The document proposes a new channel estimation algorithm called ICEA-DA for MIMO-OFDM systems. ICEA-DA uses least squares estimation with discrete Fourier transform and integrates it with a differential evolution technique. It is placed at the central part of the MIMO-OFDM system between the transmitter and receiver blocks. The proposed method is evaluated for a 2x4 MIMO system using QPSK modulation. Results show ICEA-DA provides better performance than existing techniques in terms of bit error rate, peak signal-to-noise ratio, channel capacity, and symbol error rate.