The document discusses the challenges facing the UK economy in the 2010s after the 2008 recession, including high unemployment and a reliance on sectors like financial services that may not drive growth going forward. It argues the knowledge economy, including industries like creative/cultural, high tech, and low carbon energy, can help rebalance the economy and drive new jobs, especially in regions like the Thames Gateway. Developing skills, universities, science parks, and linkages between sectors will be important to support growth in these areas.