This document discusses different ways that theories can be used in research studies. It describes three main approaches: 1) Minimal use where the theory provides a framework but is not integrated into the study; 2) Using concepts from theories to organize the research, usually for descriptive rather than testing purposes; 3) Explicitly testing models by deriving hypotheses from assumptions and testing them to support or refute the theory. It also provides examples of grounded theory studies, using existing theories as interpretive frameworks, and testing competing theories. Guidelines are presented for evaluating theory testing, development, and conceptual frameworks in nursing research.