Sixth Sense technology, developed by Steve Mann and enhanced by Pranav Mistry at MIT Media Lab, integrates digital information into the physical world through a wearable device that combines a camera, projector, and mobile computing. It allows users to interact with their environment using hand gestures, turning any surface into a touch-screen for accessing information and applications. Despite its potential for various uses, the technology has limitations like dependency on specific operating systems and visibility issues in bright environments.