This document provides guidance on selecting and using personal protective equipment (PPE) in healthcare settings. It outlines the goals of a PPE program which are to improve safety through appropriate PPE use. It defines PPE and outlines regulations and recommendations from OSHA and CDC on PPE use. The document describes different types of PPE like gloves, gowns, masks, goggles and respirators and provides details on proper donning, use and removal to prevent exposure to infectious materials.