Introduction
CLABSI (centralline associated blood-
stream infection)is the most serious HAI.
It is preventable through complete
adherence to aseptic protocols, surveillance,
and management measures
4.
Definition
1. CLABSI isa laboratory confirmed
bloodstream infection in which central line
is in place within 48 hours before the
development of the bloodstream infection
–haddadin and ragunath, 2017
Risk factor
Immunocompromisedstate- Neutrogena, diabetes
mellitus, and bone marrow transplant or organ
transplant recipient
Prolonged hospitalization before catheter insertion
Total parental nutrition and dialysis
Chronic illness
Extremes of age
Burns and other skin pathology
8.
Pathophysiology
Breach in asepticprecaution at the time of insertion
Hub contamination through Breach in aseptic handling
of catheter
Infusing contaminated fluids
Migration of organism from the contaminated skin
through the exit point of the lumen of catheter
Pus ordrainage around exit site
Redness, induration, and swelling at
insertion site
Pain
Poor or no return blood flow from venous
access
11.
Management
After takingblood culture, empirical
antibiotic therapy may be started
On receiving culture report based on the
sensitivity, systemic antibiotic therapy
should be started and may be given for 2
week duration
If CLABSI is proven, the catheter can be
removed and tip sent for culture and
sensitivity
Cont…
12.
In hemodialysis, topicaland systemic
antibiotic therapy may be initially attempted
In case of tunneled catheter getting infected,
it needs to be removed
13.
Prevention
The societyfor health care epidemiology of
America and infectious diseases society of
America (SHEA / IDSA) guidelines are give
as follows :
• CLABSI/ CRBSIprevention:
At the time of central line insertion
Perform hand hygiene with soap and water of foam
or alcohol-based gels
Ensure adherence to infection control protocol
while central line insertion using a checklist
Use of gloves does not prevent hand hygiene
Avoid using the femoral vein for central venous
access in obese adult patients
Do not use peripheral inserted CVCs as a strategy
to reduce risk of CLABSI
Cont…
16.
Use maximumsterile barrier precautions
during CVC insertion, which include wearing
sterile PPE and draping the whole body with a
large sterile sheet
For smooth complication-free internal jugular
catheter insertion, use ultrasound guidance
Apply an alcohol based or chlorhexidine
antiseptic solution for skin preparation before
puncture
17.
Maintain appropriatenurse-patient ratio
Before touching the patient and the central venous
access, perform hand hygiene
Catheter hubs, needleless connectors, and injection
ports need to be disinfected by using sterile swab and
70 % alcohol or providing-iodine /chlorhexidine based
solution before accessing the central line
Apply mechanical friction for no less than 5 seconds
before touching any part of tubing hubs or connectors
or ports to reduce contamination
• CLABSI/ CRBSI prevention:
Catheter maintenance bundle
Cont…
18.
Use centralvascular access to the period
most necessary.
Remove unwanted extension catheters.
Regularly assess the need for central venous
access and if not accessory remove it at the
earliest.
For non tunneled catheter, change the soiled
dressing at once, if there is gauze dressing,
change the dressing with all aseptic
precautions once in 2 days. In case of
transparent dressing, it can be changed once
in 5 to 7 days time.
19.
Blood sets haveto changed in 24 hours time.
Iv sets used for infusing lipid emulsion,
propofol, need to be changed in 12 hours time .
Iv lines can be changed at least within 96
hours.
Use antimicrobial locks.
What isthe full form of CLABSI ?
what signs and symptoms will
occur after CLABSI ?
Which are two key times to
prevent CLABSI ?
QNA
24.
Bibliography
Suresh k.sharma and s. Madhavi.brunner
and suddharth’s medical surgical
nursing.south Asian edition.volume
2 .published by Wolters kluwer .Delhi.pg no.
2149-2150
Anju dhir .textbook of applied microbiology
including infection control and safety.2nd
edition. CBS publishers and distributors, pvt
Ltd.pg no. 341-344