Relaxation of a constraint / assumption
(1) Gaussian conditional distribution of the response (4) Independence of observations (within cluster, subject, level) (7) Conditional distribution of the response
comes from the one-parameter exponential family
(10) No outliers and other distributional issues
(2) Gaussian distribution of the random effects (5) Direct linearity in parameters. Models relationship between the conditional
(w.r.t. predictor) E(response) and the linear predictor. Unrelated mean and variance.
(8) Uncorrelated independent variables (11) Assumed / known conditional distribution
of the response
(3) Homoscedasticity (homogeneity of variance) (6) Indirect linearity in parameters. Models relationship between the function of
conditional (w.r.t. predictor) E(response) and the linear predictor.
(9) Non-truncated, non-censored response (12) Missing Completely At Random (MCAR)
(13) The residual covariance must be specified correctly (14) independent variables have been measured or observed without error (15) Population averaged parameters (16) Proportional odds
General Linear Model (via OLS)
(linear, linearized, polynomial
regression, ANCOVA)
General Linear Model via
Weighted OLS 
Generalized Least Square (GLS)
Generalized Linear Model (GLM)
(e.g. binomial: logistic/probit, gamma, Poisson, ordinal (proportional
odds) & multinomial logistic, log-linear, fractional logistic regression)
Vector Generalized Linear Model (VGLM)
(e.g. , 0-altered Poisson, positive Poisson, negative binomial, beta regression, 0-
1-inflated beta regression), partial proportional odds (PPO)
Generalized Estimating Equations (GEE)
GEE1= First Order, GEE2 = Second order
Weighted Generalized Estimating
Equations (WGEE)
{Generalized [Additive] [Non-Linear] }
(Robust) Mixed-Effect Model
LMM, (V)GLMM, GNMM, VGAMM
Generalised Additive Models for
Location Scale and Shape
(GAMLSS)
(Vector) Generalized Additive Model
([V] GAM)
General Non-Linear Model via Least Square
(GNLS)
Generalized Non-Linear Model (GNM)
Generalized Additive Main
effects and Multiplicative
Interaction (GAMMI)
Alternating Logistic
Regression (ALR)
Spatial Generalised Linear
Mixed Models (SGLMM)
Quantile Linear Model
Quantile Additive
Linear Model
Robust Models via M-estimators
(GLM, GAM)
Censored Regression
1-/2-sided Tobin’s model (tobit
regression)
Truncated Gaussian
Response Model
Linear Ordering Isotonic
Regression
Censored Models for Time-To-Event analysis
(Survival )
e.g. Cox (Proportional-hazard), Counting models
(Anderson-Gill, Prentice-Williams-Peterson, Wei-Lin-
Weissfeld), Competing risks (Fine-Gray), (Shared/Joint)
Frailty models Accelerated Failure Time (AFT),
Parametric survival (Weibull, Exponential, Gompertz,
gamma, Coale-McNeil), etc.
Regularization
(e.g. Ridge (Tikhonov), LASSO, elastic net)
(V)GAM, GLM,…
1
2
3
3
5
6
6
6
6
6
7
7
4
4
4
8
9
9
10
10
11
12
12
combines
7
Additive Main effects and
Multiplicative Interaction
(AMMI)
13
Errors-In-Variables Models
e.g. via Total Least Squares (TLS)
(e.g. Deming regression)
Passing-Bablock Regression
14
14
10
14
5
3
Generalized
Ordered Logit
16
Special case
Generalized Linear Latent And Mixed
Models (GLLAMM)
Special cases: Item-Reponse Theory models (IRT),
Generalized Linear Mixed Models (GLMM), Factor
Models, Structural Equation Models (SEM),
Latent Class Models
Special case
Dispersion Models
(e.g. simplex regression)

Modern statistical techniques

  • 1.
    Relaxation of aconstraint / assumption (1) Gaussian conditional distribution of the response (4) Independence of observations (within cluster, subject, level) (7) Conditional distribution of the response comes from the one-parameter exponential family (10) No outliers and other distributional issues (2) Gaussian distribution of the random effects (5) Direct linearity in parameters. Models relationship between the conditional (w.r.t. predictor) E(response) and the linear predictor. Unrelated mean and variance. (8) Uncorrelated independent variables (11) Assumed / known conditional distribution of the response (3) Homoscedasticity (homogeneity of variance) (6) Indirect linearity in parameters. Models relationship between the function of conditional (w.r.t. predictor) E(response) and the linear predictor. (9) Non-truncated, non-censored response (12) Missing Completely At Random (MCAR) (13) The residual covariance must be specified correctly (14) independent variables have been measured or observed without error (15) Population averaged parameters (16) Proportional odds General Linear Model (via OLS) (linear, linearized, polynomial regression, ANCOVA) General Linear Model via Weighted OLS  Generalized Least Square (GLS) Generalized Linear Model (GLM) (e.g. binomial: logistic/probit, gamma, Poisson, ordinal (proportional odds) & multinomial logistic, log-linear, fractional logistic regression) Vector Generalized Linear Model (VGLM) (e.g. , 0-altered Poisson, positive Poisson, negative binomial, beta regression, 0- 1-inflated beta regression), partial proportional odds (PPO) Generalized Estimating Equations (GEE) GEE1= First Order, GEE2 = Second order Weighted Generalized Estimating Equations (WGEE) {Generalized [Additive] [Non-Linear] } (Robust) Mixed-Effect Model LMM, (V)GLMM, GNMM, VGAMM Generalised Additive Models for Location Scale and Shape (GAMLSS) (Vector) Generalized Additive Model ([V] GAM) General Non-Linear Model via Least Square (GNLS) Generalized Non-Linear Model (GNM) Generalized Additive Main effects and Multiplicative Interaction (GAMMI) Alternating Logistic Regression (ALR) Spatial Generalised Linear Mixed Models (SGLMM) Quantile Linear Model Quantile Additive Linear Model Robust Models via M-estimators (GLM, GAM) Censored Regression 1-/2-sided Tobin’s model (tobit regression) Truncated Gaussian Response Model Linear Ordering Isotonic Regression Censored Models for Time-To-Event analysis (Survival ) e.g. Cox (Proportional-hazard), Counting models (Anderson-Gill, Prentice-Williams-Peterson, Wei-Lin- Weissfeld), Competing risks (Fine-Gray), (Shared/Joint) Frailty models Accelerated Failure Time (AFT), Parametric survival (Weibull, Exponential, Gompertz, gamma, Coale-McNeil), etc. Regularization (e.g. Ridge (Tikhonov), LASSO, elastic net) (V)GAM, GLM,… 1 2 3 3 5 6 6 6 6 6 7 7 4 4 4 8 9 9 10 10 11 12 12 combines 7 Additive Main effects and Multiplicative Interaction (AMMI) 13 Errors-In-Variables Models e.g. via Total Least Squares (TLS) (e.g. Deming regression) Passing-Bablock Regression 14 14 10 14 5 3 Generalized Ordered Logit 16 Special case Generalized Linear Latent And Mixed Models (GLLAMM) Special cases: Item-Reponse Theory models (IRT), Generalized Linear Mixed Models (GLMM), Factor Models, Structural Equation Models (SEM), Latent Class Models Special case Dispersion Models (e.g. simplex regression)