The document discusses the challenges faced by digital business leaders in today’s rapidly changing environment, emphasizing the importance of establishing an Enterprise Project Management Office (EPMO) to enhance organizational agility and strategic alignment. It highlights the necessity of strategic portfolio management (SPM) to effectively prioritize investments and respond to emerging digital demands, particularly with the advent of generative AI (GenAI) technologies. Recommendations for leveraging GenAI in strategic planning and execution are provided, advocating for proactive training and the integration of new technologies into existing SPM practices to optimize outcomes.