Missing Facts of  Evidence Based Medicine
Thomas Kuhn Structure of Scientific Revolution 1962 Paradigm
“ If it is spoken loudly with greater confidence and charisma” Truth
A statement is a generator of prediction  It is true if it generates only true predictions. Truth in Science
Evidence is a piece of information that supports a conclusion What is Evidence?
Past Event (Law) Future Event – Prediction (Medicine) Types of Evidence
Source of Evidence Subjective Objective
For science, what is real is only what can be counted or measured.  Anything that is not visible is "unscientific" and therefore does not exist.  Physical reality is the only reality.  Objective Evidence
Evolution of Objective Brain
Mathematics has become the language of science We started translating all natural phenomenon to Mathematics  Any phenomenon  can be presented in mathematical is taken as truth Maths and science
Statistical Evidence Statistics has become prime source of  explanation of biological phenomenon and invaluable as evidence in support of conclusions.
We started generalizing result of community to individual Generalization
“ Game of Dice has became the  Game of life” Blaise Pascal
Double blind Randomized Placebo Controlled Trial Medical Evidence
We know by seeing But we see only what we know Probably we know better if we do not see All scientific invention are by extra sense To make common man believe we make revelation to visual observation Double Blind
Non Verbal Communication
Speed more than light, Instantaneous Receiving information beyond time  No weaning of power with distance  Never able to catch by any detectors Thoughts Waves
Quantum mechanics subatomic particle vibrating instantaneously at infinite distance Lattice theory universe is connected by subatomic lattice change in one part is transmitted to other part instantaneously Chaos theory small protuberance in one part cusses gross disturbance in distant  Theories of Telepathy
Placebo What happens when you do nothing Placebo Effect Doing nothing makes things happen A placebo (Latin for “I shall please”) is a medication or treatment believed by the administrator of the treatment to be inert or innocuous. The placebo effect is the measurable, observable, or felt improvement in health not attributable to treatment Placebo
Every subjective experience cannot be translated into words Translating into number is more abstract Most of the evidence are Visual or non numeric in Medicine. They are based on subjective interpretation. Translating them into number does not make them objective Subjective Evidence
History and Examination are subjective. Gold Standard of Medical Test Like Imaging and Pathology are Subjective Subjective Medical Evidences
Basis of Behaviour Conditional Reflex
Extrasensory input Subconscious  Integration Programming Art movement Memory Basis of Art
Sensory Extra-motor Extra-sensory Motor Integration Behavioural Reflex Input Output
A 1984 study in the  Annals of Internal Medicine  showed that doctors listened to patients for an average of eighteen seconds before interrupting. "Listen to the patient. He is telling you the diagnosis."  Dr. William Osler  Are we losing the  (art) of medicine?
“ Patient Satisfaction Measuring the Art of Medicine” Patient Satisfaction
Once the doctor used scientific studies to fit the treatment to the individual.  Now we fit the individual patient into the currently accepted treatment.  Tailoring to Readymade
rTPA in Acute ischemic Stroke 0.9mg/kg – Outcome 10% intracranial hemorrhage (EB) 0.5mg/kg – Outcome no Intracranial hemorrhage (NEB) Guidelines are not rules They are to Guide us not ride us Evidenced based rigidity
Behavior and Evidence Behaviour is not evidenced based
We believe what everybody says. If Everybody says king is wearing new cloth, he believes it Child can only see a truth Belief and Behavior
If we believe that EBM is the only way of healing, It works But Patient believes anything which helps healing Belief and Healing
Who is Benefited?
One who is innocent and faithful Who believe you as God Whatever intervention you do  Outcome is always Good Best patient
One who uses Knowledge with Wisdom Art with Science Evidence with Intuition Heart with Brain Best Doctor
 

Missing facts of Evidence Based Medicine

  • 1.
  • 2.
    Missing Facts of Evidence Based Medicine
  • 3.
    Thomas Kuhn Structureof Scientific Revolution 1962 Paradigm
  • 4.
    “ If itis spoken loudly with greater confidence and charisma” Truth
  • 5.
    A statement isa generator of prediction It is true if it generates only true predictions. Truth in Science
  • 6.
    Evidence is apiece of information that supports a conclusion What is Evidence?
  • 7.
    Past Event (Law)Future Event – Prediction (Medicine) Types of Evidence
  • 8.
    Source of EvidenceSubjective Objective
  • 9.
    For science, whatis real is only what can be counted or measured. Anything that is not visible is "unscientific" and therefore does not exist. Physical reality is the only reality. Objective Evidence
  • 10.
  • 11.
    Mathematics has becomethe language of science We started translating all natural phenomenon to Mathematics Any phenomenon can be presented in mathematical is taken as truth Maths and science
  • 12.
    Statistical Evidence Statisticshas become prime source of explanation of biological phenomenon and invaluable as evidence in support of conclusions.
  • 13.
    We started generalizingresult of community to individual Generalization
  • 14.
    “ Game ofDice has became the Game of life” Blaise Pascal
  • 15.
    Double blind RandomizedPlacebo Controlled Trial Medical Evidence
  • 16.
    We know byseeing But we see only what we know Probably we know better if we do not see All scientific invention are by extra sense To make common man believe we make revelation to visual observation Double Blind
  • 17.
  • 18.
    Speed more thanlight, Instantaneous Receiving information beyond time No weaning of power with distance Never able to catch by any detectors Thoughts Waves
  • 19.
    Quantum mechanics subatomicparticle vibrating instantaneously at infinite distance Lattice theory universe is connected by subatomic lattice change in one part is transmitted to other part instantaneously Chaos theory small protuberance in one part cusses gross disturbance in distant Theories of Telepathy
  • 20.
    Placebo What happenswhen you do nothing Placebo Effect Doing nothing makes things happen A placebo (Latin for “I shall please”) is a medication or treatment believed by the administrator of the treatment to be inert or innocuous. The placebo effect is the measurable, observable, or felt improvement in health not attributable to treatment Placebo
  • 21.
    Every subjective experiencecannot be translated into words Translating into number is more abstract Most of the evidence are Visual or non numeric in Medicine. They are based on subjective interpretation. Translating them into number does not make them objective Subjective Evidence
  • 22.
    History and Examinationare subjective. Gold Standard of Medical Test Like Imaging and Pathology are Subjective Subjective Medical Evidences
  • 23.
    Basis of BehaviourConditional Reflex
  • 24.
    Extrasensory input Subconscious Integration Programming Art movement Memory Basis of Art
  • 25.
    Sensory Extra-motor Extra-sensoryMotor Integration Behavioural Reflex Input Output
  • 26.
    A 1984 studyin the Annals of Internal Medicine showed that doctors listened to patients for an average of eighteen seconds before interrupting. "Listen to the patient. He is telling you the diagnosis." Dr. William Osler Are we losing the (art) of medicine?
  • 27.
    “ Patient SatisfactionMeasuring the Art of Medicine” Patient Satisfaction
  • 28.
    Once the doctorused scientific studies to fit the treatment to the individual. Now we fit the individual patient into the currently accepted treatment. Tailoring to Readymade
  • 29.
    rTPA in Acuteischemic Stroke 0.9mg/kg – Outcome 10% intracranial hemorrhage (EB) 0.5mg/kg – Outcome no Intracranial hemorrhage (NEB) Guidelines are not rules They are to Guide us not ride us Evidenced based rigidity
  • 30.
    Behavior and EvidenceBehaviour is not evidenced based
  • 31.
    We believe whateverybody says. If Everybody says king is wearing new cloth, he believes it Child can only see a truth Belief and Behavior
  • 32.
    If we believethat EBM is the only way of healing, It works But Patient believes anything which helps healing Belief and Healing
  • 33.
  • 34.
    One who isinnocent and faithful Who believe you as God Whatever intervention you do Outcome is always Good Best patient
  • 35.
    One who usesKnowledge with Wisdom Art with Science Evidence with Intuition Heart with Brain Best Doctor
  • 36.