Positioning involves placing a patient in specific body alignments to promote health and allow for medical interventions. Some key reasons for positioning include providing comfort, relieving pressure on body parts, improving circulation, preventing deformities, and enabling examinations and treatments. Common positions include supine, prone, lateral, lithotomy and Fowler's positions, each having distinct uses and safety considerations. Positioning requires ensuring patient comfort and safety by using supportive devices and regularly adjusting alignment to prevent pressure injuries.