Movavi Video Editor Crack Crack Latest Verision 2025
- 1. Topic: Founder effect submitted by Abdul Raouf Roll No : BSBTE19-13 submitted to: Ms.Ghalia Batool Alvi
- 2. contents ๏ด Definition ๏ด Features ๏ด History ๏ด Modification ๏ด Causes ๏ด Graphical explanation ๏ด Examples
- 3. Founder Effect Definition The reduction in genetic variation that result when a small subset of a large population is used to establish a new colony
- 4. features ๏ด Reduction in genomic variability ๏ด Small group of individuals become separated from a large population ๏ด New subpopulation genotype and physical traits that resembling the initial small separated group and these may be very different from the original large population ๏ด Overcome the inherited diseases that are found more frequently in some limited population groups ๏ด Founder effect may change ๏ถ Height ๏ถ Weight ๏ถ Particular diseases
- 5. Discovery ๏ด Founder effect was developed by Mayer(1954) ๏ด Postulated ๏ด Genetic revelation could take place as a ๏ด By product of inbreeding ๏ด Selection ๏ด Drift ๏ด Genome reorganization ๏ด Morphological ๏ด Ecological shift
- 6. Modification Modification of founder effect was proposed by carson(1975) Founder flush model of speciation ๏ด Isolated population undergo a series of population expansion ๏ด Drastic construction to a very small numbers of individuals ๏ด Can occur only in certain cross fertilizing diploid organism with โopen genetic systemโ ๏ด The genome of Organism have abundant pleiotropic interacting ๏ด Genetic polymorphism ๏ด Share a high recombination of index
- 7. Causes ๏ด Geographical isolation ๏ด A particular area may become populated ๏ด with the small no of individuals ๏ด The origin of particular set of Y chromosomes ๏ด Polymorphism is passed through the generations Males with the same paternal ancestors are very likely to share identical Y chromosomes polymorphism know as a haplotype
- 8. Graphical representation a) q= o.5 possibility of polymorphism = 0.2 b) q= 0.2 possibility of polymorphism = 0.4 c) q= 0.1 possibility of polymorphism =0.6 result: I. as q value increase 1 fold the possibility of polymorphism increase 2 fold II. no of founder directly increase the no of possibility of polymorphism then gradually become constant
- 9. examples a) Incidence of genetic disease of Huntington disease (case 24) among the indigenous inhabitants around lake Maracaibo, Venezuela that resulted from the introduction of Huntington disease mutation into this genetic isolate. b)Hereditary type I tyrosinemia that causes hepatic failure and renal tubular dysfunction due to deficiency of fumarylacetoacetase a
- 10. Contโd 1. There are different colored flowers in a garden 2. A bird comes by and pics up a yellow flower and blue one 3. Then the bird drops some seed in another garden 4. The seed are fertilized and then only blue and yellow flowers grow in that garden