing forces
throughout the remaining dentin structure it may certainly be deemed ‘protective’.
 To resolve apical periodontitis and more advanced pulpal disease, the conventional
treatment is removal of the complete pulp (root canal treatment) with the aim to
reduce the number of bacteria in the rootcanal system which cause infection.
 However, crosssectional research in the Netherlands has shown that around forty
per cent of root filled teeth are associated with an apical radiolucency when
examined using two-dimensional dental radiographs (Peters et al. 2011), indicating
failure of the procedure, as only a small proportion of apical radiolucencies remain
visible as fibrotic healing scars (Nair et al. 1999, Love & Firth 2009).
 This trend is seen worldwide (Wu et al. 2009). Furthermore, endodontically treated
teeth without visible radiographic signs of apical periodontitis can still be infected
(Molander et al. 1998, Ricucci et al. 2014).
 Therefore, the actual failure rate of standard root canal treatments performed in
general practice is significantly higher than expected.
 Furthermore, these treatments are lengthy and costly and are often subject to
retreatment (Figdor 2002).
 Less invasive alternative strategies could be used to treat pulpitis and increase the
success of endodontic procedures beyond the improvement of the ‘tools and gadgets’
used during conventional root canal treatment.
 Such treatment modalities have two major advantages: first, pulp tissue is preserved,
thus maintaining its physiological and defensive functions; secondly, less hard tooth
tissue is removed, which results in less weakening of the tooth.
 This less invasive treatment approach (‘Endolight’) has the following advantages:
1. preservation of immunological functions and retaining structural integrity of the
tooth.
2. simplifying treatment procedures and avoiding treatment complication associated
with difficult root canal anatomy.
3. suggested procedures cause little pain (Simon et al. 2013).
4. reducing cost and inconvenience for patients and society.
 Using vital pulp therapy, proper case selection and treatment protocols are essential
if it is to be successful (Taha et al. 2017).
 Teeth exhibiting symptoms suggestive of irreversible pulpitis have little chance to
revert to normal if no other intervention takes place than removal of irritants.
 In these cases, the section of the pulp that is inflamed must be removed so that the
remaining uninflamed tissue can recover and heal (Ricucci et al. 2014).
 This has proven to be successful, and teeth diagnosed with irreversible pulpitis have
been successfully treated with a pulpotomy (Taha et al. 2017,
 INITIAL PULPITIS
 Heightened but not lengthened response to the cold test, not sensitive to percussion
and no spontaneous pain. Therapy: IPT (van der Sluis et al. 2013, Asgaryet al. 2015)
 MILD PULPITIS
 Heightened and lengthened reaction to cold, warmth and sweet stimuli that can last
up to 20 s but then subsides, possibly percussion sensitive. According to the
histological situation that fits these findings, it would be implied that there is limited
local inflammation confined to the crown pulp.
 MODERATE PULPITIS
 Clear symptoms, strong, heightened and prolonged reaction to cold, which can last
for minutes, possibly percussion sensitive and spontaneous dull pain that can be more
or less suppressed with pain medication. According to the histological situation that
fits these findings, it would be implied that there is extensive local inflammation
confined to the crown pulp. Therapy: Coronal pulpotomy – partly/completely
 SEVERE PULPITIS
 Severe spontaneous pain and clear pain reaction to warmth and cold stimuli, often,
sharp to dull throbbing pain, patients have trouble sleeping because of the pain
(gets worse when lying down).
 Tooth is very sensitive to touch and percussion. According to the histological
situation that fits these findings, it would be implied that there is extensive local
inflammation in the crown pulp that possibly extends into the root canals.
 Therapy: Coronal pulpotomy – if there is no prolonged bleeding of pulp stumps in
the orifices of the canals, these will be covered with MTA in mature teeth, followed
by restoration (Alqaderi et al. 2014).
 If one or more of the pulp stumps keeps bleeding after rinsing with 2 mL 2%
NaOCl, a superficial pulpotomy can be carried out, whereby more inflamed tissue
is removed from the canal up to 3–4 mm from the radiographic apex.
 If bleeding ceases, then the root canal up to the vital pulp tissue is filled with
guttapercha and sealer at this working length.
 If bleeding persists, a full pulpectomy needs to be performed in order to remove all
inflamed tissue from the canal (Matsuo et al. 1996).
Conclusion:
 The causes for post-treatment loss of teeth after endodontic therapy, when the
therapy itself has been successful, have been described in this article by citing
many diverse authorities. The loss of a tooth after successful endodontic therapy
can invariably be attributed to one or more predictable explanations. Often these
sequelae are clinically avoidable and the result of an approach to therapy that is far
more invasive than required to remove and cure the causes of apical periodontitis.
These outcomes include:
• Poor access cavity design and execution
• An iatrogenic or procedural mishap weakening peri-cervical integrity
• Instrumentation errors such a ledging, perforation, transportation from centre
• Coronal leakage and recontamination of the pulpal space
• Crown and root fracture.
 As practitioners of the art and science of dentistry, poor outcomes in the course of
endodontic treatment should encourage reflection on the careful and prudent
practice of endodontics that safeguards against undesired consequences.
 Our obligation as experts is to protect patients from iatrogenic harm.
 This responsibility is met when we as a profession can provide advanced and
sophisticated therapies in a safe and controlled manner with preservation of the
dentition as an overriding priority in all aspects of our treatments
References:
 Minimally invasive endodontics: Challenging prevailing paradigms Article in
British dental journal official journal of the British Dental Association: BDJ
online · March 2014
 Minimally Invasive Endodontics a Promising Future Concept: A Review
Article Prithwish Mukherjee1, Aditya Patel2, M Chandak3, Rasika Kashikar
International Journal of Scientific Study | April 2017 | Vol 5 | Issue 1
 Minimally invasive endodontics: a new diagnostic system for assessing pulpitis and
subsequent treatment needs W. J. Wolters1, H. F. Duncan2, P. L. Tomson3, I. E.
Karim4, G. McKenna5, M. Dorri6, L. Stangvaltaite7 & L. W. M. van der Sluis1
International Endodontic Journal, 50, 825–829, 2017
 Cohen
 Ingle

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Impression materials and gingival tissue management
Bonding to enamel and dentin
Dental Casting alloys
Root resorption
Obturation of root canal system
Endodontic emergencies
Dentin
Endodontic mishaps/PROCEDURAL ACCIDENTS

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Minimally invasive endodontics

  • 2. CONTENTS:  Introduction  Preserving structural integrity  Minimally invasive access strategies  New concepts  Shaping of root canal system  Disinfection and its considerations  Restoration strategies
  • 3. CONTENTS:  Is root strengthening a possibility  Conclusion  References
  • 4. INTRODUCTION:  Technological advances in optics, instrumentation, materials, robotics, and computer systems over the last decades have introduced new strategies and possibilities to the medical profession.  These innovations are clearly beneficial to patients by dramatically improving morbidity and mortality outcomes associated with many surgical procedures.  Compared to medicine, such a shift to a non-invasive approach to surgery in dentistry has been more moderate and cautious, perhaps with the exception of endodontic and periodontal microsurgery
  • 5.  The concept of minimally invasive endodontics calls for the treatment and prevention of pulpal pathoses and apical periodontitis, while causing the least amount of change to the dental hard tissues.  This preserves the strength and function of the endodontically treated tooth with the intent that it will last the patient’s lifetime.  These skills include working with new instruments and irrigants for cleaning the system; utilising advanced imaging modalities and computer software for demonstrating both the complexities of the root canal system and improving the accuracy of techniques;  employing increased magnification and lighting for visualising the pulpal space as well as applying new materials that enhance the prognosis for restoring structure and retaining the natural dentition.
  • 6. PRESERVING STRUCTURAL INTEGRITY  It is apparent that remaining structural integrity of the tooth is a key factor that determines prognosis as it relates to future function of the tooth after restoration  Maintaining strength and stiffness that resists structural deformation becomes the recognised goal of all restorative procedures, especially in endodontics.  Appreciation for the biomechanical behaviour of dentin, as the limiting strength factor of any restorative complex, requires the recognition that dentin is weakened unequally by our restorative procedures
  • 7.  The stiffness of cusps was assessed when comparing traditional cavity preparations to endodontic access openings on bicuspid teeth.  It was found that endodontic access openings by themselves have only a small (5%) impact on tooth stiffness as opposed to any restorative preparation that removes the tooth’s marginal ridges (for example, a MOD preparation) reducing cuspal stiffness by 63%.  The study identified approximately a 20% loss of tooth strength with each prepared surface.  These findings highlight that marginal ridges are a key factor in retaining tooth strength.
  • 8.  Another fundamental understanding of dentin behaviour within remaining structure comes with the abandonment of the widely held clinical perception that endodontically treated teeth are more brittle and hence more vulnerable to fracture.  Conversely, the predominant reason that endodontically treated teeth are more prone to fracture relates more than any other attribute to the structural loss of those root treated teeth requiring restoration.  Collectively, these studies show minimal dehydration effects from pulpal removal and demonstrate biomechanical behaviours in strength and toughness testing that are similar to vital dentin.  Unfortunately, structural loss alone cannot answer every clinical question that relates to dentin failure.
  • 9.  The relevance of fatigue as a main mechanism for tooth fracture and the resistance of dental tissues to both the initiation and propagation of cracks is an important research area.  Recently, investigations have focused on the impact of chemical factors such as irrigants and medicaments on dentin; the effects of bacteria on the matrix of dentin; structural loss; the effect of post and core restorations and the results of age changes in dentin.  Of note, there is a reduction of up to 50% in the tensile strength and fatigue strength of coronal dentin in seniors (over 55 years) when compared to that of young adults.  Similarly, the resistance to propagation of fatigue cracks in dentin decreases with increasing patient age and the incremental rate of crack extension is up to 100 times greater in seniors
  • 10. BIOMECHANICAL BEHAVIOUR OF DENTIN  When endodontically treated teeth fail under function, that outcome is determined primarily by two aetiologies.  Those causes stated most simply are: 1) the degree of stress experienced by the tooth under load, and 2) the inherent biomechanical properties of the remaining structure responsible for resisting fracture.  It appears that, among technical elements of root canal therapy, access preparation and post preparation are most relevant in rendering the tooth more susceptible to significant destabilisation.  Unfortunately, only a minimal number of long-term controlled clinical studies are available to assess the relationship between restoration, especially with posts, tooth fracture and the biomechanical behaviour of restored dentin
  • 12.  The mechanical demands of human mastication create an endless number of impacting variables and only those long-term clinical outcomes remain the gold standard for evidence.  Teeth that physically fail through a vertical or unrestorable root fracture do not have to undergo endodontic treatment to experience this outcome.  It has been demonstrated in the dental literature that all teeth, especially molars, can fracture without any endodontic treatment, and while some state this is not a common finding there are others who declare that the incidence is under-reported.  However, when fracture occurs, it will inevitably have a devastating effect on both the periodontal attachment and the bone adjacent to the fracture.
  • 13.  Once a fracture begins in the root and continues it is characterised by involvement of the root canal in the fracture progression;  bacterial contamination of the failed section; food-debris, cements, necrotic tissue and bacteria; as well as inflammation associated with a reactive periodontium.  Studies involving Chinese populations have reported that fractures may occur within teeth with vital pulps in individuals with excessive or repetitive oral chewing habits.  This is in agreement with Yeh who also suggested heavy masticatory forces as a cause for root fracture.  In addition, root fractures seem to be more prevalent in seniors and male populations; pre-existing attrition is often a component of the condition.
  • 14. MINIMALLY INVASIVE ACCESS STRATEGIES  Root canal anatomy and the complexity of human pulpal systems provide significant challenges for endodontic therapy.  The first priority of effective therapy is to access, shape and clean the system in a manner that will allow efficient and total filling of the root canal space, while leaving the tooth with sufficient strength to function successfully.  For almost a century endodontic textbooks have taught the student of dentistry to expose the pulp chambers of teeth with ‘straight-line’ access to the orifice(s) of the root canal.
  • 15.  Access cavities were to be prepared and expanded so that their smallest dimensions were dictated by the separation of the orifices on the pulpal floor and their widest dimensions were at the occlusal.  In this era of enhanced lighting and magnification, as well as highly flexible rotary instruments, this approach to a doctrinaire access paradigm is being questioned as perhaps overly invasive of the tooth and an approach that may condemn a tooth to structural failure.
  • 16. New concepts TRUSS ACCESS NINJA ACCESS X ENTRY ACCESS Dr.Buchanan
  • 17. Soffit a soffit, which is a small piece of roof around the entire coronal portion of the pulp chamber The idea that a round bur can be dropped below this soffit and drawn coronally to un roof the chamber is predicated on large pulp chambers and exceptional hand skills. Clinically, it is impossible Attempting to remove the pulp chamber roof does not accomplish any real endodontic objective, and invariably gouges the walls that are responsible for long-term survival of the tooth The primary reason to maintain the soffit is to avoid the collateral damage that usually occurs, namely the gouging of the lateral walls.
  • 18.  Recently, maintaining structural integrity of the peri-cervical area of the tooth (about four mm above and below the alveolar crest) has been emphasised.  Maintenance of the peri-cervical dentin (PCD), especially in molars is felt to be critical to their long-term survivability and optimum function.  Some argue that in treatment planning for endodontics, on a molar tooth especially, clinicians must consider the significantly higher overall compressive forces that create a situation requiring a different set of rules for the calculation of ferrule, post and core design, resistance to fracturing, and most importantly, endodontic access and removal of radicular dentin during endodontic sha,ping.
  • 19.  In keeping with this philosophy of minimal invasion of bulk dentin structure, the use of round burs and Gates-Glidden burs is now discouraged.  While both of these types of instruments have been essential in endodontics for decades, they are now recognised in endodontic treatment as instruments that commonly gouge the endodontic access and the coronal third of the root canal , those areas adjacent to the cemento-enamel junction (CEJ) of the tooth with critical structural prerequisites.  Gouging of the access and coronal canal space must be avoided in order to preserve maximal resistance to structural flexure and ultimate failure.  By directing the conservation of dentin and protecting dentin above and below the PCD the practitioner ensures a more viable and proven method to reinforce the endodontically treated tooth..
  • 21. SHAPING OF ROOT CANAL SPACE  Root canals are sometimes depicted as smooth hollow tubes that are more or less tapered in shape.  These misleading images do not reflect the intricate anatomical structure and complexity of root canal systems.  They are often asymmetrical or oval in cross section, they branch, dilacerate and divide and the canal walls show concavities and convexities.  Complex root canal anatomy should be considered one of the most significant challenges in creating root canal shapes that will support good obturation outcomes and
  • 22.  leave sufficient remaining strength in the root. After biomechanical instrumentation, the completed root canal shapes need to withstand the internal compressive forces of obturation; provide sufficient resistance form to contain softened and compressible filling materials and retain enough strength for mastication
  • 23.  Consequently, current shaping strategies employed by today’s clinicians align with two general trends in contemporary endodontic practice.  A significant number of practitioners believe that enhanced apical instrumentation and larger apical diameters with minimal taper in the canal shape leads to weakening of the root structure and a loss.  They advocate smaller apical preparations, continuous taper, and a preparation that promotes resistance form, a tight apical seal and a conservative approach to creating sufficient shape for adequate disinfection
  • 25.  Smaller apical sizes preserve dentin.  The arguments are strategic and technique-driven, albeit often supported by inferred outcomes.  The impetus for smaller apical sizes has been directed at the disinfection and obturation phase of endodontic therapy.  On the other hand, there is a significant body of literature that presents evidence that larger apical canal diameters are important to shape the apical canal wall, flush debris, allow deeper irrigation to the terminus and decrease remaining bacterial contamination in the system
  • 27.  Some researchers have suggested file diameters ranging from #35-#45 to accomplish significant bacterial reduction.  Others have shown that minimal sizes can accomplish this task as adequately as larger diameters.  What is remarkably clear from the evidence is that no matter which school of thought one ascribes to, it is not possible that any apical preparation technique will render the terminus entirely free of bacterial contamination in an infected canal.  In essence, structural considerations in shaping continue to remain a compelling argument for conservative shapes.
  • 28.  Weine et al. and others have described and elucidated the structural damage and preparation errors that can occur while shaping root canals with stainless steel instruments to large sizes.  Transportation, ledging, apical perforation and loss of the original canal position are all well recognised shaping errors that often lead to loss of working length, ledging and damage to the apical terminus leading to weakening of the root structure at its most fragile levels.  There is now a large body of conclusive research quantifying the use of rotary and hand nickel-titanium instruments first described by Walia who report that the use of this super-elastic metal alloy offers less straightening and better centered preparations compared to traditional stainless steel instruments in preparing the wide range of anatomical variability seen in teeth.
  • 29.  These studies have focused on the geometry of shape produced by these instruments alone or in combination with stainless steel; including conicity, taper, flow and maintenance of original canal position.  Most of these studies have recorded the degree of change from original position and have measured the loss of original canal positions based on the definitions by Weine.  In comparing stainless steel versus nickel-titanium, researchers have focused on both the metallurgy of the systems and the systems themselves.  Collectively these studies suggest that Nickel-titanium technology alone or in combination with the conservative use of stainless steel instruments provides shapes that are better centered, maintaining the original canal positions with greater conservation of dentin and safer radicular preparations.
  • 30. DISINFECTION AND OTHER CONSIDERATIONS IN MINIMALLY INVASIVE ENDODONTICS  In order to address the microbiologic aetiology of endodontic disease, that is, periapical inflammation, disinfection is and will always remain, a key element of the overall treatment strategy.  At first glance, any minimally invasive approach to root canal treatment is at conflict with disinfection.  Microbiological studies in vitro, however, do not provide a definitive answer as to the required preparation size for antimicrobial efficacy
  • 32.  More recently a clinical study rekindled the notion of a preparation ‘three sizes larger than the initial size’;  however, a large clinical data set does not support any particular canal shape as being associated with apical healing or retention of a root canal-treated tooth.  Current cleaning and shaping methods appear to be unlikely to predictably remove all bio-burden from the root canal system.  Therefore, and particularly under the conditions of smaller apical preparation sizes, the search continues for techniques to enhance irrigation efficacy.  The possibilities for physical means that enable enhanced disinfection vary from ultrasonic or sonic activation up to and including laser activation
  • 33.  The effect of a modified access cavity design has only recently been tested in extracted teeth.  Using a combined micro-computed tomography and load-to-failure approach, Krishan et al.found that in premolars shaping was not impacted and load to failure was significantly higher for teeth with minimal access cavity designs.  While the idea of minimally invasive endodontics has been promoted recently, there is a scarcity of independent evaluations for such a strategy.  For example, root canal preparation instruments sometimes associated with this strategy such as V-Taper (SS White, Lakewood, NJ, USA) and Endo-EZE AET (Ultradent, South Jordan UT, USA) have not been shown to actually perform in a superior way to traditional rotary instrumentation in the laboratory.  Another aspect of this discussion is the finding of micro-cracks induced by various rotary shaping procedures in canal preparation..
  • 34.  In recent years several investigations have illustrated such micro-cracks in extracted teeth.  While it is not clear at this point if such cracks are generated in vivo, it may be reasonable to develop instruments that reduce vibration and rotational stresses during intracanal procedures in an effort to lessen additional loads on a structurally weakened root  Micro-computed tomography studies not only show overall canal shaping outcomes but have also demonstrated that hard tissue debris is compacted into unshaped canal areas rendering them potentially inaccessible to irrigation.  It is likely future root canal preparation techniques will have to focus on balancing disinfection capacity and iatrogenic damage with enhanced debridement and disinfection.
  • 35. RESTORATION STRATEGIES FOR MAXIMUM PROTECTION AND MINIMAL INVASION  In extensive reviews of evidence surrounding the restoration of endodontically treated teeth, preserving intact coronal and radicular tooth structure, especially maintaining the peri-cervical structure to allow a substantial ‘ferrule effect’, is considered to be crucial for the optimal biomechanical behaviour of restored teeth.  Encircling the parallel walls of remaining dentin with the crown margin allows a ferrule that provides a protective effect by reducing stresses within a tooth.  The presence of a 1.5 to 2 mm ferrule has a positive effect on fracture resistance of endodontically treated teeth.  Teeth with a ferrule of one mm of vertical tooth structure doubled the resistance to fracture compared with teeth restored without a ferrule.
  • 36.  Even if the clinical situation does not permit a circumferential ferrule, an incomplete ferrule is considered a better option than a complete lack of ferrule.  However, it can be generally concluded that providing an adequate ferrule lessens the destabilising impact of the post and core system and the final restoration in the long-term performance of restored root treated teeth.  When it comes to severely damaged teeth with little or no coronal structure, in order to provide space for a ferrule, orthodontic extrusion should be considered rather than surgical crown lengthening.  This approach preserves more tooth structure and ensures a more favourable biomechanical behaviour of remaining dentin structure.  If neither of the alternative methods for providing a ferrule for the restoration can be performed, currently available evidence suggests that a poor treatment outcome and the ultimate the loss of the tooth has a high probability.
  • 37. IS ROOT STRENGTHENING A POSSIBILITY  The past decade has seen a considerable change in clinical strategies for using and placing posts.  An advancing principle promoting minimally invasive therapy directs the nominal use of posts in endodontically treated teeth.  That principle, based on evidence, affirms that retaining tooth structure is more valuable than the use of a post in almost every circumstance where adequate structure exists for a ferrule.  The long-term success of endodontic treatment has always been highly dependent on the restorative treatment that follows. A restored tooth must be structurally sound and the sealed state of the root canal system must be maintained.
  • 38.  Most endodontically treated teeth today are restored with adhesive materials.  Adhesive bonding provides an immediate seal of the pulpal spaces and some immediate toughening of the tooth.  These materials are generally not dependent on gross mechanical retention, so tooth structure can be preserved and these materials can certainly be termed minimally invasive
  • 42.  Conventional thought has been that posts do not ‘reinforce’ the root. Early restorative protocols considered this true for metal posts, but there is now a growing body of evidence that bonded fibre posts can be placed with no removal of dentin structure, may protect the root and make it more resistant to fracture.  Fibre-reinforced resin posts were introduced over 20 years ago with the intent to provide more elastic support to the core.  The reduced stress transfer to tooth structure lowered the likelihood of root fracture. In addition, posts made of materials with a modulus of elasticity similar to dentin were considered more resilient; able to absorb similar impact forces, and distribute the forces of mastication in a more protective manner to remaining dentin than stiffer metallic posts.  Based on the aforementioned evidence, it may be premature to describe adhesive technology as ‘reinforcing’ or ‘root strengthening’ but in terms of distributing forces throughout the remaining dentin structure it may certainly be deemed ‘protective’.
  • 43.  To resolve apical periodontitis and more advanced pulpal disease, the conventional treatment is removal of the complete pulp (root canal treatment) with the aim to reduce the number of bacteria in the rootcanal system which cause infection.  However, crosssectional research in the Netherlands has shown that around forty per cent of root filled teeth are associated with an apical radiolucency when examined using two-dimensional dental radiographs (Peters et al. 2011), indicating failure of the procedure, as only a small proportion of apical radiolucencies remain visible as fibrotic healing scars (Nair et al. 1999, Love & Firth 2009).
  • 44.  This trend is seen worldwide (Wu et al. 2009). Furthermore, endodontically treated teeth without visible radiographic signs of apical periodontitis can still be infected (Molander et al. 1998, Ricucci et al. 2014).  Therefore, the actual failure rate of standard root canal treatments performed in general practice is significantly higher than expected.  Furthermore, these treatments are lengthy and costly and are often subject to retreatment (Figdor 2002).  Less invasive alternative strategies could be used to treat pulpitis and increase the success of endodontic procedures beyond the improvement of the ‘tools and gadgets’ used during conventional root canal treatment.  Such treatment modalities have two major advantages: first, pulp tissue is preserved, thus maintaining its physiological and defensive functions; secondly, less hard tooth tissue is removed, which results in less weakening of the tooth.
  • 45.  This less invasive treatment approach (‘Endolight’) has the following advantages: 1. preservation of immunological functions and retaining structural integrity of the tooth. 2. simplifying treatment procedures and avoiding treatment complication associated with difficult root canal anatomy. 3. suggested procedures cause little pain (Simon et al. 2013). 4. reducing cost and inconvenience for patients and society.
  • 46.  Using vital pulp therapy, proper case selection and treatment protocols are essential if it is to be successful (Taha et al. 2017).  Teeth exhibiting symptoms suggestive of irreversible pulpitis have little chance to revert to normal if no other intervention takes place than removal of irritants.  In these cases, the section of the pulp that is inflamed must be removed so that the remaining uninflamed tissue can recover and heal (Ricucci et al. 2014).  This has proven to be successful, and teeth diagnosed with irreversible pulpitis have been successfully treated with a pulpotomy (Taha et al. 2017,
  • 47.  INITIAL PULPITIS  Heightened but not lengthened response to the cold test, not sensitive to percussion and no spontaneous pain. Therapy: IPT (van der Sluis et al. 2013, Asgaryet al. 2015)  MILD PULPITIS  Heightened and lengthened reaction to cold, warmth and sweet stimuli that can last up to 20 s but then subsides, possibly percussion sensitive. According to the histological situation that fits these findings, it would be implied that there is limited local inflammation confined to the crown pulp.  MODERATE PULPITIS  Clear symptoms, strong, heightened and prolonged reaction to cold, which can last for minutes, possibly percussion sensitive and spontaneous dull pain that can be more or less suppressed with pain medication. According to the histological situation that fits these findings, it would be implied that there is extensive local inflammation confined to the crown pulp. Therapy: Coronal pulpotomy – partly/completely
  • 48.  SEVERE PULPITIS  Severe spontaneous pain and clear pain reaction to warmth and cold stimuli, often, sharp to dull throbbing pain, patients have trouble sleeping because of the pain (gets worse when lying down).  Tooth is very sensitive to touch and percussion. According to the histological situation that fits these findings, it would be implied that there is extensive local inflammation in the crown pulp that possibly extends into the root canals.  Therapy: Coronal pulpotomy – if there is no prolonged bleeding of pulp stumps in the orifices of the canals, these will be covered with MTA in mature teeth, followed by restoration (Alqaderi et al. 2014).
  • 49.  If one or more of the pulp stumps keeps bleeding after rinsing with 2 mL 2% NaOCl, a superficial pulpotomy can be carried out, whereby more inflamed tissue is removed from the canal up to 3–4 mm from the radiographic apex.  If bleeding ceases, then the root canal up to the vital pulp tissue is filled with guttapercha and sealer at this working length.  If bleeding persists, a full pulpectomy needs to be performed in order to remove all inflamed tissue from the canal (Matsuo et al. 1996).
  • 50. Conclusion:  The causes for post-treatment loss of teeth after endodontic therapy, when the therapy itself has been successful, have been described in this article by citing many diverse authorities. The loss of a tooth after successful endodontic therapy can invariably be attributed to one or more predictable explanations. Often these sequelae are clinically avoidable and the result of an approach to therapy that is far more invasive than required to remove and cure the causes of apical periodontitis. These outcomes include: • Poor access cavity design and execution • An iatrogenic or procedural mishap weakening peri-cervical integrity • Instrumentation errors such a ledging, perforation, transportation from centre • Coronal leakage and recontamination of the pulpal space • Crown and root fracture.
  • 51.  As practitioners of the art and science of dentistry, poor outcomes in the course of endodontic treatment should encourage reflection on the careful and prudent practice of endodontics that safeguards against undesired consequences.  Our obligation as experts is to protect patients from iatrogenic harm.  This responsibility is met when we as a profession can provide advanced and sophisticated therapies in a safe and controlled manner with preservation of the dentition as an overriding priority in all aspects of our treatments
  • 52. References:  Minimally invasive endodontics: Challenging prevailing paradigms Article in British dental journal official journal of the British Dental Association: BDJ online · March 2014  Minimally Invasive Endodontics a Promising Future Concept: A Review Article Prithwish Mukherjee1, Aditya Patel2, M Chandak3, Rasika Kashikar International Journal of Scientific Study | April 2017 | Vol 5 | Issue 1  Minimally invasive endodontics: a new diagnostic system for assessing pulpitis and subsequent treatment needs W. J. Wolters1, H. F. Duncan2, P. L. Tomson3, I. E. Karim4, G. McKenna5, M. Dorri6, L. Stangvaltaite7 & L. W. M. van der Sluis1 International Endodontic Journal, 50, 825–829, 2017