Pits and fissures are enamel faults such as depressions or cracks that are vulnerable to dental caries. Fissure sealants are materials placed in pits and fissures to prevent caries. They have evolved from early dental cements to modern resin-based sealants cured with light. Sealants are indicated for teeth with deep fissures and those opposite teeth with caries. The procedure involves isolating and drying the tooth before applying the sealant. Preventive resin restorations integrate sealants with restorative resin to treat early caries in fissures.