Nose & Para nasal sinus PROF. DR MASOOD AHMED MBBS,MPHIL,PHD
Nose & Paranasal sinus: Describe histological features of vestibular, respiratory and olfactory mucosa of nose  Describe histological features of mucous membrane Para nasal sinuses Identify under microscope the histological features of various parts of mucous membrane of nose and para nasal sinuses .
ANATOMY OF THE NOSE
Anatomy of the nose Vestibular part From anterior nostrils to inferior concha Respiratory part From inferior concha to the posterior nostril and up to the superior concha Olfactory part   Above the superior concha up to the roof of nose and adjoining part of septum
Anatomy of the nose Skeleton of nose is made up of bone and cartilages covered by mucous membrane  Surface lining of the three parts of the nose has different structure depending on the function
Para nasal sinuses Para nasal sinuses  are empty spaces  with in the skull bones around the nose. They open into the nose. They are lined by respiratory mucosa Named as frontal, maxillary, sphenoid and ethemoid
Nasal cavities
Vestibular part Covered by skin  Having coarse hairs called vibrissae Serve as initial filter to stop the entry of particulate material into the nose Sebaceous and sweat gland help in moistening and warming the the dried air
Respiratory mucosa Five type of cells present in epithelial lining Ciliated columnar cells, goblet cells, APUD cells, basal stem cells and brush cells with microvilli (sensory function) Mucous membrane adherent to underlying periosteum and perichondrium
Respiratory Mucus Membrane Respiratory part of nose and Para nasal sinuses are Lined by respiratory mucous membrane Psudostratified columnar ciliated epithelium with goblet cells Lamina propria containing mucous and serous glands Numerous thin walled veins specially over the inferior concha
Nasal Conchae
Nasal Conchae – spicule of bone covered with Resp Epith w/ a lamina propria w/ many veins
Diagram of the Olfactory Epithelium Psudostratified columnar cells with three didifferent type of cells L.P containing loose CT, BV and small serous glands and bundle of axons
OLFACTORY MUCOSA Psudostratified columnar ciliated epithelium Three type of cells True bipolar olfactory cells Sustentacular supporting cells & Basal stem cells
SEM of the surface of the Olfactory Epithelium From each Bipolar cells arise 12 non motile modified cilia from olfactory nobe  From basal end arise axone Pierce basement membrane Group of axons pierce cribriform plate
Olfactory mucosa Supporting cells Wider at upper end Long microvilli arising from this surface Junctional complexes present between two cells Serous glands called BOWMANS GLAND present in L.P
please note Mucous secretion traps the particulate matter Cilia sweep the mucous towards pharynx to swallow Numerous veins and mucous help in air conditioning (warming and moistening) Olfactory epithelium is yellowish in colour  Supporting cells have lipofucine pigment , may be phagocytic in function Bowmans gland secretion dissolve the content and help in olfaction

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Nose And Paranasal Sinusefinal

  • 1. Nose & Para nasal sinus PROF. DR MASOOD AHMED MBBS,MPHIL,PHD
  • 2. Nose & Paranasal sinus: Describe histological features of vestibular, respiratory and olfactory mucosa of nose Describe histological features of mucous membrane Para nasal sinuses Identify under microscope the histological features of various parts of mucous membrane of nose and para nasal sinuses .
  • 4. Anatomy of the nose Vestibular part From anterior nostrils to inferior concha Respiratory part From inferior concha to the posterior nostril and up to the superior concha Olfactory part Above the superior concha up to the roof of nose and adjoining part of septum
  • 5. Anatomy of the nose Skeleton of nose is made up of bone and cartilages covered by mucous membrane Surface lining of the three parts of the nose has different structure depending on the function
  • 6. Para nasal sinuses Para nasal sinuses are empty spaces with in the skull bones around the nose. They open into the nose. They are lined by respiratory mucosa Named as frontal, maxillary, sphenoid and ethemoid
  • 8. Vestibular part Covered by skin Having coarse hairs called vibrissae Serve as initial filter to stop the entry of particulate material into the nose Sebaceous and sweat gland help in moistening and warming the the dried air
  • 9. Respiratory mucosa Five type of cells present in epithelial lining Ciliated columnar cells, goblet cells, APUD cells, basal stem cells and brush cells with microvilli (sensory function) Mucous membrane adherent to underlying periosteum and perichondrium
  • 10. Respiratory Mucus Membrane Respiratory part of nose and Para nasal sinuses are Lined by respiratory mucous membrane Psudostratified columnar ciliated epithelium with goblet cells Lamina propria containing mucous and serous glands Numerous thin walled veins specially over the inferior concha
  • 12. Nasal Conchae – spicule of bone covered with Resp Epith w/ a lamina propria w/ many veins
  • 13. Diagram of the Olfactory Epithelium Psudostratified columnar cells with three didifferent type of cells L.P containing loose CT, BV and small serous glands and bundle of axons
  • 14. OLFACTORY MUCOSA Psudostratified columnar ciliated epithelium Three type of cells True bipolar olfactory cells Sustentacular supporting cells & Basal stem cells
  • 15. SEM of the surface of the Olfactory Epithelium From each Bipolar cells arise 12 non motile modified cilia from olfactory nobe From basal end arise axone Pierce basement membrane Group of axons pierce cribriform plate
  • 16. Olfactory mucosa Supporting cells Wider at upper end Long microvilli arising from this surface Junctional complexes present between two cells Serous glands called BOWMANS GLAND present in L.P
  • 17. please note Mucous secretion traps the particulate matter Cilia sweep the mucous towards pharynx to swallow Numerous veins and mucous help in air conditioning (warming and moistening) Olfactory epithelium is yellowish in colour Supporting cells have lipofucine pigment , may be phagocytic in function Bowmans gland secretion dissolve the content and help in olfaction