Panel 2:
Optimizing Integrated
Colorectal Cancer Treatment
Planning and Patient Support
Panelists:
Michael Loreto MD FRCP(C)
Kathleen Callaghan BSC RN ET
Julie Whitten BSc RD
Traci Franklin MSW RSW
Mr. TW: Case History 2
• Colonoscopy reveals a rectal cancer
• A rectal MRI for pre-operative staging
reveals Stage III rectal cancer
• Pre-operative chemo-radiotherapy, then a
total mesorectal excision followed by postoperative chemotherapy
• Mr. TW has a temporary colostomy, has
bowel habit changes and feels depressed
Role of MRI in Staging and
Treatment Decisions for Patients
with Rectal Cancer
Dr. Michael Loreto
Associate Radiologist, Health Sciences North
Which patients benefit from a
pre-operative MRI?
ALL patients with rectal cancer should have a pre-operative
MRI as hi-resolution MRI has become the diagnostic
standard for the accurate LOCAL STAGING of rectal
cancer.
What information does a preoperative MRI provide?
• Local staging
– primary tumour (T-stage)
– regional lymph nodes (N)
Assessment of the Primary
Tumour – T-stage
Modified TNM Staging (AJCC)
StageT2

Hi-res T2-weighted axial (short-axis) image
Kaur H et al. RadioGraphics (2012)
“early stage” T3

Kaur H et al. RadioGraphics (2012)

“advanced stage” T3
How does rectal MRI influence
treatment decisions?
• Identification of patients who may benefit from preoperative chemoradiation
• Surgical planning
Neo-adjuvant Treatment
• Current Cancer Care Ontario (CCO) guidelines:
– Pre-operative chemoradiation for stage II (T3-T4N0) and stage III
(T1-4N1-2) primary rectal cancer

• Recommendations based on multiple RCTs showing that
pre-op RT and pre-op CRT significantly reduce the risk
of local recurrence
Low Rectal Cancers
•

Lower extent between 0 – 5 cm from the anal verge

•

Lower extent above the top border of the puborectalis may be amenable to sphinctersparing surgery

•

Lower extent at or below the top border of the puborectalis will require abdominal
perineal resection (T1 and early T2), extralevator APR (advanced T2 and T3) or
pelvic exenteration (T4)
CCO Synoptic Report for Rectal Cancer
• In an attempt to standardize reporting, CCO has
developed an evidence-based synoptic report template
that radiologists have been encouraged to utilize

• Report template includes important rectal tumour
characteristics that influence neo-adjuvant and surgical
treatment decisions
How are rectal cancer treatment
decisions made at HSN?
• Rectal cancer cases are discussed at multidisciplinary
case conferences (MCC) on a weekly basis
• Imaging is reviewed by the radiologist, and treatment
decisions are discussed amongst the attending medical
oncologists, radiation oncologists and surgeons
Summary
• Rectal MRI is the diagnostic standard for local staging of primary
rectal cancer
• CCO has created an evidence-based synoptic report emphasizing
key findings to help identify patients requiring neo-adjuvant
treatment and to assist surgeons in determining the type/extent of
surgery required
• Multidisciplinary case conferences at HSN ensure that proper
discussion occurs between radiologists, oncologists and surgeons
prior to a treatment plan being implemented
References
1.

Taylor FGM et al. A Systematic Approach to the Interpretation of Preoperative
Staging MRI for Rectal Cancer. AJR: 191; pp.1827-1835 (2008).

2.

Kaur H et al. MRI Imaging for Preoperative Evaluation of Primary Rectal Cancer:
Practical Considerations. RadioGraphics: 32; pp.389-409 (2012).

3.

Cancer Care Ontario User’s Guide for the Synoptic MRI Report for Rectal Cancer
(https://www.cancercare.on.ca).
Role of the Enterostomal
Therapist
Kathleen Callaghan BScN RN ET
Enterostomal Therapist
Nurse Continence Advisor, HSN
Nutrition Intervention During
Rectal Cancer Treatment
Julie Whitten, B.Sc., RD
Supportive Care Program
Northeast Cancer Centre, HSN
Nutrition Intervention During Rectal
Cancer Treatment
• Automatic nutrition referral

• Monitor bowel function and nutritional
status throughout treatment
Symptom Management Guidelines
Nutrition Interventions
Nutrition Interventions
• Low Roughage, Low Fibre Diet
– Avoid insoluble fibre
– Focus on soluble fibre

• Fluid intake
–
–
–
–

Increased fluid needs
Avoid hyper-osmotic fluids (fruit drinks, sodas)
Oral rehydration solutions
Parenteral hydration

• Limit caffeine, alcohol, fried/greasy foods, carbonated
beverages
• Small, frequent meals at regular times
Symptom Management Guidelines
Pharmacological Interventions
Psychosocial Care for
Colorectal Cancer
Traci Franklin MSW RSW
Supportive Care Program
Northeast Cancer Centre, HSN
ESAS Guidelines: Depression
Depression in Cancer
•
•
•
•

Mood
Affect
Thoughts: hopeless, helpless
Fears:
– Disability, loss of roles, disfigurement,
loss of control, loss of support, dying,
pain
– Feeling they are being punished
Depression in Cancer
• The prevalence of significant emotional
distress, defined as anxiety, depression,
and adjustment disorders, ranges from
35% to 45% across studies in North
America (Carlson & Bultz, 2003; Zabora,
Brintzenhofeszoc, Curbow, Hooker &
Piantadosi, 2001)
Psychosocial Factors
 Sexual Dysfunction
 pelvic surgery, radiotherapy
 Body Image
 colostomy
 Relational Adjustment
 Anxiety about bowel incontinence
 Financial Concerns
 Cost of supplies
 Coping with Side effects of Treatment
ESAS GUIDELINES
Depression: 4-6

More Related Content

PPT
State of the Art Radiotherapy in the Treatment of Colorectal Cancer: What Exa...
PPT
Meeting the Cancer Survivorship Needs of Colorectal Cancer: The Wellness Beyo...
PPTX
Panel 3: Creating a Responsive Health Care System for Patients With Advanced ...
PPT
Northeast Case for Action: Colorectal Cancer, Mr. Mark Hartman
PPTX
FAST Forward Trial breast cancer
PPTX
Journal alternative
PDF
Nrclinonc.2011.81
PPTX
Bevacizumab plus m folfox6 versus mfolfox6 alone as first line
State of the Art Radiotherapy in the Treatment of Colorectal Cancer: What Exa...
Meeting the Cancer Survivorship Needs of Colorectal Cancer: The Wellness Beyo...
Panel 3: Creating a Responsive Health Care System for Patients With Advanced ...
Northeast Case for Action: Colorectal Cancer, Mr. Mark Hartman
FAST Forward Trial breast cancer
Journal alternative
Nrclinonc.2011.81
Bevacizumab plus m folfox6 versus mfolfox6 alone as first line

What's hot (20)

PPTX
Discuss the principles guiding the use of radiotherapy in surgery
PDF
2014 Ovarian Cancer National Conference: Launching the Women's Cancer Moonshot
PPTX
Liver first approach for CRLM
PPTX
EPAD 2017 - Jochen Walz
PPTX
Screening for occult cancer in unprovoked venous
PPTX
One example of how Clinical Cancer Registry level data can review practice va...
PDF
Survivorship Care Plans
PPTX
Fifth Annual Metastatic Breast Cancer Forum
PPT
POC Breast 1 | 2007 - Adjuvant Trastuzumab
 
PPT
Brian Sick, M.D.
PPTX
Discuss the role of precision medicine in breast cancer
PPT
2009 PET Review And NOPR Update
PPT
Prostate Cancer Navigation
PPTX
Predictors of MDT review and the impact on lung cancer survival for HNELHD re...
PDF
Current Issues Affecting Cancer Care in Puerto Rico
PPTX
The Lung Cancer Demonstration Project: Implementation and evaluation of a lun...
PPTX
EPAD 2017 Ian Banks
PPTX
Weight loss among patients with Head and Neck Cancer at St Vincent's Hospital...
PPTX
Clinical Trials 101
PPTX
Targeted Therapy for Uveal Melanoma - Richard Carvajal, MD
Discuss the principles guiding the use of radiotherapy in surgery
2014 Ovarian Cancer National Conference: Launching the Women's Cancer Moonshot
Liver first approach for CRLM
EPAD 2017 - Jochen Walz
Screening for occult cancer in unprovoked venous
One example of how Clinical Cancer Registry level data can review practice va...
Survivorship Care Plans
Fifth Annual Metastatic Breast Cancer Forum
POC Breast 1 | 2007 - Adjuvant Trastuzumab
 
Brian Sick, M.D.
Discuss the role of precision medicine in breast cancer
2009 PET Review And NOPR Update
Prostate Cancer Navigation
Predictors of MDT review and the impact on lung cancer survival for HNELHD re...
Current Issues Affecting Cancer Care in Puerto Rico
The Lung Cancer Demonstration Project: Implementation and evaluation of a lun...
EPAD 2017 Ian Banks
Weight loss among patients with Head and Neck Cancer at St Vincent's Hospital...
Clinical Trials 101
Targeted Therapy for Uveal Melanoma - Richard Carvajal, MD
Ad

Viewers also liked (20)

PPT
MCC 2011 - Slide 21
PPTX
Management of patients with primary colorectal cancer and
PPT
COLON CANCER
PPT
The Surgery for Rectal Cancer
PDF
Colorectal Cancer
PPTX
Surgical resections and staging of colorectal carcinoma
PPTX
Epigenética en cáncer colorectal Pablo Argibay
PPTX
What's New in Colorectal Cancer Research?
PPTX
Systematic Review and Meta-Analysis of histopathological factors influencing ...
PPTX
The ticking bomb in the abdomen diverticular disease
PPTX
EXPLORACION DE VIAS URINARIAS 2013 2
PPTX
Colorectal Cancer Research & Treatment News - recap from the May 2014 ASCO co...
PPTX
TMS Therapy at Pilsen Wellness Center
PPTX
surgical manag of colorectal liver mets
PPT
NON HODGKIN’S LYMPHOMA OF ORAL CAVITY /prosthodontic courses
PPTX
Role of surgery in metastatic colorectal cancer
PPTX
CARCINOMA RECTUM MANAGEMENT
PPT
Cco metastatic colorectal_cancer_cases_slides
PPTX
Carcinoma rectum-radiotherapy perspective
PPTX
Patologia quirurgica de colon, recto y ano para internet
MCC 2011 - Slide 21
Management of patients with primary colorectal cancer and
COLON CANCER
The Surgery for Rectal Cancer
Colorectal Cancer
Surgical resections and staging of colorectal carcinoma
Epigenética en cáncer colorectal Pablo Argibay
What's New in Colorectal Cancer Research?
Systematic Review and Meta-Analysis of histopathological factors influencing ...
The ticking bomb in the abdomen diverticular disease
EXPLORACION DE VIAS URINARIAS 2013 2
Colorectal Cancer Research & Treatment News - recap from the May 2014 ASCO co...
TMS Therapy at Pilsen Wellness Center
surgical manag of colorectal liver mets
NON HODGKIN’S LYMPHOMA OF ORAL CAVITY /prosthodontic courses
Role of surgery in metastatic colorectal cancer
CARCINOMA RECTUM MANAGEMENT
Cco metastatic colorectal_cancer_cases_slides
Carcinoma rectum-radiotherapy perspective
Patologia quirurgica de colon, recto y ano para internet
Ad

Similar to Panel 2: Optimizing Integrated Colorectal Cancer Treatment Planning and Patient Support, Dr. Michael Loreto, Ms. Kathleen Callaghan, Ms. Julie Whitten, Ms. Traci Franklin (20)

PPTX
approach for rectal carcinoma and management
PPTX
St gallen rectal carcinoma
PPTX
Staging and Diagnostic approach of rectal cancer
PPTX
final final recRectal carcinoma ca.pptx
PPTX
Imaging in MRI of rectal carcinoma .pptx
PDF
the-multimodal-management-of-locally-advanced-rectal-cancer-making-sense-o.pdf
PPTX
Rectal cancer
PPTX
Carcinoma rectum
PPTX
Recent Advances in Radiation Therapy for Rectal Cancer.pptx
PPTX
Rectal carcinoma approach
PPTX
Rectal cancer MRI (for staging of CA rectum), Dr. Adnan Rashid, MD
PPTX
Management of Rectal cancer.pptx
PPTX
Highlights in the treatment of Rectal cancer.pptx
PPT
MCC 2011 - Slide 2
PPTX
Ca rectum Management seminar 2019
PPT
Rectal Cancer
PPTX
Carcinoma rectum - journal club
PPT
RECTUM CANCER MANAGEMENT
PPTX
Colorectal cancer
PPTX
Carcinoma rectum the complete aproach to how to investigate and treat a case ...
approach for rectal carcinoma and management
St gallen rectal carcinoma
Staging and Diagnostic approach of rectal cancer
final final recRectal carcinoma ca.pptx
Imaging in MRI of rectal carcinoma .pptx
the-multimodal-management-of-locally-advanced-rectal-cancer-making-sense-o.pdf
Rectal cancer
Carcinoma rectum
Recent Advances in Radiation Therapy for Rectal Cancer.pptx
Rectal carcinoma approach
Rectal cancer MRI (for staging of CA rectum), Dr. Adnan Rashid, MD
Management of Rectal cancer.pptx
Highlights in the treatment of Rectal cancer.pptx
MCC 2011 - Slide 2
Ca rectum Management seminar 2019
Rectal Cancer
Carcinoma rectum - journal club
RECTUM CANCER MANAGEMENT
Colorectal cancer
Carcinoma rectum the complete aproach to how to investigate and treat a case ...

More from Health Sciences North | Horizon Santé Nord (14)

PPTX
Questions to Ask Your Care Provider - Patient Safety
PDF
Alcohol Use Among Post Secondary Students
PPTX
End of Life Public Forum 2 - Dr. Andrew Knight - Feb. 6, 2014
PPTX
End of Life Public Forum 2 - Sr. Costanza Romano - Feb.6, 2014
PPT
End of Life Public Forum 2 - Lise Poratto Mason - Feb.6, 2014
PPT
End of Life Public Forum 2 - Frankie Vitone - Feb. 6, 2014
PPTX
End of Life From My Side of The Gurney | Dr. Brian Goldman
PPT
Dying, Dignity and Palliative End-of-Life Care | Dr. Harvey Chochinov
PPT
2013 Regional Oncology Conference: Closing Remarks, Mr. Mark Hartman
PPTX
Panel 1: Enhancing Access for Colorectal Cancer Screening and Diagnosis, Ms. ...
PPTX
Colorectal Cancer Disease Pathway Management, Northeast Ontario Context, Dr. ...
PPT
Genetics and Genomics in Cancer 2013: How Genomics is Changing Cancer Care, D...
PPTX
Designing a More Seniors-friendly Health Care System
PDF
Community Notice: Temporary Helipad
Questions to Ask Your Care Provider - Patient Safety
Alcohol Use Among Post Secondary Students
End of Life Public Forum 2 - Dr. Andrew Knight - Feb. 6, 2014
End of Life Public Forum 2 - Sr. Costanza Romano - Feb.6, 2014
End of Life Public Forum 2 - Lise Poratto Mason - Feb.6, 2014
End of Life Public Forum 2 - Frankie Vitone - Feb. 6, 2014
End of Life From My Side of The Gurney | Dr. Brian Goldman
Dying, Dignity and Palliative End-of-Life Care | Dr. Harvey Chochinov
2013 Regional Oncology Conference: Closing Remarks, Mr. Mark Hartman
Panel 1: Enhancing Access for Colorectal Cancer Screening and Diagnosis, Ms. ...
Colorectal Cancer Disease Pathway Management, Northeast Ontario Context, Dr. ...
Genetics and Genomics in Cancer 2013: How Genomics is Changing Cancer Care, D...
Designing a More Seniors-friendly Health Care System
Community Notice: Temporary Helipad

Recently uploaded (20)

PPTX
Indications for Surgical Delivery...pptx
PPTX
Phamacology Presentation (Anti cance drugs).pptx
PDF
Biochemistry And Nutrition For Bsc (Nursing).pdf
PDF
communicable diseases for healthcare - Part 1.pdf
PPTX
RESEARCH APPROACH & DESIGN.pptx presented by preeti kulshrestha
PDF
Cranial nerve palsies (I-XII) - AMBOSS.pdf
PPTX
SUMMARY OF EAR, NOSE AND THROAT DISORDERS INCLUDING DEFINITION, CAUSES, CLINI...
PDF
Gonadotropin-releasing hormone agonist versus HCG for oocyte triggering in an...
PPTX
ANTI BIOTICS. SULPHONAMIDES,QUINOLONES.pptx
PPTX
Surgical anatomy, physiology and procedures of esophagus.pptx
PPTX
Local Anesthesia Local Anesthesia Local Anesthesia
PDF
NCCN CANCER TESTICULAR 2024 ...............................
PDF
Tackling Intensified Climatic Civil and Meteorological Aviation Weather Chall...
PDF
periodontaldiseasesandtreatments-200626195738.pdf
PPTX
Communicating with the FDA During an Inspection -August 26, 2025 - GMP.pptx
PPTX
PSYCHIATRIC SEQUALAE OF HEAD INJURY.pptx
PDF
neonatology-for-nurses.pdfggghjjkkkkkkjhhg
PPTX
Geriatrics_(0).pptxxvvbbbbbbbnnnnnnnnnnk
PPTX
FORENSIC MEDICINE and branches of forensic medicine.pptx
PPTX
ENT-DISORDERS ( ent for nursing ). (1).p
Indications for Surgical Delivery...pptx
Phamacology Presentation (Anti cance drugs).pptx
Biochemistry And Nutrition For Bsc (Nursing).pdf
communicable diseases for healthcare - Part 1.pdf
RESEARCH APPROACH & DESIGN.pptx presented by preeti kulshrestha
Cranial nerve palsies (I-XII) - AMBOSS.pdf
SUMMARY OF EAR, NOSE AND THROAT DISORDERS INCLUDING DEFINITION, CAUSES, CLINI...
Gonadotropin-releasing hormone agonist versus HCG for oocyte triggering in an...
ANTI BIOTICS. SULPHONAMIDES,QUINOLONES.pptx
Surgical anatomy, physiology and procedures of esophagus.pptx
Local Anesthesia Local Anesthesia Local Anesthesia
NCCN CANCER TESTICULAR 2024 ...............................
Tackling Intensified Climatic Civil and Meteorological Aviation Weather Chall...
periodontaldiseasesandtreatments-200626195738.pdf
Communicating with the FDA During an Inspection -August 26, 2025 - GMP.pptx
PSYCHIATRIC SEQUALAE OF HEAD INJURY.pptx
neonatology-for-nurses.pdfggghjjkkkkkkjhhg
Geriatrics_(0).pptxxvvbbbbbbbnnnnnnnnnnk
FORENSIC MEDICINE and branches of forensic medicine.pptx
ENT-DISORDERS ( ent for nursing ). (1).p

Panel 2: Optimizing Integrated Colorectal Cancer Treatment Planning and Patient Support, Dr. Michael Loreto, Ms. Kathleen Callaghan, Ms. Julie Whitten, Ms. Traci Franklin

  • 1. Panel 2: Optimizing Integrated Colorectal Cancer Treatment Planning and Patient Support Panelists: Michael Loreto MD FRCP(C) Kathleen Callaghan BSC RN ET Julie Whitten BSc RD Traci Franklin MSW RSW
  • 2. Mr. TW: Case History 2 • Colonoscopy reveals a rectal cancer • A rectal MRI for pre-operative staging reveals Stage III rectal cancer • Pre-operative chemo-radiotherapy, then a total mesorectal excision followed by postoperative chemotherapy • Mr. TW has a temporary colostomy, has bowel habit changes and feels depressed
  • 3. Role of MRI in Staging and Treatment Decisions for Patients with Rectal Cancer Dr. Michael Loreto Associate Radiologist, Health Sciences North
  • 4. Which patients benefit from a pre-operative MRI? ALL patients with rectal cancer should have a pre-operative MRI as hi-resolution MRI has become the diagnostic standard for the accurate LOCAL STAGING of rectal cancer.
  • 5. What information does a preoperative MRI provide? • Local staging – primary tumour (T-stage) – regional lymph nodes (N)
  • 6. Assessment of the Primary Tumour – T-stage Modified TNM Staging (AJCC)
  • 7. StageT2 Hi-res T2-weighted axial (short-axis) image Kaur H et al. RadioGraphics (2012)
  • 8. “early stage” T3 Kaur H et al. RadioGraphics (2012) “advanced stage” T3
  • 9. How does rectal MRI influence treatment decisions? • Identification of patients who may benefit from preoperative chemoradiation • Surgical planning
  • 10. Neo-adjuvant Treatment • Current Cancer Care Ontario (CCO) guidelines: – Pre-operative chemoradiation for stage II (T3-T4N0) and stage III (T1-4N1-2) primary rectal cancer • Recommendations based on multiple RCTs showing that pre-op RT and pre-op CRT significantly reduce the risk of local recurrence
  • 11. Low Rectal Cancers • Lower extent between 0 – 5 cm from the anal verge • Lower extent above the top border of the puborectalis may be amenable to sphinctersparing surgery • Lower extent at or below the top border of the puborectalis will require abdominal perineal resection (T1 and early T2), extralevator APR (advanced T2 and T3) or pelvic exenteration (T4)
  • 12. CCO Synoptic Report for Rectal Cancer • In an attempt to standardize reporting, CCO has developed an evidence-based synoptic report template that radiologists have been encouraged to utilize • Report template includes important rectal tumour characteristics that influence neo-adjuvant and surgical treatment decisions
  • 13. How are rectal cancer treatment decisions made at HSN? • Rectal cancer cases are discussed at multidisciplinary case conferences (MCC) on a weekly basis • Imaging is reviewed by the radiologist, and treatment decisions are discussed amongst the attending medical oncologists, radiation oncologists and surgeons
  • 14. Summary • Rectal MRI is the diagnostic standard for local staging of primary rectal cancer • CCO has created an evidence-based synoptic report emphasizing key findings to help identify patients requiring neo-adjuvant treatment and to assist surgeons in determining the type/extent of surgery required • Multidisciplinary case conferences at HSN ensure that proper discussion occurs between radiologists, oncologists and surgeons prior to a treatment plan being implemented
  • 15. References 1. Taylor FGM et al. A Systematic Approach to the Interpretation of Preoperative Staging MRI for Rectal Cancer. AJR: 191; pp.1827-1835 (2008). 2. Kaur H et al. MRI Imaging for Preoperative Evaluation of Primary Rectal Cancer: Practical Considerations. RadioGraphics: 32; pp.389-409 (2012). 3. Cancer Care Ontario User’s Guide for the Synoptic MRI Report for Rectal Cancer (https://www.cancercare.on.ca).
  • 16. Role of the Enterostomal Therapist Kathleen Callaghan BScN RN ET Enterostomal Therapist Nurse Continence Advisor, HSN
  • 17. Nutrition Intervention During Rectal Cancer Treatment Julie Whitten, B.Sc., RD Supportive Care Program Northeast Cancer Centre, HSN
  • 18. Nutrition Intervention During Rectal Cancer Treatment • Automatic nutrition referral • Monitor bowel function and nutritional status throughout treatment
  • 20. Nutrition Interventions • Low Roughage, Low Fibre Diet – Avoid insoluble fibre – Focus on soluble fibre • Fluid intake – – – – Increased fluid needs Avoid hyper-osmotic fluids (fruit drinks, sodas) Oral rehydration solutions Parenteral hydration • Limit caffeine, alcohol, fried/greasy foods, carbonated beverages • Small, frequent meals at regular times
  • 22. Psychosocial Care for Colorectal Cancer Traci Franklin MSW RSW Supportive Care Program Northeast Cancer Centre, HSN
  • 24. Depression in Cancer • • • • Mood Affect Thoughts: hopeless, helpless Fears: – Disability, loss of roles, disfigurement, loss of control, loss of support, dying, pain – Feeling they are being punished
  • 25. Depression in Cancer • The prevalence of significant emotional distress, defined as anxiety, depression, and adjustment disorders, ranges from 35% to 45% across studies in North America (Carlson & Bultz, 2003; Zabora, Brintzenhofeszoc, Curbow, Hooker & Piantadosi, 2001)
  • 26. Psychosocial Factors  Sexual Dysfunction  pelvic surgery, radiotherapy  Body Image  colostomy  Relational Adjustment  Anxiety about bowel incontinence  Financial Concerns  Cost of supplies  Coping with Side effects of Treatment