Subtitle
PAIN MANAGEMENT
INTRODUCTION
1. Introduction
Definition: Pain is ā€œan unpleasant sensory and emotional
experienceā€ – Associated with actual or potential tissue damage, or
described in terms of such damageā€
• ā€œPain is what the patient says hurtsā€
* Purpose of Pain: Acute — acts as a protective signal; Chronic —
often becomes a maladaptive disease state .
* Epidemiology: Affects millions worldwide, with chronic pain (>3
months) leading cause of disability .
CLASSIFICATION
2. Classification
1.ACUTE
2.SUBACUTE
3.CHRONIC
a. Non malignant
b.Malignant
CLASSIFICATION
2. Classification
A. By Duration (per Harrison & AMBOSS)
TYPE
Acute
Subacute
Chronic
DURATION
<1 Month
1-3
Months
>3 Months
ROLE
Protective signal of
tissue damage
Transition phase
Independent
diseases;
biopsychosocial
ACUTE PAIN
• Injury, trauma, spasm or disease to
skin, muscle, somatic structures or
viscera;
• Perceived and communicated via
peripheral mechanisms (pathways)
• Usually associated with autonomic
response as well (tachycardia,Ā­blood
pressure, diaphoresis, pallor,
mydriasis (pupil dilation).
CHRONIC PAIN
a.Non-malignant
• Pain persists beyond the
precipitating injury
• Rarely accompanied by autonomic
symptoms
• Sufferers often fail to demonstrate
objective evidence of underlying
pathology.
• Characterized by location-visceral,
myofascial, or neurologic causes.
CHRONIC PAIN
b.Malignant
• Has characteristics of chronic
pain as well as symptoms of
acute pain (breakthrough pain).
• Has a definable cause, e.g.
tumour recurrence
• In treatment, narcotic
habituation is generally not a
concern.
DIFFERENCE BETWEEN ACUTE & CHRONIC PAIN
CLASSIFICATION
2. Classification
B. By Mechanism (Harrison & IASP-INTERNATIONAL ASSOCIATION FOR THE STUDY OF PAIN)
Nociceptive: Tissue injury — superficial, deep, or visceral
Neuropathic: Nerve damage — peripheral (ā€œburningā€, ā€œtinglingā€) or central
Nociplastic: Abnormal amplification without clear tissue damage
Types of pain
Types of pain
Based on Mechanism (Harrison & IASP-INTERNATIONAL ASSOCIATION FOR THE STUDY OF PAIN)
1.Nociceptive pain: Due to activation of nociceptors by tissue damage or inflammation
* somatic pain: skin,bone,muscle (sharp well-localised)
Example: Fracture, incision, arthritis
* Visceral Pain: Internal organs (dull, poorly localized, cramping)
Example: Appendicitis, gallstones, ischemia
2.Neuropathic pain: Caused by nerve damage (peripheral or central nervous system)
* Peripheral: Diabetic neuropathy, trigeminal neuralgia
*Central: Stroke, multiple sclerosis
*Descriptors*: Burning, tingling, electric-shock-like
3. Nociplastic pain: Altered pain processing without clear tissue or nerve damage
• Common in fibromyalgia, chronic tension headache, irritable bowel syndrome
• Pain is widespread, variable, and not explained by structural damage
Types of pain
Based on duration
A. By Duration (per Harrison & AMBOSS)
TYPE
Acute
Subacute
Chronic
DURATION
<1 Month
1-3
Months
>3 Months
DESCRIPTION
Sudden onset, protective
function, linked to injury
Transition between acute
and chronic
Persistent, may become a
disease in itself
Examples of Chronic Pain:
* Chronic back pain
* Osteoarthritis
* Phantom limb pain
* Post-herpetic neuralgia
Types of pain
Based on causes (ICD-11)
1. Chronic Primary Pain
* Pain is the disease itself
* Includes:
* Fibromyalgia
* Chronic widespread pain
* Non-specific low back pain
2. Chronic Secondary Pain
* Pain is a symptom of another condition
* Subtypes:
* Cancer-related pain
* Post-surgical/post-traumatic pain
* Neuropathic pain
* Visceral pain (IBD, endometriosis)
* Musculoskeletal pain (RA, OA)
Pain Assessment
Pain Assessment
Pain History
SOCRATES
SITE OF PAIN- Somatic pain-well localized
visceral pain-more diffuse(angina)
ONSET- Speed of onset and any associations
CHARACTERISTIC OF PAIN- Example: sharp,dull,burning,tingling,stabbing,crushing
RADIATION OF PAIN
ASSOCIATED SYMPTOMS
TIME/DURIATION OF PAIN
EXACERBATING FACTORS
SEVERITY OF PAIN
Pain Assessment
Pain History
• Other important additional questions to be asked.
• What is the response to past and current analgesic therapy?
• Any kind of diary or record about the pain?
• Fears they have about analgesics?
Pain Assessment
Pain assessment tools
Numeric rating scale
Verbal descriptive Scales.
Visual Analogue Scales.
McGill pain questionnaire
Factors to consider in choosing a pain scale
1. Age of patient
2. Physical condition
3. Level of consciousness
4. Mental status
5. Ability to communicate
Pain Assessment
Numeric Pain Rating Scale
• Ask the patient to rate their pain intensity on a scale of 0 (no pain) to 10
(the worst pain imaginable).
• Some patients are unable to do this with only verbal instructions, but may
be able to look at a number scale and point to the number that describes the
intensity of pain
Pain Assessment
• Wong-Baker FACES Pain Rating Scale
• Can be used with young children (sometimes as young as 3 years of age)
• Works well for many older children and adults as well as for those who
speak a different language
• Explain that each face represents a person who may have no pain, some
pain, or as much pain as imaginable. Point to the appropriate face and
say the appropriate description. e.g. ā€œThis face hurts just a little bitā€
Pain Assessment
• Wong-Baker FACES Pain Rating Scale
• Ask the patient to choose the face that best matches how she or he feels or
how much they hurt.
Pain Assessment
Color Pain Rating Scale
• Ask the patient to point to the area on the scale that shows their level of
pain from white (no pain) to dark red (worst possible pain).
• Obtain a number corresponding to the area where the patient points.
Pain Assessment
Severity Assessment
• McGill Pain Questionnaire
• Scale from 0 to 5
• From None to Severe Pain
• for children or adults who understand numerical relationships.
Pain Assessment
PAIN ASSESSMENT Tools
Pain treatment
Pain treatment
Goals of Pain Management Therapy
1) Decreased pain
2) Decreased healthcare utilization
o Decreased ā€œshoppingā€ for care
o Decreased emergency room visits
3) Improved functional status
o Increased ability to perform activities of daily living
o Return to employment
Pain treatment
Management
• Non-Pharamcological treatment
• Pharmacological treatment:
• Analgesics
• NSAIDs
• Adjuvants
• Others
Pain treatment
Non-pharmacological interventions
• Exercise
• Weight reduction
• Counseling
• Smoking cessation
• Massage ,Relaxation therapy
• Heat & cold applications
Pain treatment
Pharmacological interventions
Analgesics
1. Non opioid
‑ Analgesics (Step 1 WHO Ladder)
Acetaminophen (Paracetamol)
* Adults: 500–1,000 mg PO every 6 hours, max 4 g/day.
* Children: 15 mg/kg PO/PR q4–6 h, max 60 mg/kg/day (max 4 g/day)
Pain treatment
Pharmacological interventions
Analgesics
• NSAIDs
• 1. Ibuprofen 400–800 mg PO every 6 hours (max 3,200 mg/day) .
• 2. Diclofenac 50 mg PO q8 h or 75 mg PO bid (max 200 mg/day) .
• 3. Ketorolac IV/IM 15–30 mg q6 h (max 120 mg/day, ≤ 5 days)
• 4. Meloxicam 7.5–15 mg PO q24 h
• 5. Celecoxib 200 mg PO q12 h .
• āš ļøUse NSAIDs cautiously with renal, cardiovascular, or GI comorbidities
Pain treatment
Pharmacological interventions
Analgesics
2. Weak Opioids (Step 2 WHO Ladder)
Tramadol
* Adults: 50–100 mg PO every 4–6 h PRN; max 400 mg/day .
* Parenteral: 50–100 mg IV/IM q4–6 h PRN .
Codeine combos
* Codeine + Acetaminophen: 1–2 tablets every 4 hours PRN (e.g., 30 mg
codeine + 300 mg APAP) .
Pain treatment
Pharmacological interventions
Analgesics
3. Strong Opioids (Step 3 WHO Ladder)
Morphine
* Immediate-release: 10 mg PO q4 h PRN (typical replacement for IV dose 
~0.1–0.2 mg/kg IV q4 h) .
* Modified-release: 10–60 mg PO q12 h (dose-titrated) .
* Injectable: 10 mg/mL ampules; IV dosing as above
Oxycodone
* Controlled-release: 10 mg PO q12 h
Pain treatment
Pharmacological interventions
Analgesics
3. Strong Opioids (Step 3 WHO Ladder)
Fentanyl
* Injectable: 0.35–0.5 µg/kg IV every 30–60 min PRN
* Transdermal patch: used when oral intake not possible; dosing per product.
Buprenorphine
* Transdermal for chronic pain—dosing per product guidelines .
Pain treatment
Pharmacological interventions
Adjuvants
4. Adjuvants / Ancillaries
* Antidepressants (e.g., amitriptyline, nortriptyline,
SNRIs) for neuropathic pain.
* Anticonvulsants (e.g., gabapentin/pregabalin).
* Steroids, bisphosphonates, ziconotide (intrathecal) for
specific cancer pain scenarios .
Pain treatment
Pharmacological interventions
5. Special Populations
* Children: Use age-appropriate preparations and weight-based dosing (e.g.,
ibuprofen 200 mg/5 mL syrup; paracetamol 120 mg/5 mL).
* Elderly / Renal/Hepatic impairment: Start lower, titrate up cautiously for
opioids and NSAIDs .
Pain treatment
Choosing the Appropriate Analgesic
• Match the severity of pain to the strength of the analgesic i.e. strong
analgesics for severe pain.
• The WHO has developed 3-step model to guide analgesic choice
depending on the severity of the patient’s pain.
Pain treatment
WHO Pain Management Ladder
 Step I:
ļ‚§ NSAIDS ± adjuvants
 Step II:
ļ‚§ NSAID + Mild opioids ± adjuvant
 Step III:
ļ‚§ Strong opioids + NSAIDS ± adjuvants
Pain treatment
Other modalities
• Nerve blocks, epidural blocks and ablative neurosurgical
procedures may be effective in pain management.
• Such procedures may be associated with return of pain
after a number of months so that timing of procedures may
be important.
THANK YOU

Pain management ppt from Harrison for study purpose

  • 1.
  • 5.
    INTRODUCTION 1. Introduction Definition: Painis ā€œan unpleasant sensory and emotional experienceā€ – Associated with actual or potential tissue damage, or described in terms of such damageā€ • ā€œPain is what the patient says hurtsā€ * Purpose of Pain: Acute — acts as a protective signal; Chronic — often becomes a maladaptive disease state . * Epidemiology: Affects millions worldwide, with chronic pain (>3 months) leading cause of disability .
  • 6.
  • 7.
    CLASSIFICATION 2. Classification A. ByDuration (per Harrison & AMBOSS) TYPE Acute Subacute Chronic DURATION <1 Month 1-3 Months >3 Months ROLE Protective signal of tissue damage Transition phase Independent diseases; biopsychosocial
  • 8.
    ACUTE PAIN • Injury,trauma, spasm or disease to skin, muscle, somatic structures or viscera; • Perceived and communicated via peripheral mechanisms (pathways) • Usually associated with autonomic response as well (tachycardia,Ā­blood pressure, diaphoresis, pallor, mydriasis (pupil dilation).
  • 9.
    CHRONIC PAIN a.Non-malignant • Painpersists beyond the precipitating injury • Rarely accompanied by autonomic symptoms • Sufferers often fail to demonstrate objective evidence of underlying pathology. • Characterized by location-visceral, myofascial, or neurologic causes.
  • 10.
    CHRONIC PAIN b.Malignant • Hascharacteristics of chronic pain as well as symptoms of acute pain (breakthrough pain). • Has a definable cause, e.g. tumour recurrence • In treatment, narcotic habituation is generally not a concern.
  • 11.
  • 12.
    CLASSIFICATION 2. Classification B. ByMechanism (Harrison & IASP-INTERNATIONAL ASSOCIATION FOR THE STUDY OF PAIN) Nociceptive: Tissue injury — superficial, deep, or visceral Neuropathic: Nerve damage — peripheral (ā€œburningā€, ā€œtinglingā€) or central Nociplastic: Abnormal amplification without clear tissue damage
  • 13.
  • 14.
    Types of pain Basedon Mechanism (Harrison & IASP-INTERNATIONAL ASSOCIATION FOR THE STUDY OF PAIN) 1.Nociceptive pain: Due to activation of nociceptors by tissue damage or inflammation * somatic pain: skin,bone,muscle (sharp well-localised) Example: Fracture, incision, arthritis * Visceral Pain: Internal organs (dull, poorly localized, cramping) Example: Appendicitis, gallstones, ischemia 2.Neuropathic pain: Caused by nerve damage (peripheral or central nervous system) * Peripheral: Diabetic neuropathy, trigeminal neuralgia *Central: Stroke, multiple sclerosis *Descriptors*: Burning, tingling, electric-shock-like 3. Nociplastic pain: Altered pain processing without clear tissue or nerve damage • Common in fibromyalgia, chronic tension headache, irritable bowel syndrome • Pain is widespread, variable, and not explained by structural damage
  • 15.
    Types of pain Basedon duration A. By Duration (per Harrison & AMBOSS) TYPE Acute Subacute Chronic DURATION <1 Month 1-3 Months >3 Months DESCRIPTION Sudden onset, protective function, linked to injury Transition between acute and chronic Persistent, may become a disease in itself Examples of Chronic Pain: * Chronic back pain * Osteoarthritis * Phantom limb pain * Post-herpetic neuralgia
  • 16.
    Types of pain Basedon causes (ICD-11) 1. Chronic Primary Pain * Pain is the disease itself * Includes: * Fibromyalgia * Chronic widespread pain * Non-specific low back pain 2. Chronic Secondary Pain * Pain is a symptom of another condition * Subtypes: * Cancer-related pain * Post-surgical/post-traumatic pain * Neuropathic pain * Visceral pain (IBD, endometriosis) * Musculoskeletal pain (RA, OA)
  • 17.
  • 18.
    Pain Assessment Pain History SOCRATES SITEOF PAIN- Somatic pain-well localized visceral pain-more diffuse(angina) ONSET- Speed of onset and any associations CHARACTERISTIC OF PAIN- Example: sharp,dull,burning,tingling,stabbing,crushing RADIATION OF PAIN ASSOCIATED SYMPTOMS TIME/DURIATION OF PAIN EXACERBATING FACTORS SEVERITY OF PAIN
  • 19.
    Pain Assessment Pain History •Other important additional questions to be asked. • What is the response to past and current analgesic therapy? • Any kind of diary or record about the pain? • Fears they have about analgesics?
  • 20.
    Pain Assessment Pain assessmenttools Numeric rating scale Verbal descriptive Scales. Visual Analogue Scales. McGill pain questionnaire Factors to consider in choosing a pain scale 1. Age of patient 2. Physical condition 3. Level of consciousness 4. Mental status 5. Ability to communicate
  • 21.
    Pain Assessment Numeric PainRating Scale • Ask the patient to rate their pain intensity on a scale of 0 (no pain) to 10 (the worst pain imaginable). • Some patients are unable to do this with only verbal instructions, but may be able to look at a number scale and point to the number that describes the intensity of pain
  • 22.
    Pain Assessment • Wong-BakerFACES Pain Rating Scale • Can be used with young children (sometimes as young as 3 years of age) • Works well for many older children and adults as well as for those who speak a different language • Explain that each face represents a person who may have no pain, some pain, or as much pain as imaginable. Point to the appropriate face and say the appropriate description. e.g. ā€œThis face hurts just a little bitā€
  • 23.
    Pain Assessment • Wong-BakerFACES Pain Rating Scale • Ask the patient to choose the face that best matches how she or he feels or how much they hurt.
  • 24.
    Pain Assessment Color PainRating Scale • Ask the patient to point to the area on the scale that shows their level of pain from white (no pain) to dark red (worst possible pain). • Obtain a number corresponding to the area where the patient points.
  • 25.
    Pain Assessment Severity Assessment •McGill Pain Questionnaire • Scale from 0 to 5 • From None to Severe Pain • for children or adults who understand numerical relationships.
  • 26.
  • 27.
  • 28.
    Pain treatment Goals ofPain Management Therapy 1) Decreased pain 2) Decreased healthcare utilization o Decreased ā€œshoppingā€ for care o Decreased emergency room visits 3) Improved functional status o Increased ability to perform activities of daily living o Return to employment
  • 29.
    Pain treatment Management • Non-Pharamcologicaltreatment • Pharmacological treatment: • Analgesics • NSAIDs • Adjuvants • Others
  • 30.
    Pain treatment Non-pharmacological interventions •Exercise • Weight reduction • Counseling • Smoking cessation • Massage ,Relaxation therapy • Heat & cold applications
  • 31.
    Pain treatment Pharmacological interventions Analgesics 1.Non opioid ‑ Analgesics (Step 1 WHO Ladder) Acetaminophen (Paracetamol) * Adults: 500–1,000 mg PO every 6 hours, max 4 g/day. * Children: 15 mg/kg PO/PR q4–6 h, max 60 mg/kg/day (max 4 g/day)
  • 32.
    Pain treatment Pharmacological interventions Analgesics •NSAIDs • 1. Ibuprofen 400–800 mg PO every 6 hours (max 3,200 mg/day) . • 2. Diclofenac 50 mg PO q8 h or 75 mg PO bid (max 200 mg/day) . • 3. Ketorolac IV/IM 15–30 mg q6 h (max 120 mg/day, ≤ 5 days) • 4. Meloxicam 7.5–15 mg PO q24 h • 5. Celecoxib 200 mg PO q12 h . • āš ļøUse NSAIDs cautiously with renal, cardiovascular, or GI comorbidities
  • 33.
    Pain treatment Pharmacological interventions Analgesics 2.Weak Opioids (Step 2 WHO Ladder) Tramadol * Adults: 50–100 mg PO every 4–6 h PRN; max 400 mg/day . * Parenteral: 50–100 mg IV/IM q4–6 h PRN . Codeine combos * Codeine + Acetaminophen: 1–2 tablets every 4 hours PRN (e.g., 30 mg codeine + 300 mg APAP) .
  • 34.
    Pain treatment Pharmacological interventions Analgesics 3.Strong Opioids (Step 3 WHO Ladder) Morphine * Immediate-release: 10 mg PO q4 h PRN (typical replacement for IV dose ~0.1–0.2 mg/kg IV q4 h) . * Modified-release: 10–60 mg PO q12 h (dose-titrated) . * Injectable: 10 mg/mL ampules; IV dosing as above Oxycodone * Controlled-release: 10 mg PO q12 h
  • 35.
    Pain treatment Pharmacological interventions Analgesics 3.Strong Opioids (Step 3 WHO Ladder) Fentanyl * Injectable: 0.35–0.5 µg/kg IV every 30–60 min PRN * Transdermal patch: used when oral intake not possible; dosing per product. Buprenorphine * Transdermal for chronic pain—dosing per product guidelines .
  • 36.
    Pain treatment Pharmacological interventions Adjuvants 4.Adjuvants / Ancillaries * Antidepressants (e.g., amitriptyline, nortriptyline, SNRIs) for neuropathic pain. * Anticonvulsants (e.g., gabapentin/pregabalin). * Steroids, bisphosphonates, ziconotide (intrathecal) for specific cancer pain scenarios .
  • 37.
    Pain treatment Pharmacological interventions 5.Special Populations * Children: Use age-appropriate preparations and weight-based dosing (e.g., ibuprofen 200 mg/5 mL syrup; paracetamol 120 mg/5 mL). * Elderly / Renal/Hepatic impairment: Start lower, titrate up cautiously for opioids and NSAIDs .
  • 38.
    Pain treatment Choosing theAppropriate Analgesic • Match the severity of pain to the strength of the analgesic i.e. strong analgesics for severe pain. • The WHO has developed 3-step model to guide analgesic choice depending on the severity of the patient’s pain.
  • 39.
    Pain treatment WHO PainManagement Ladder  Step I: ļ‚§ NSAIDS ± adjuvants  Step II: ļ‚§ NSAID + Mild opioids ± adjuvant  Step III: ļ‚§ Strong opioids + NSAIDS ± adjuvants
  • 40.
    Pain treatment Other modalities •Nerve blocks, epidural blocks and ablative neurosurgical procedures may be effective in pain management. • Such procedures may be associated with return of pain after a number of months so that timing of procedures may be important.
  • 41.