Late blight of potato in Ireland from 1845-1860, powdery and downy mildew of grape in France in 1851 and 1878, and coffee rust in Ceylon starting in the 1870s were some of the major plant disease outbreaks mentioned. Loss of crops from plant diseases can result in hunger, especially in less developed countries where annual losses of 30-50% are common. Major disease outbreaks have led to famines and mass migrations throughout history, such as the Irish potato famine caused by late blight that resulted in starvation, death, and mass Irish migration.