- A sequestrum is a separated, necrotic fragment of bone surrounded by infected tissue and pus. It acts as a nidus for bacteria to thrive.
- Sequestra come in different shapes, sizes, colors and consistencies depending on the underlying condition. Common types include pencil-like in infants and cylindrical in tuberculosis.
- Identifying sequestra involves injecting dyes like methylene blue which will stain live bone gray but leave dead bone blue. Removal of sequestra via sequestrectomy eliminates the infection and aids healing.
- Conditions that can mimic sequestra on imaging include radiation necrosis, bone tumors and mineralization of other lesions.