Probabilistic and approximate data structures can provide scalable solutions when exact answers are not required. They trade accuracy for speed and efficiency. Approaches like sampling, hashing, cardinality estimation, and probabilistic databases allow analyzing large datasets while controlling error rates. Example techniques discussed include Bloom filters, locality-sensitive hashing, count-min sketches, HyperLogLog, and feature hashing for machine learning. The talk provided code examples and comparisons of these probabilistic methods.