This document outlines the key principles of a science curriculum framework for basic education in the Philippines. The framework is designed to guide the development of instructional materials and learning experiences to help students become scientifically literate. It covers three components: inquiry skills, scientific attitudes, and science content and connections. The content is organized around enduring understandings and essential questions within the domains of life science, physical science, and earth and space science. The framework emphasizes developing both content knowledge and process skills through relevant, applied learning experiences.