Technology
in Medicine
I
By : Khaled H. Alkhodari
Supervisor : Dr. Jehad H. Hammad
Contents
• Introduction
• Operating Systems
• Apps:
– BNF 69
– DynaMed
– Medscape
– ٌ‫دواء‬
• Databases:
– Hinari
– EBSCO-DynaMed
– Others
Technology in medicine
Technology in medicine
In late 2010, Microsoft executive Stephen Elop became
CEO at the then independent smartphone-maker Nokia.
He concluded that
Nokia's persistence in keeping its own smartphone platform,
Symbian, was a mistake
— he compared its strategy to a "burning platform" in a
memo in February 2011.
Technology in medicine
Technology in medicine
Technology in medicine
Technology in medicine
Technology in medicine
Technology in medicine
Technology in medicine
Technology in medicine
Technology in medicine
Technology in medicine
Technology in medicine
Technology in medicine
Technology in medicine
Use them WELL
Visual
Reality
Technology in medicine
Are MMA included in research?
Technology in medicine
• Alzheimer disease : GPS
• Using smartphones connected via Bluetooth to a
single-lead electrocardiograph (ECG) device.
• Stroke: accelerometer can be used to interpret gait
and balance of patients.
AliveCor Mobile ECG 113$
715$
Technology in medicine
• DM1 Pt.:A self-adjusting insulin calculator ,digital diary
for long and short-acting insulin doses based on their
doctor’s prescription, tailored to nutritional intake and
physical activity.
• sleep apnea:single-lead ECGproviding a possible
alternative to costly and labor-intensive
polysomnography
Technology in medicine
Technology in medicine
A study in 2010 claimed that >60%
of physicians surveyed felt that
Epocrates helped to reduce medical
errors
Technology in medicine
Percentage frequency of use of
different categories of medical apps
within the junior doctor group
Percentage frequency of use of different
categories of medical apps within the
medical student group
Technology in medicine
Technology in medicine
• UpToDate
– an evidence-based clinical smartphone tool
– provides the most recent clinical evidence and includes
more than 9,000 physicians’ topics, 5,000 drug topics,
practice change updates, etc.
– This application is very useful in the practice of EBM at the
bedside
– is very useful for the integration of test results with
clinical information
• six applications providing common laboratory test
information including reference values and
interpretation, causes for abnormal (increased or
decreased) values, and laboratory unit conversions.
– Palm LabDX,
– Normal Lab Values,
– Lab Unit Converter,
– Labs 360o,
– Davis’s Laboratory and Diagnostic Tests,
– Pocket Guide to Diagnostic Tests
• Smartphones can also be applied in the process of
diagnosis and treatment using software application.
• A simple smartphone application for eye-care
professionals is a visual acuity test.
– EyeChart is an iPhone application that includes the
Snellen eye chart to measure visual acuity
– A similar application is EyePhone, which includes a
distance E-test, near visual acuity test, color test, Amsler
grid, and pupil gauge test
Drug Reference Applications
• six applications are: Skyscape’s RxDrugs, Epocrates,
Medscape, SafeMed Pocket, FDA drugs, and DrugDoses.net.
• Epocrates was cited as the most common
• Epocrates and Skyscape’s RxDrugs, another drug reference
can check multiple drug-drug interaction at the same time
• FDA Drugs, which includes package inserts or official labels of
FDA-approved prescription and over-the-counter drugs,
shares this functionality and also searches by active
ingredients
Number of Healthcare Applications per OS Platform Discussed in this Study
Technology in medicine
Technology in medicine
Technology in medicine
Technology in medicine
Examples of MMAs the FDA regulates
1. Mobile apps that use a sensor or to measure and display ECG
2. apps that use a sensor attached to the mobile or in it (e.g.,
microphone and speaker) to electronically amplify sounds
associated with the heart, arteries and veins and other internal
organs (i.e., an electronic stethoscope)
3. Apps measure physiological parameters during
cardiopulmonary resuscitation (CPR) and give feedback about
the quality of CPR being delivered.
4. Apps record, view, or analyze eye movements for use in the
diagnosis of balance disorders (i.e., nystagmograph).
5. App produce controlled levels of test tones and signals
intended for use in conducting diagnostic hearing evaluations
and assisting in the diagnosis of possible otologic disorders
(i.e., an audiometer)
6. Measure the degree of tremor caused by certain diseases (i.E.,
A tremor transducer).
7. Measure physiological parameters (e.G., Limb movement,
electrical activity of the brain (EEG)) during sleep and are
intended for use in diagnosis of specific diseases or conditions
such as sleep apnea.
8. Measure blood oxygen saturation for diagnosis of specific
disease or condition.
9. Potential blood donor and record and/or transmit the
responses to those questions for a blood collection facility to
use in determining blood donor eligibility prior to collection of
blood or blood components
10. Measure blood glucose levels
11. To treat acne, reduce wrinkles, or remove hair
12. Audiometer to allow healthcare providers to determine
hearing loss at different frequencies.
13. Analyze an image of a skin lesion using mathematical
algorithms, such as fractal analysis, and provide the user
with an assessment of the risk of the lesion
14. Alter the function or settings of an infusion pump.
15. Control or change settings of an implantable
neuromuscular stimulator
16. Calibrate, control, or change settings of a cochlear implant.
17. Control the inflation or deflation of a blood-pressure cuff.
18. Calibrate hearing aids and assess the electroacoustic
frequency and sound intensity
19. Mobile apps that connect to a nursing central station and
display medical device data to a physician’s mobile platform for
review
20. Mobile apps that connect to bedside (or cardiac) monitors and
transfer the data to a central viewing station for display and
active patient monitoring.
21. Mobile apps that connect to a perinatal monitoring system
and transfer uterine contraction and fetal heart rate data to
another display to allow for remote monitoring of labor
progress.
22. Mobile apps that are intended to display images for diagnostic
review may be regulated as a picture archiving and
communications system
Technology in medicine
211 app nearly
Technology in medicine
Technology in medicine
Technology in medicine
Technology in medicine
79% android=31
18% IOS =7
1% others=1
Android IOS Others
Technology in medicine
Technology in medicine
Pharmacology in your pocket
instead of memorizing texts
BNF British National Formulary.
• New edition /6m (Mar-Sep)
• The first was on 1949 , Today 71th ed.
• BNF Publications are published jointly by the
– British Medical Association
– The Royal Pharmaceutical Society.
• They are independent resources that do not market
medicines.
• Content includes:
– Guidance on the drug management of common conditions.
– Details of medicines with special reference to their uses, cautions,
contra-indications, side-effects, doses, and relative costs.
– Guidance on prescribing, monitoring, dispensing, and
administering medicines.
Sources
• Summaries of product characteristics (SPCs). The principal.
• Expert advisers.
• Medical and pharmaceutical journals, research papers …
• Systematic reviews databases eg Cochrane.
• Reference sources such as Martindale: The Complete Drug
Reference.
• Pricing information. Provided by the NHS Prescription
Services (from the NHS Business Services Authority).
Martindale: The Complete Drug Reference 38th ed. 2014
• This package contains two hardback volumes (4688pages)
presented in a slipcase with:
– Over 6,000 (and over 7,000 online) drug monographs
– Over 180,000 (and over 240,000 online) preparations
– Over 54,000 reference citations
– About 20,000 (and 25,000 online) manufacturers and distributors
– Proprietary preparations from 43 countries and regions
– Nearly 700 disease reviews, with references from the published
literature
– Information to enable identification of medicines, the local equivalent
and the manufacturer
– Herbals, diagnostic agents, radiopharmaceuticals, pharmaceutical
excipients, toxins, and poisons as well as drugs and medicines.
publication
Technology in medicine
Technology in medicine
Technology in medicine
Technology in medicine
Technology in medicine
Technology in medicine
Technology in medicine
Technology in medicine
For
topics
in your
search
Technology in medicine
Any thing Blue , you can click
on it and read more
Always updated
Technology in medicine
Technology in medicine
Technology in medicine
Medscape
• Medscape is a web resource for physicians and health
professionals.
• It features:
– peer-reviewed original medical journal articles,
– CME (continuing medical education)
– A customized version of the national library of medicine's
MEDLINE database
– Daily medical news
– Major conference coverage
– Drug information—including a drug database (medscape
drug reference, or MDR) and drug interaction checker
For
latest
news
For
Continuing
medical
eduction
(CME)
Technology in medicine
Technology in medicine
Palestinian Ministry of health
& ministry of IT
Technology in medicine
$$$$$$$$$
So What !!
Technology in medicine
IUG Databases
Islamic University of Gaza (IUG)
Technology in medicine
Technology in medicine
Technology in medicine
• Set up by WHO together with major publishers.
• Enables low- and middle- income countries to gain
access to one of the world's largest collections of
biomedical and health literature:
– Up to 15,000 journals (in 30 different languages).
– Up to 47,000 e-books
– Up to 100 other information resources
– Now available to health institutions in more than 100
countries
Video
Technology in medicine
Technology in medicine
Technology in medicine
Technology in medicine
Technology in medicine
Technology in medicine
Technology in medicine
Did you see this?
Level 1 (likely reliable)
Representing research results addressing clinical outcomes and
meeting an extensive set of quality criteria which minimizes bias.
Level 3 (lacking direct) Evidence
Representing research results addressing clinical outcomes, and
using some method of scientific investigation, but not meeting the
quality criteria to achieve level 1 evidence labeling.
Level 2 (mid-level) Evidence
Representing reports that are not based on scientific analysis
of clinical outcomes.
Examples include case series, case reports,
expert opinion, and conclusions extrapolated
indirectly from scientific studies.
1
EBM Journal
EBM Focus
The EBM Focus is a free weekly e-newsletter providing a
concise summary of articles most likely to inform clinical
practice.
Resident Focus
The Resident Focus is a free e-newsletter written by medical
residents highlighting recent clinical evidence they find
important at the point-of-care.
Archives
Read past issues of the EBM Focus, Resident Focus
Technology in medicine
Recent Updates
E- Newsletter
Calculators
Technology in medicine
Technology in medicine
Technology in medicine
Did you see this?
2
3
4
Technology in medicine
`
Technology in medicine
Technology in medicine
• Cambridge Journals
1. Brain Impairment
2. Breast Cancer Online
3. British Journal of Anaesthetic
and Recovery Nursing
4. Cambridge Quarterly of
Healthcare Ethics
5. Canadian Journal of
Emergency Medicine
6. Cardiology in the Young
7. Developmental Medicine &
Child Neurology
8. Disaster Medicine and Public
Health Preparedness
9. European Journal of
Anaesthesiology
10. Expert Reviews in Molecular
Medicine
11. Fetal and Maternal Medicine
Review
12. Global Health, Epidemiology
13. Health Economics, Policy
and Law
14. Infection Control &
Hospital Epidemiology
(formerly Infection Control
Volumes 1 (1980) - 8
(1987))
15. International Journal of
Disability Management
16. International Journal of
Technology Assessment in
Health Care
17. Journal of Dentofacial
Anomalies and
Orthodontics
18. Journal of Diagnostic
Radiography and Imaging
19. The Journal of
Laryngology & Otology
(formerly The Journal of
Laryngology, Rhinology,
and Otology Volumes 6
(1892) - 35 (1920), The
Journal of Laryngology and
20. Journal of
Psychiatric
Intensive Care
21. Journal of
Radiotherapy in
Practice
22. Nurse Prescriber
23. Palliative &
Supportive Care
24. Prehospital and
Disaster Medicine
(formerly Journal
of the World
Association for
Emergency and
Disaster Medicine
Volumes 1 (1985) -
3 (1987).)
25. Primary Health
Care Research &
Development
26. Reviews in Clinical
Gerontology
Technology in medicine
Technology in medicine
some Members of the OpenAthens Federation
include:
https://auth.athensams.net/list_orgs.php
1. AkzoNobel
2. American Medical
Association
3. Cambridge University Press
4. Cengage Learning
5. Department of Health
(Victoria, Australia)
6. Department of Veterans
Affairs (USA)
7. EBSCO
8. Elsevier
9. Emerald Group Publishing
10. IEEE
11. Informa Healthcare
12. Ingram Digital
Ltd/MyiLibrary
13. John Wiley & Sons
14. JSTOR
15. LexisNexis
16. Maney Publishing
17. McGraw Hill Professional
18. National Institute for
Health and Clinical
Excellence (NICE) on behalf
of NHS organisations in
England
19. Nature Publishing Group
20. New England Journal of
Medicine
21. Navy Medicine Information
Systems Support Agency
(NAVMISSA)
22. NHS Scotland
23. NHS Wales
24. Oxford University Press
25. Philips Research
26. ProQuest
27. Royal Australia and New
Zealand College of
28. Ophthalmologists
29. Royal Dutch Shell
30. SAGE Publications
31. Springer
32. Taylor & Francis
33. Thieme
34. Thomson Healthcare
35. Thomson Scientific
36. U.S. Army Medical
Department (AMEDD)
37. U.S. Army Research
Institute
38. US Department of
Defense
39. Westlaw
40. Wolters Kluwer Health
Technology in medicine
The End of Part #1

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Technology in medicine

  • 1. Technology in Medicine I By : Khaled H. Alkhodari Supervisor : Dr. Jehad H. Hammad
  • 2. Contents • Introduction • Operating Systems • Apps: – BNF 69 – DynaMed – Medscape – ٌ‫دواء‬ • Databases: – Hinari – EBSCO-DynaMed – Others
  • 5. In late 2010, Microsoft executive Stephen Elop became CEO at the then independent smartphone-maker Nokia. He concluded that Nokia's persistence in keeping its own smartphone platform, Symbian, was a mistake — he compared its strategy to a "burning platform" in a memo in February 2011.
  • 22. Are MMA included in research?
  • 24. • Alzheimer disease : GPS • Using smartphones connected via Bluetooth to a single-lead electrocardiograph (ECG) device. • Stroke: accelerometer can be used to interpret gait and balance of patients. AliveCor Mobile ECG 113$ 715$
  • 26. • DM1 Pt.:A self-adjusting insulin calculator ,digital diary for long and short-acting insulin doses based on their doctor’s prescription, tailored to nutritional intake and physical activity. • sleep apnea:single-lead ECGproviding a possible alternative to costly and labor-intensive polysomnography
  • 29. A study in 2010 claimed that >60% of physicians surveyed felt that Epocrates helped to reduce medical errors
  • 31. Percentage frequency of use of different categories of medical apps within the junior doctor group Percentage frequency of use of different categories of medical apps within the medical student group
  • 34. • UpToDate – an evidence-based clinical smartphone tool – provides the most recent clinical evidence and includes more than 9,000 physicians’ topics, 5,000 drug topics, practice change updates, etc. – This application is very useful in the practice of EBM at the bedside – is very useful for the integration of test results with clinical information
  • 35. • six applications providing common laboratory test information including reference values and interpretation, causes for abnormal (increased or decreased) values, and laboratory unit conversions. – Palm LabDX, – Normal Lab Values, – Lab Unit Converter, – Labs 360o, – Davis’s Laboratory and Diagnostic Tests, – Pocket Guide to Diagnostic Tests
  • 36. • Smartphones can also be applied in the process of diagnosis and treatment using software application. • A simple smartphone application for eye-care professionals is a visual acuity test. – EyeChart is an iPhone application that includes the Snellen eye chart to measure visual acuity – A similar application is EyePhone, which includes a distance E-test, near visual acuity test, color test, Amsler grid, and pupil gauge test
  • 37. Drug Reference Applications • six applications are: Skyscape’s RxDrugs, Epocrates, Medscape, SafeMed Pocket, FDA drugs, and DrugDoses.net. • Epocrates was cited as the most common • Epocrates and Skyscape’s RxDrugs, another drug reference can check multiple drug-drug interaction at the same time • FDA Drugs, which includes package inserts or official labels of FDA-approved prescription and over-the-counter drugs, shares this functionality and also searches by active ingredients
  • 38. Number of Healthcare Applications per OS Platform Discussed in this Study
  • 43. Examples of MMAs the FDA regulates 1. Mobile apps that use a sensor or to measure and display ECG 2. apps that use a sensor attached to the mobile or in it (e.g., microphone and speaker) to electronically amplify sounds associated with the heart, arteries and veins and other internal organs (i.e., an electronic stethoscope) 3. Apps measure physiological parameters during cardiopulmonary resuscitation (CPR) and give feedback about the quality of CPR being delivered. 4. Apps record, view, or analyze eye movements for use in the diagnosis of balance disorders (i.e., nystagmograph). 5. App produce controlled levels of test tones and signals intended for use in conducting diagnostic hearing evaluations and assisting in the diagnosis of possible otologic disorders (i.e., an audiometer)
  • 44. 6. Measure the degree of tremor caused by certain diseases (i.E., A tremor transducer). 7. Measure physiological parameters (e.G., Limb movement, electrical activity of the brain (EEG)) during sleep and are intended for use in diagnosis of specific diseases or conditions such as sleep apnea. 8. Measure blood oxygen saturation for diagnosis of specific disease or condition. 9. Potential blood donor and record and/or transmit the responses to those questions for a blood collection facility to use in determining blood donor eligibility prior to collection of blood or blood components 10. Measure blood glucose levels 11. To treat acne, reduce wrinkles, or remove hair
  • 45. 12. Audiometer to allow healthcare providers to determine hearing loss at different frequencies. 13. Analyze an image of a skin lesion using mathematical algorithms, such as fractal analysis, and provide the user with an assessment of the risk of the lesion 14. Alter the function or settings of an infusion pump. 15. Control or change settings of an implantable neuromuscular stimulator 16. Calibrate, control, or change settings of a cochlear implant. 17. Control the inflation or deflation of a blood-pressure cuff. 18. Calibrate hearing aids and assess the electroacoustic frequency and sound intensity
  • 46. 19. Mobile apps that connect to a nursing central station and display medical device data to a physician’s mobile platform for review 20. Mobile apps that connect to bedside (or cardiac) monitors and transfer the data to a central viewing station for display and active patient monitoring. 21. Mobile apps that connect to a perinatal monitoring system and transfer uterine contraction and fetal heart rate data to another display to allow for remote monitoring of labor progress. 22. Mobile apps that are intended to display images for diagnostic review may be regulated as a picture archiving and communications system
  • 53. 79% android=31 18% IOS =7 1% others=1 Android IOS Others
  • 56. Pharmacology in your pocket instead of memorizing texts
  • 57. BNF British National Formulary. • New edition /6m (Mar-Sep) • The first was on 1949 , Today 71th ed. • BNF Publications are published jointly by the – British Medical Association – The Royal Pharmaceutical Society. • They are independent resources that do not market medicines. • Content includes: – Guidance on the drug management of common conditions. – Details of medicines with special reference to their uses, cautions, contra-indications, side-effects, doses, and relative costs. – Guidance on prescribing, monitoring, dispensing, and administering medicines.
  • 58. Sources • Summaries of product characteristics (SPCs). The principal. • Expert advisers. • Medical and pharmaceutical journals, research papers … • Systematic reviews databases eg Cochrane. • Reference sources such as Martindale: The Complete Drug Reference. • Pricing information. Provided by the NHS Prescription Services (from the NHS Business Services Authority).
  • 59. Martindale: The Complete Drug Reference 38th ed. 2014 • This package contains two hardback volumes (4688pages) presented in a slipcase with: – Over 6,000 (and over 7,000 online) drug monographs – Over 180,000 (and over 240,000 online) preparations – Over 54,000 reference citations – About 20,000 (and 25,000 online) manufacturers and distributors – Proprietary preparations from 43 countries and regions – Nearly 700 disease reviews, with references from the published literature – Information to enable identification of medicines, the local equivalent and the manufacturer – Herbals, diagnostic agents, radiopharmaceuticals, pharmaceutical excipients, toxins, and poisons as well as drugs and medicines.
  • 71. Any thing Blue , you can click on it and read more
  • 76. Medscape • Medscape is a web resource for physicians and health professionals. • It features: – peer-reviewed original medical journal articles, – CME (continuing medical education) – A customized version of the national library of medicine's MEDLINE database – Daily medical news – Major conference coverage – Drug information—including a drug database (medscape drug reference, or MDR) and drug interaction checker
  • 80. Palestinian Ministry of health & ministry of IT
  • 88. • Set up by WHO together with major publishers. • Enables low- and middle- income countries to gain access to one of the world's largest collections of biomedical and health literature: – Up to 15,000 journals (in 30 different languages). – Up to 47,000 e-books – Up to 100 other information resources – Now available to health institutions in more than 100 countries
  • 89. Video
  • 97. Did you see this?
  • 98. Level 1 (likely reliable) Representing research results addressing clinical outcomes and meeting an extensive set of quality criteria which minimizes bias. Level 3 (lacking direct) Evidence Representing research results addressing clinical outcomes, and using some method of scientific investigation, but not meeting the quality criteria to achieve level 1 evidence labeling. Level 2 (mid-level) Evidence Representing reports that are not based on scientific analysis of clinical outcomes. Examples include case series, case reports, expert opinion, and conclusions extrapolated indirectly from scientific studies. 1
  • 99. EBM Journal EBM Focus The EBM Focus is a free weekly e-newsletter providing a concise summary of articles most likely to inform clinical practice. Resident Focus The Resident Focus is a free e-newsletter written by medical residents highlighting recent clinical evidence they find important at the point-of-care. Archives Read past issues of the EBM Focus, Resident Focus
  • 107. Did you see this?
  • 108. 2
  • 109. 3
  • 110. 4
  • 112. `
  • 115. • Cambridge Journals 1. Brain Impairment 2. Breast Cancer Online 3. British Journal of Anaesthetic and Recovery Nursing 4. Cambridge Quarterly of Healthcare Ethics 5. Canadian Journal of Emergency Medicine 6. Cardiology in the Young 7. Developmental Medicine & Child Neurology 8. Disaster Medicine and Public Health Preparedness 9. European Journal of Anaesthesiology 10. Expert Reviews in Molecular Medicine 11. Fetal and Maternal Medicine Review 12. Global Health, Epidemiology 13. Health Economics, Policy and Law 14. Infection Control & Hospital Epidemiology (formerly Infection Control Volumes 1 (1980) - 8 (1987)) 15. International Journal of Disability Management 16. International Journal of Technology Assessment in Health Care 17. Journal of Dentofacial Anomalies and Orthodontics 18. Journal of Diagnostic Radiography and Imaging 19. The Journal of Laryngology & Otology (formerly The Journal of Laryngology, Rhinology, and Otology Volumes 6 (1892) - 35 (1920), The Journal of Laryngology and 20. Journal of Psychiatric Intensive Care 21. Journal of Radiotherapy in Practice 22. Nurse Prescriber 23. Palliative & Supportive Care 24. Prehospital and Disaster Medicine (formerly Journal of the World Association for Emergency and Disaster Medicine Volumes 1 (1985) - 3 (1987).) 25. Primary Health Care Research & Development 26. Reviews in Clinical Gerontology
  • 118. some Members of the OpenAthens Federation include: https://auth.athensams.net/list_orgs.php 1. AkzoNobel 2. American Medical Association 3. Cambridge University Press 4. Cengage Learning 5. Department of Health (Victoria, Australia) 6. Department of Veterans Affairs (USA) 7. EBSCO 8. Elsevier 9. Emerald Group Publishing 10. IEEE 11. Informa Healthcare 12. Ingram Digital Ltd/MyiLibrary 13. John Wiley & Sons 14. JSTOR 15. LexisNexis 16. Maney Publishing 17. McGraw Hill Professional 18. National Institute for Health and Clinical Excellence (NICE) on behalf of NHS organisations in England 19. Nature Publishing Group 20. New England Journal of Medicine 21. Navy Medicine Information Systems Support Agency (NAVMISSA) 22. NHS Scotland 23. NHS Wales 24. Oxford University Press 25. Philips Research 26. ProQuest 27. Royal Australia and New Zealand College of 28. Ophthalmologists 29. Royal Dutch Shell 30. SAGE Publications 31. Springer 32. Taylor & Francis 33. Thieme 34. Thomson Healthcare 35. Thomson Scientific 36. U.S. Army Medical Department (AMEDD) 37. U.S. Army Research Institute 38. US Department of Defense 39. Westlaw 40. Wolters Kluwer Health
  • 120. The End of Part #1

Editor's Notes

  • #10: 5ft = 1.5m
  • #22: https://www.youtube.com/watch?v=wPSuO-zUHik
  • #24: Impact factor 3.4
  • #33: http://bmcmedinformdecismak.biomedcentral.com/articles/10.1186/1472-6947-12-67
  • #44: http://www.fda.gov/MedicalDevices/DigitalHealth/MobileMedicalApplications/ucm368743.htm
  • #47: Dr. Mohammed Habib
  • #48: http://www.fda.gov/downloads/MedicalDevices/DeviceRegulationandGuidance/GuidanceDocuments/UCM263366.pdf
  • #59: NHS:National Health Service NICE: National Institute for Health and Care Excellence (NICE)
  • #60: 750$$
  • #63: BNF=50 eu = 57$ Interaction= 30=34$
  • #99: http://www.dynamed.com/home/files/channel-assets/step-documents/levelsofevidencedynamedplus.pdf